Alison P. McGuigan

Institute of Biomedical Engineering, University of Toronto

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Collagen/poloxamine hydrogels: cytocompatibility of embedded HepG2 cells and surface-attached endothelial cells. Tissue engineering\| PubMed ID: 16411826	2005
Vascularized organoid engineered by modular assembly enables blood perfusion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16864785	2006
Tissue factor and thrombomodulin expression on endothelial cell-seeded collagen modules for tissue engineering. Journal of biomedical materials research. Part A\| PubMed ID: 17111414	2007
The influence of biomaterials on endothelial cell thrombogenicity. Biomaterials\| PubMed ID: 17316788	2007
Fabrication of cell-containing gel modules to assemble modular tissue-engineered constructs [corrected]. Nature protocols\| PubMed ID: 17406556	2006
Design criteria for a modular tissue-engineered construct. Tissue engineering\| PubMed ID: 17439395	2007
Design and fabrication of sub-mm-sized modules containing encapsulated cells for modular tissue engineering. Tissue engineering\| PubMed ID: 17582838	2007
Modular tissue engineering: fabrication of a gelatin-based construct. Journal of tissue engineering and regenerative medicine\| PubMed ID: 18038402	2007
The thrombogenicity of human umbilical vein endothelial cell seeded collagen modules. Biomaterials\| PubMed ID: 18325586	2008
A fast and accessible methodology for micro-patterning cells on standard culture substrates using Parafilm™ inserts. PloS one\| PubMed ID: 21687691	2011
Tools for micropatterning epithelial cells into microcolonies on transwell filter substrates. Lab on a chip\| PubMed ID: 21860858	2011
Design principles for generating robust gene expression patterns in dynamic engineered tissues. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 23369944	2013
An algorithm to quantify correlated collective cell migration behavior. BioTechniques\| PubMed ID: 23384179	2013
Challenges and opportunities for tissue-engineering polarized epithelium. Tissue engineering. Part B, Reviews\| PubMed ID: 23789630	2014
A simple and rapid method for generating patterned co-cultures with stable interfaces. BioTechniques\| PubMed ID: 23834381	2013
Nonautonomous contact guidance signaling during collective cell migration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24449852	2014
Micropatterning cells on permeable membrane filters. Methods in cell biology\| PubMed ID: 24560510	2014
Multiwell plate tools for controlling cellular alignment with grooved topography. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24687428	2014
A microgroove patterned multiwell cell culture plate for high-throughput studies of cell alignment. Biotechnology and bioengineering\| PubMed ID: 24889796	2014
A microfluidic device to apply shear stresses to polarizing ciliated airway epithelium using air flow. Biomicrofluidics\| PubMed ID: 25553181	2014
Micropatterning strategies to engineer controlled cell and tissue architecture in vitro. BioTechniques\| PubMed ID: 25605576	2015
An in vitro model of tissue boundary formation for dissecting the contribution of different boundary forming mechanisms. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 25609037	2015
Topographically grooved gel inserts for aligning epithelial cells during air-liquid-interface culture. Biomaterials science\| PubMed ID: 26214196	2015
A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients. Nature materials\| PubMed ID: 26595121	2016
Tissue Patterning: Translating Design Principles from In Vivo to In Vitro. Annual review of biomedical engineering\| PubMed ID: 26789696	2016
Patterning cellular compartments within TRACER cultures using sacrificial gelatin printing. Biofabrication\| PubMed ID: 27631341	2016
Diabetic wound regeneration using peptide-modified hydrogels to target re-epithelialization. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27647919	2016
Development of TRACER: tissue roll for analysis of cellular environment and response. Biofabrication\| PubMed ID: 27754980	2016
Modulation of cellular polarization and migration by ephrin/Eph signal-mediated boundary formation. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 29120470	2017
Design of biomimetic substrates for long-term maintenance of alveolar epithelial cells. Biomaterials science\| PubMed ID: 29327014	2018
The Current Landscape of 3D In Vitro Tumor Models: What Cancer Hallmarks Are Accessible for Drug Discovery? Advanced healthcare materials\| PubMed ID: 29350495	2018
A TRACER 3D Co-Culture tumour model for head and neck cancer. Biomaterials\| PubMed ID: 29490260	2018
A three-dimensional engineered heterogeneous tumor model for assessing cellular environment and response. Nature protocols\| PubMed ID: 30190554	2018
Local cell coordination does not alter individual cell migration during collective migration but does impact cellular exchange events. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 31147696	2019
Development of a bioprinting approach for automated manufacturing of multi-cell type biocomposite TRACER strips using contact capillary-wicking. Biofabrication\| PubMed ID: 31553953	2019
Gels for Live Analysis of Compartmentalized Environments (GLAnCE): A tissue model to probe tumour phenotypes at tumour-stroma interfaces. Biomaterials\| PubMed ID: 31683122	2020
The life cycle of cancer-associated fibroblasts within the tumour stroma and its importance in disease outcome. British journal of cancer\| PubMed ID: 31992854	2020
A TRACER culture invasion assay to probe the impact of cancer associated fibroblasts on head and neck squamous cell carcinoma cell invasiveness. Biomaterials science\| PubMed ID: 32347842	2020
Assembly of lung progenitors into developmentally-inspired geometry drives differentiation via cellular tension. Biomaterials\| PubMed ID: 32474250	2020
Current strategies and opportunities to manufacture cells for modeling human lungs. Advanced drug delivery reviews\| PubMed ID: 32835746	2020
Matrix Stiffness-Regulated Growth of Breast Tumor Spheroids and Their Response to Chemotherapy. Biomacromolecules\| PubMed ID: 33136364	2021
Applications of Omics Technologies for Three-Dimensional Disease Models. Tissue engineering. Part C, Methods\| PubMed ID: 33406987	2021
Easy and robust micropatterning using fibrinogen anchors. The Journal of cell biology\| PubMed ID: 33427874	2021
Microfluidic Arrays of Breast Tumor Spheroids for Drug Screening and Personalized Cancer Therapies. Advanced healthcare materials\| PubMed ID: 34636180	2022
Planar organization of airway epithelial cell morphology using hydrogel grooves during ciliogenesis fails to induce ciliary alignment. Biomaterials science\| PubMed ID: 34897300	2022
Guided Self-Assembly of ES-Derived Lung Progenitors into Biomimetic Tube Structures That Impact Cell Differentiation. Bioengineering (Basel, Switzerland)\| PubMed ID: 34940362	2021
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity. Immunity\| PubMed ID: 35139353	2022
3D microgels to quantify tumor cell properties and therapy response dynamics. Biomaterials\| PubMed ID: 35231786	2022
Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids. Nature communications\| PubMed ID: 35304464	2022
REVOLVER: A low-cost automated protein purifier based on parallel preparative gravity column workflows. HardwareX\| PubMed ID: 35509899	2022
A three-dimensional human adipocyte model of fatty acid-induced obesity. Biofabrication\| PubMed ID: 35896099	2022
An Engineered Paper-Based 3D Coculture Model of Pancreatic Cancer to Study the Impact of Tissue Architecture and Microenvironmental Gradients on Cell Phenotype. Advanced healthcare materials\| PubMed ID: 36308030	2023
An off-the-shelf multi-well scaffold-supported platform for tumour organoid-based tissues. Biomaterials\| PubMed ID: 36343611	2022
An Automation Workflow for High-Throughput Manufacturing and Analysis of Scaffold-Supported 3D Tissue Arrays. Advanced healthcare materials\| PubMed ID: 37086259	2023
Exploring New Dimensions of Tumor Heterogeneity: The Application of Single Cell Analysis to Organoid-Based 3D In Vitro Models. Advanced healthcare materials\| PubMed ID: 37589373	2023
Characterization of an -Allylglyoxylamide-Based Bioorthogonal Nitrone Trap. Bioconjugate chemistry\| PubMed ID: 38051144	2023
Design Parameters for a Mass Cytometry Detectable HaloTag Ligand. Bioconjugate chemistry\| PubMed ID: 38112314	2024
Mini-MEndR: a miniaturized 96-well predictive assay to evaluate muscle stem cell-mediated repair. BMC methods\| PubMed ID: 38872952	2024
Applications and evolution of 3D cancer-immune cell models. Trends in biotechnology\| PubMed ID: 39025680	2024
Lateral Assessment of Mucomimetic Hydrogels to Evaluate Correlation between Microscopic and Macroscopic Properties. Macromolecular bioscience\| PubMed ID: 39374341	2024
The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state. Biomaterials\| PubMed ID: 39395244	2025
Analysis of an engineered organoid model of pancreatic cancer identifies hypoxia as a contributing factor in determining transcriptional subtypes. Scientific reports\| PubMed ID: 40604231	2025