Dan Ye

Institutes of Biomedical Sciences, Fudan University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2025

Other Publications

Article	Year
DNAzyme-based faithful probing and pulldown to identify candidate biomarkers of low abundance. Nature chemistry\| PubMed ID: 37710046	2024
Pivotal study of iodine-131-labeled chimeric tumor necrosis treatment radioimmunotherapy in patients with advanced lung cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15735129	2005
Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1. Cell metabolism\| PubMed ID: 22225877	2012
The mechanisms of IDH mutations in tumorigenesis. Cell research\| PubMed ID: 22453240	2012
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes & development\| PubMed ID: 22677546	2012
IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23071358	2012
R-2-hydroxyglutarate as the key effector of IDH mutations promoting oncogenesis. Cancer cell\| PubMed ID: 23518346	2013
Pharmacokinetics and pharmacodynamics of recombinant human EPO-Fc fusion protein in vivo. PloS one\| PubMed ID: 23977338	2013
Tumor necrosis therapy antibody interleukin-2 fusion protein elicits prolonged and targeted antitumor effects in vivo. Applied microbiology and biotechnology\| PubMed ID: 24276620	2014
Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress. The EMBO journal\| PubMed ID: 24769394	2014
TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites. Cell research\| PubMed ID: 24971736	2014
WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation. Molecular cell\| PubMed ID: 25601757	2015
SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth. The EMBO journal\| PubMed ID: 25755250	2015
D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth. Oncotarget\| PubMed ID: 25825982	2015
Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS biology\| PubMed ID: 26356530	2015
Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. Cell reports\| PubMed ID: 26686626	2015
SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense. EMBO reports\| PubMed ID: 27113762	2016
Cancer: Suffocation of gene expression. Nature\| PubMed ID: 27533033	2016
Destabilization of Fatty Acid Synthase by Acetylation Inhibits De Novo Lipogenesis and Tumor Cell Growth. Cancer research\| PubMed ID: 27758890	2016
Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis. Hepatology (Baltimore, Md.)\| PubMed ID: 27774669	2017
Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. Molecular and cellular biology\| PubMed ID: 28137912	2017
SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice. Cell reports\| PubMed ID: 28614718	2017
Tissue-specific significance of BAP1 gene mutation in prognostic prediction and molecular taxonomy among different types of cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 28618948	2017
Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas. Scientific reports\| PubMed ID: 28765641	2017
HDAC10 promotes angiogenesis in endothelial cells through the PTPN22/ERK axis. Oncotarget\| PubMed ID: 28977867	2017
Long Noncoding RNA-1604 Orchestrates Neural Differentiation through the miR-200c/ZEB Axis. Stem cells (Dayton, Ohio)\| PubMed ID: 29205638	2018
Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates. Trends in cancer\| PubMed ID: 29458964	2018
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer. EMBO reports\| PubMed ID: 29491006	2018
Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis. Cell reports\| PubMed ID: 29562167	2018
SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response. Cell reports\| PubMed ID: 30404004	2018
Rapid diagnosis of IDH1-mutated gliomas by 2-HG detection with gas chromatography mass spectrometry. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 30573870	2019
SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress. PloS one\| PubMed ID: 30759120	2019
CRL3s: The BTB-CUL3-RING E3 Ubiquitin Ligases. Advances in experimental medicine and biology\| PubMed ID: 31898230	2020
The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming. Cell reports\| PubMed ID: 32668244	2020
Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein & cell\| PubMed ID: 32683582	2021
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B. Acta pharmacologica Sinica\| PubMed ID: 32796956	2021
Glis1 facilitates induction of pluripotency via an epigenome-metabolome-epigenome signalling cascade. Nature metabolism\| PubMed ID: 32839595	2020
Author Correction: Glis1 facilitates induction of pluripotency via an epigenome-metabolome-epigenome signalling cascade. Nature metabolism\| PubMed ID: 33033400	2020
A Study of Prognostic Factors of Chinese Patients with Gynecologic Tract Carcinosarcomas Prognosis of Gynecologic Carcinosarcomas. Cancer management and research\| PubMed ID: 33149683	2020
NAD Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion. Cell metabolism\| PubMed ID: 33171124	2021
Structural insights into TSC complex assembly and GAP activity on Rheb. Nature communications\| PubMed ID: 33436626	2021
The diagnostic value of lower glucose consumption for IDH1 mutated gliomas on FDG-PET. BMC cancer\| PubMed ID: 33472598	2021
The Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas. Frontiers in cell and developmental biology\| PubMed ID: 34079802	2021
Secondary infection in severe and critical COVID-19 patients in China: a multicenter retrospective study. Annals of palliative medicine\| PubMed ID: 34379989	2021
Berberine Improves the Symptoms of DHEA-Induced PCOS Rats by Regulating Gut Microbiotas and Metabolites. Gynecologic and obstetric investigation\| PubMed ID: 34515131	2021
Cancer metabolism and tumor microenvironment: fostering each other? Science China. Life sciences\| PubMed ID: 34846643	2022
Driver mutations of intrahepatic cholangiocarcinoma shape clinically relevant genomic clusters with distinct molecular features and therapeutic vulnerabilities. Theranostics\| PubMed ID: 34987644	2022
Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity. Science advances\| PubMed ID: 35080973	2022
Ten-eleven translocation-2 inactivation restrains IL-10-producing regulatory B cells to enable antitumor immunity in hepatocellular carcinoma. Hepatology (Baltimore, Md.)\| PubMed ID: 35243663	2023
Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses. Nature cell biology\| PubMed ID: 35256775	2022
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis. Journal of hepatology\| PubMed ID: 35292350	2022
WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy. Molecular cell\| PubMed ID: 35429439	2022
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics. Nature metabolism\| PubMed ID: 35606596	2022
Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation. Cell death and differentiation\| PubMed ID: 35614132	2022
A retrospective analysis of relapse-related factors for ovarian borderline tumors. American journal of translational research\| PubMed ID: 36105008	2022
LncCMRR Plays an Important Role in Cardiac Differentiation by Regulating the Purb/Flk1 Axis. Stem cells (Dayton, Ohio)\| PubMed ID: 36318802	2023
CD36 cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor. Cell discovery\| PubMed ID: 36878933	2023
The immunometabolite itaconate stimulates OXGR1 to promote mucociliary clearance during the pulmonary innate immune response. The Journal of clinical investigation\| PubMed ID: 36919698	2023
Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy. Science advances\| PubMed ID: 37115931	2023
R-loop-dependent promoter-proximal termination ensures genome stability. Nature\| PubMed ID: 37557913	2023
Glucose-induced and ChREBP: MLX-mediated lipogenic program promotes hepatocellular carcinoma development. Oncogene\| PubMed ID: 37684408	2023
Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors. Nature communications\| PubMed ID: 37723178	2023
Prolonged second stage of labor is associated with persistent urinary retention after forceps delivery: An observational study. Medicine\| PubMed ID: 37746990	2023
Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness. Cell reports\| PubMed ID: 37831605	2023
Using NMR to Monitor TET-Dependent Methylcytosine Dioxygenase Activity and Regulation. ACS chemical biology\| PubMed ID: 38193366	2024
Itaconate in host inflammation and defense. Trends in endocrinology and metabolism: TEM\| PubMed ID: 38448252	2024
Reactivating PTEN to impair glioma stem cells by inhibiting cytosolic iron-sulfur assembly. Science translational medicine\| PubMed ID: 38507470	2024
Dynamic changes in RNA mA and 5 hmC influence gene expression programs during macrophage differentiation and polarisation. Cellular and molecular life sciences : CMLS\| PubMed ID: 38780787	2024
TET2-STAT3-CXCL5 nexus promotes neutrophil lipid transfer to fuel lung adeno-to-squamous transition. The Journal of experimental medicine\| PubMed ID: 38805014	2024
Rapid detection of IDH mutations in gliomas by intraoperative mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 38805277	2024
Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity. Cell reports\| PubMed ID: 38829739	2024
PCK2 maintains intestinal homeostasis and prevents colitis by protecting antibody-secreting cells from oxidative stress. Immunology\| PubMed ID: 38934051	2024
Itaconate and dimethyl itaconate upregulate IL-6 production in the LPS-induced inflammation in mice. Journal of leukocyte biology\| PubMed ID: 38941443	2024
Genetically predicted metabolites mediate the association between immune cells and metabolic dysfunction-associated steatotic liver disease: a mendelian randomization study. Lipids in health and disease\| PubMed ID: 39148061	2024
Temsirolimus inhibits FSP1 enzyme activity to induce ferroptosis and restrain liver cancer progression. Journal of molecular cell biology\| PubMed ID: 39313331	2025
A cofactor-induced repressive type of transcription factor condensation can be induced by synthetic peptides to suppress tumorigenesis. The EMBO journal\| PubMed ID: 39358623	2024
Metabolite regulation of epigenetics in cancer. Cell reports\| PubMed ID: 39368084	2024
Gene therapy for diffuse pleural mesotheliomas in preclinical models by concurrent expression of NF2 and SuperHippo. Cell reports. Medicine\| PubMed ID: 39368484	2024
Angiomotin cleavage promotes leader formation and collective cell migration. Developmental cell\| PubMed ID: 39389053	2025
Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade. Cancer cell\| PubMed ID: 39423817	2024
Incidence and Risk Factors of Ophthalmic Nerve Palsy in Patients With Tuberculous Meningitis: A Retrospective Study and Literature Review. Open forum infectious diseases\| PubMed ID: 39665113	2024
Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation. Cell reports\| PubMed ID: 39792560	2025
Correcting mitochondrial loss mitigates NOTCH1-related aortopathy in mice. Nature cardiovascular research\| PubMed ID: 39809927	2025
Risk Factors for Disseminated Tuberculosis and Associated Survival in Adults Without Human Immunodeficiency Virus. Open forum infectious diseases\| PubMed ID: 39817036	2025
Author Correction: R-loop-dependent promoter-proximal termination ensures genome stability. Nature\| PubMed ID: 39833484	2025
WWC proteins-mediated compensatory mechanism restricts schwannomatosis driven by loss of function. Science advances\| PubMed ID: 39841844	2025
Mitochondrial NAD deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm. Nature cardiovascular research\| PubMed ID: 39843801	2025
Targeting IRG1 in tumor-associated macrophages for cancer therapy. Protein & cell\| PubMed ID: 39965122	2025
Pathogen-derived glyoxylate inhibits Tet2 DNA dioxygenase to facilitate bacterial persister formation. Cell metabolism\| PubMed ID: 40037360	2025
Clinical efficacy of linezolid in the treatment of tuberculous meningitis: a retrospective analysis and literature review. BMC infectious diseases\| PubMed ID: 40188033	2025
NPR is an independent risk factor for predicting all-cause mortality in patients with metabolic dysfunction-associated steatotic liver disease: evidence from NHANES 2007-2020. Population health metrics\| PubMed ID: 40281626	2025
Prevalence of MAFLD in the U.S. based on NHANES 2009-2018: differences in demographic characteristics, physical indices and lifestyle conditions. BMC gastroenterology\| PubMed ID: 40316899	2025
Clinical characteristics and outcomes of tuberculosis and non-tuberculous mycobacteria infections: a population-based study of concurrent and sequential infections. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology\| PubMed ID: 40343627	2025
Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis. Bone research\| PubMed ID: 40500265	2025
Metabolism archetype cancer cells induce protumor TREM2 macrophages via oxLDL-mediated metabolic interplay in hepatocellular carcinoma. Nature communications\| PubMed ID: 40695827	2025