Darren Svirskis

School of Pharmacy, University of Auckland

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Electrochemically controlled drug delivery based on intrinsically conducting polymers. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 20359512	2010
A stability indicating HPLC method for the determination of electrochemically controlled release of risperidone. Journal of chromatographic science\| PubMed ID: 22080806	2011
In-situ phase transition from microemulsion to liquid crystal with the potential of prolonged parenteral drug delivery. International journal of pharmaceutics\| PubMed ID: 22548845	2012
High surface area polypyrrole scaffolds for tunable drug delivery. International journal of pharmaceutics\| PubMed ID: 23318368	2013
The use of ethanol in paediatric formulations in New Zealand. European journal of pediatrics\| PubMed ID: 23440480	2013
Electrically switchable polypyrrole film for the tunable release of progesterone. Therapeutic delivery\| PubMed ID: 23442078	2013
Development of mucoadhesive floating hollow beads of acyclovir with gastroretentive properties. Pharmaceutical development and technology\| PubMed ID: 23859639	2014
Chemical stability of extemporaneously compounded omeprazole formulations: a comparison of two methods of compounding. International journal of pharmaceutical compounding\| PubMed ID: 23966480	2009
A study of microemulsions as prolonged-release injectables through in-situ phase transition. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24316265	2014
Physicochemical characterization of asulacrine towards the development of an anticancer liposomal formulation via active drug loading: stability, solubility, lipophilicity and ionization. International journal of pharmaceutics\| PubMed ID: 25079434	2014
An investigation into the stability and sterility of citric acid solutions used for cough reflex testing. Dysphagia\| PubMed ID: 25150508	2014
Implants for drug delivery to the posterior segment of the eye: a focus on stimuli-responsive and tunable release systems. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 25307997	2014
Physicochemical characterization of native glycyl-l-histidyl-l-lysine tripeptide for wound healing and anti-aging: a preformulation study for dermal delivery. Pharmaceutical development and technology\| PubMed ID: 25384620	2016
Development and validation of a stability indicating isocratic HPLC method for gemcitabine with application to drug release from poly lactic-co-glycolic acid nanoparticles and enzymatic degr... The Journal of pharmacy and pharmacology\| PubMed ID: 26369422	2015
Supercritical Fluid Technologies to Fabricate Proliposomes. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques\| PubMed ID: 26670368	2015
Injectable thermosensitive gelling delivery system for the sustained release of lidocaine. Therapeutic delivery\| PubMed ID: 27250538	2016
Controlled release drug delivery systems to improve post-operative pharmacotherapy. Drug delivery and translational research\| PubMed ID: 27329201	2016
Conducting Polymers as Electrode Coatings for Neuronal Multi-electrode Arrays. Trends in biotechnology\| PubMed ID: 27422455	2017
Conducting polymers with defined micro- or nanostructures for drug delivery. Biomaterials\| PubMed ID: 27728814	2016
Magnetic Resonance Imaging to Visualize Disintegration of Oral Formulations. Journal of pharmaceutical sciences\| PubMed ID: 27964901	2017
Design of microemulsion system suitable for the oral delivery of poorly aqueous soluble beta-carotene. Pharmaceutical development and technology\| PubMed ID: 28125945	2018
Cyclic-RGDyC functionalized liposomes for dual-targeting of tumor vasculature and cancer cells in glioblastoma: An in vitro boron neutron capture therapy study. Oncotarget\| PubMed ID: 28402271	2017
Development, Validation and Application of a Stability Indicating HPLC Method to Quantify Lidocaine from Polyethylene-co-Vinyl Acetate (EVA) Matrices and Biological Fluids. Journal of chromatographic science\| PubMed ID: 28498908	2017
Taking the lead from our colleagues in medical education: the use of images of the in-vivo setting in teaching concepts of pharmaceutical science. Journal of pharmaceutical policy and practice\| PubMed ID: 28725441	2017
In vitro and ex vivo characterisation of an in situ gelling formulation for sustained lidocaine release with potential use following knee arthroplasty. Drug delivery and translational research\| PubMed ID: 29411295	2018
Free standing PEDOT films prepared by vapour phase polymerisation as electrically tuneable barriers to drug permeability. Materials science & engineering. C, Materials for biological applications\| PubMed ID: 29519436	2018
Stability of vincristine sulfate, doxorubicin hydrochloride and etoposide phosphate admixtures in polyisoprene elastomeric pump supporting transition of the EPOCH regimen to outpatient care. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners\| PubMed ID: 29540104	2019
N-trimethyl chitosan nanoparticles and CSKSSDYQC peptide: N-trimethyl chitosan conjugates enhance the oral bioavailability of gemcitabine to treat breast cancer. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 29548985	2018
Micelle directed chemical polymerization of polypyrrole particles for the electrically triggered release of dexamethasone base and dexamethasone phosphate. International journal of pharmaceutics\| PubMed ID: 29581065	2018
Comparing human peritoneal fluid and phosphate-buffered saline for drug delivery: do we need bio-relevant media? Drug delivery and translational research\| PubMed ID: 29582351	2018
Intravenous Local Anaesthetic Compared with Intraperitoneal Local Anaesthetic in Abdominal Surgery: A Systematic Review. World journal of surgery\| PubMed ID: 29666908	2018
Analysis of the Postoperative Periarticular Environment and Influence on Sustained Drug Delivery From a Gel Formulation. Journal of pharmaceutical sciences\| PubMed ID: 29777717	2018
The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded Levothyroxine Suspensions. International journal of pharmaceutical compounding\| PubMed ID: 29877863	2018
A Stability Indicating HPLC Method to Determine Actual Content and Stability of Nicotine within Electronic Cigarette Liquids. International journal of environmental research and public health\| PubMed ID: 30104538	2018
Using Technology in Pharmacy Education: Pharmacy Student Performance and Perspectives When Visual Aids Are Integrated Into Learning. Frontiers in pharmacology\| PubMed ID: 30319411	2018
Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function. Zebrafish\| PubMed ID: 30724716	2019
Protocol for the Gut Bugs Trial: a randomised double-blind placebo-controlled trial of gut microbiome transfer for the treatment of obesity in adolescents. BMJ open\| PubMed ID: 31005929	2019
Can intracellular drug delivery using hyaluronic acid functionalised pH-sensitive liposomes overcome gemcitabine resistance in pancreatic cancer? Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 31096017	2019
Subcutaneous nicotine delivery via needle-free jet injection: A porcine model. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 31150748	2019
Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation. Advanced healthcare materials\| PubMed ID: 31168967	2019
Optimisation of glutathione conjugation to liposomes quantified with a validated HPLC assay. International journal of pharmaceutics\| PubMed ID: 31229530	2019
Make it simple: long-term stable gradient generation in a microfluidic microdevice. Biomedical microdevices\| PubMed ID: 31346791	2019
A Macroscopic Diffusion-Based Gradient Generator to Establish Concentration Gradients of Soluble Molecules Within Hydrogel Scaffolds for Cell Culture. Frontiers in chemistry\| PubMed ID: 31620430	2019
Determining Neurotrophin Gradients in Vitro To Direct Axonal Outgrowth Following Spinal Cord Injury. ACS chemical neuroscience\| PubMed ID: 31825204	2020
Formulation strategies to modulate drug release from poloxamer based in situ gelling systems. Expert opinion on drug delivery\| PubMed ID: 32067500	2020
Association between perioperative intraperitoneal local anaesthetic infusion and long-term survival and cancer recurrence after colectomy: follow-up analysis of a previous randomized control... ANZ journal of surgery\| PubMed ID: 32090464	2020
A NAG-Guided Nano-Delivery System for Redox- and pH-Triggered Intracellularly Sequential Drug Release in Cancer Cells. International journal of nanomedicine\| PubMed ID: 32103941	2020
The Effect of Manufacturer on the Compounding of Omeprazole Suspensions and Their Stability Assessment. International journal of pharmaceutical compounding\| PubMed ID: 32196476	2020
Non-invasive neuromodulation for bowel, bladder and sexual restoration following spinal cord injury: A systematic review. Clinical neurology and neurosurgery\| PubMed ID: 32334284	2020
Alcohol-free Extemporaneous Formulations of Furosemide Are Chemically and Physically Stable in Ora-Blend Products for 30 Days. International journal of pharmaceutical compounding\| PubMed ID: 32401745	2020
Ex vivo evaluation of the influence of pH on the ophthalmic safety, antibacterial efficacy and storage stability of povidone-iodine. Clinical & experimental optometry\| PubMed ID: 32495387
Stretchable Electronics Based on Laser Structured, Vapor Phase Polymerized PEDOT/Tosylate. Polymers\| PubMed ID: 32722387	2020
A simultaneous optical and electrical in-vitro neuronal recording system to evaluate microelectrode performance. PloS one\| PubMed ID: 32817653	2020
Conducting polymer hydrogels for electrically responsive drug delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 32877745	2020
A non-opioid analgesic implant for sustained post-operative intraperitoneal delivery of lidocaine, characterized using an ovine model. Biomaterials\| PubMed ID: 32977258	2020
High prevalence of undiagnosed comorbidities among adolescents with obesity. Scientific reports\| PubMed ID: 33208826	2020
Effects of Fecal Microbiome Transfer in Adolescents With Obesity: The Gut Bugs Randomized Controlled Trial. JAMA network open\| PubMed ID: 33346848	2020
Externally triggered release of growth factors - A tissue regeneration approach. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 33600882	2021
Intravenous Local Anesthetic Compared With Intraperitoneal Local Anesthetic in Laparoscopic Colectomy: A Double-blind Randomized Controlled Trial. Annals of surgery\| PubMed ID: 33630453	2022
Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery. International journal of pharmaceutics\| PubMed ID: 33933647	2021
Strain engraftment competition and functional augmentation in a multi-donor fecal microbiota transplantation trial for obesity. Microbiome\| PubMed ID: 33985595	2021
Transcutaneous Electrical Stimulation for Neurogenic Bladder Dysfunction Following Spinal Cord Injury: Meta-Analysis of Randomized Controlled Trials. Neuromodulation : journal of the International Neuromodulation Society\| PubMed ID: 34013608	2021
Injectable thermoresponsive gels offer sustained dual release of bupivacaine hydrochloride and ketorolac tromethamine for up to two weeks. International journal of pharmaceutics\| PubMed ID: 34051318	2021
Stretchable microchannel-on-a-chip: A simple model for evaluating the effects of uniaxial strain on neuronal injury. Journal of neuroscience methods\| PubMed ID: 34343573	2021
Photosensitive drug delivery systems for cancer therapy: Mechanisms and applications. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 34481021	2021
N-trimethyl chitosan coated nano-complexes enhance the oral bioavailability and chemotherapeutic effects of gemcitabine. Carbohydrate polymers\| PubMed ID: 34560993	2021
An interpenetrating and patternable conducting polymer hydrogel for electrically stimulated release of glutamate. Acta biomaterialia\| PubMed ID: 34644612	2022
Stability and compatibility of admixtures containing bupivacaine hydrochloride and ketorolac tromethamine for parenteral use. European journal of hospital pharmacy : science and practice\| PubMed ID: 34663584	2023
Topical Versus Oral Metronidazole After Excisional Hemorrhoidectomy: A Double-Blind Randomized Controlled Trial. Diseases of the colon and rectum\| PubMed ID: 34897211	2022
Optimised techniques for high-throughput screening of differentiated SH-SY5Y cells and application for neurite outgrowth assays. Scientific reports\| PubMed ID: 34907283	2021
Sustained Delivery of Lactoferrin Using Poloxamer Gels for Local Bone Regeneration in a Rat Calvarial Defect Model. Materials (Basel, Switzerland)\| PubMed ID: 35009359	2021
Detection of Anastomotic Leakage Following Elective Colonic Surgery: Results of the Prospective Biomarkers and Anastomotic Leakage (BALL) Study. The Journal of surgical research\| PubMed ID: 35033821	2022
The involvement of extracellular vesicles in the transcytosis of nanoliposomes through brain endothelial cells, and the impact of liposomal pH-sensitivity. Materials today. Bio\| PubMed ID: 35198960	2022
Injectable In Situ Gelling System for Sustained Nicotine Delivery as a Replacement Therapy for Smoking Cessation. Gels (Basel, Switzerland)\| PubMed ID: 35200495	2022
Preformulation studies of thymopentin: analytical method development, physicochemical properties, kinetic degradation investigations and formulation perspective. Drug development and industrial pharmacy\| PubMed ID: 35234086	2021
In situ gelling system for sustained intraarticular delivery of bupivacaine and ketorolac in sheep. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 35364255	2022
Non-transferrin bound iron. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 35398023	2022
Evaluation of the inflammatory profile following uncomplicated elective colectomy. ANZ journal of surgery\| PubMed ID: 35482412	2022
A Subdural Bioelectronic Implant to Record Electrical Activity from the Spinal Cord in Freely Moving Rats. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 35499184	2022
Dual or multiple drug loaded nanoparticles to target breast cancer stem cells. RSC advances\| PubMed ID: 35518295	2020
Conducting polymer hydrogels with electrically-tuneable mechanical properties as dynamic cell culture substrates. Biomaterials advances\| PubMed ID: 35527144	2022
Exploiting hydrogen bonding to enhance lidocaine loading and stability in a poly ethylene-co-vinyl acetate carrier matrix. International journal of pharmaceutics\| PubMed ID: 35569627	2022
Quantification and composition of pharmaceutical waste in New Zealand. Journal of material cycles and waste management\| PubMed ID: 35570848	2022
Development of agarose-gelatin bioinks for extrusion-based bioprinting and cell encapsulation. Biomedical materials (Bristol, England)\| PubMed ID: 35654031	2022
Patternable Gelatin Methacrylate/PEDOT/Polystyrene Sulfonate Microelectrode Coatings for Neuronal Recording. ACS biomaterials science & engineering\| PubMed ID: 35976694	2022
Exploring ex vivo peptideolysis of thymopentin and lipid-based nanocarriers towards oral formulations. International journal of pharmaceutics\| PubMed ID: 35995317	2022
Increasing the Hydrophobic Component of Poloxamers and the Inclusion of Salt Extend the Release of Bupivacaine from Injectable In Situ Gels, While Common Polymer Additives Have Little Effect... Gels (Basel, Switzerland)\| PubMed ID: 36005085	2022
The role of glutathione conjugation on the transcellular transport process of PEGylated liposomes across the blood brain barrier. International journal of pharmaceutics\| PubMed ID: 36055442	2022
Can Targeting Sphincter Spasm Reduce Post-Haemorrhoidectomy Pain? A Systematic Review and Meta-Analysis. World journal of surgery\| PubMed ID: 36357803	2023
Investigating the influence of ultrasound parameters on ibuprofen drug release from hydrogels. Drug delivery and translational research\| PubMed ID: 36509966	2023
Safety and efficacy of intraosseous ropivacaine in lower extremity (SORE) study. ANZ journal of surgery\| PubMed ID: 36627759	2023
Electrically responsive release of proteins from conducting polymer hydrogels. Acta biomaterialia\| PubMed ID: 36640949	2023
A simple and reliable isocratic high-performance chromatographic assay for the simultaneous determination of hydrophilic benzophenone-4 and lipophilic octocrylene in sunscreens. International journal of cosmetic science\| PubMed ID: 37038989	2023
Spinal intradural electrodes: opportunities, challenges and translation to the clinic. Neural regeneration research\| PubMed ID: 37721274	2024
Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review. APL bioengineering\| PubMed ID: 37736015	2023
Hydroxypropyl Methylcellulose Bioadhesive Hydrogels for Topical Application and Sustained Drug Release: The Effect of Polyvinylpyrrolidone on the Physicomechanical Properties of Hydrogel. Pharmaceutics\| PubMed ID: 37765328	2023
An open-label pilot trial assessing tolerability and feasibility of LSD microdosing in patients with major depressive disorder (LSDDEP1). Pilot and feasibility studies\| PubMed ID: 37798662	2023
Roadmap on multifunctional materials for drug delivery. JPhys materials\| PubMed ID: 38144214	2024
Translating ultrasound-mediated drug delivery technologies for CNS applications. Advanced drug delivery reviews\| PubMed ID: 38452815	2024
Encapsulation of the growth factor neurotrophin-3 in heparinised poloxamer hydrogel stabilises bioactivity and provides sustained release. Biomaterials advances\| PubMed ID: 38522310	2024
Cellular Uptake and Transport Mechanism Investigations of PEGylated Niosomes for Improving the Oral Delivery of Thymopentin. Pharmaceutics\| PubMed ID: 38543291	2024
Synthesis and characterization of antimicrobial colloidal polyanilines. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 38608465	2024
Cryo-Milled β-Glucan Nanoparticles for Oral Drug Delivery. Pharmaceutics\| PubMed ID: 38675207	2024
A Randomized Controlled Trial of Topical Analgesia Posthemorrhoidectomy (TAPH Trial). Diseases of the colon and rectum\| PubMed ID: 38871679	2024
LSDDEP2: study protocol for a randomised, double-dummy, triple-blind, active placebo-controlled, parallel groups trial of LSD microdosing in patients with major depressive disorder. Trials\| PubMed ID: 39182140	2024
Safe subdural administration and retention of a neurotrophin-3-delivering hydrogel in a rat model of spinal cord injury. Scientific reports\| PubMed ID: 39455822	2024
Actuated Hydrogel Platforms To Study Brain Cell Behavior. Advanced healthcare materials\| PubMed ID: 40091290	2025
Advancements in Mercury-Free Electrochemical Sensors for Iron Detection: A Decade of Progress in Electrode Materials and Modifications. Sensors (Basel, Switzerland)\| PubMed ID: 40096308	2025
Pharmacokinetics of Intraperitoneal Lidocaine for Sustained Postoperative Analgesia in Adults. European journal of drug metabolism and pharmacokinetics\| PubMed ID: 40342039	2025
Daily electric field treatment improves functional outcomes after thoracic contusion spinal cord injury in rats. Nature communications\| PubMed ID: 40571679	2025