Lijian Hui

State Key Laboratory of Cell Biology, University of Chinese Academy of Sciences

Affiliated withUniversity of Chinese Academy of Sciences

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Hepatic loss of survivin impairs postnatal liver development and promotes expansion of hepatic progenitor cells in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 23813590	2013
Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function. Cell reports\| PubMed ID: 24685134	2014
Hepatic p38α regulates gluconeogenesis by suppressing AMPK. Journal of hepatology\| PubMed ID: 25595884	2015
Hepatocellular carcinoma repression by TNFα-mediated synergistic lethal effect of mitosis defect-induced senescence and cell death sensitization. Hepatology (Baltimore, Md.)\| PubMed ID: 27177758	2016
Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers. Scientific reports\| PubMed ID: 27273737	2016
Hepatic Loss of Borealin Impairs Postnatal Liver Development, Regeneration, and Hepatocarcinogenesis. The Journal of biological chemistry\| PubMed ID: 27542413	2016
Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model. Scientific reports\| PubMed ID: 27934920	2016
High-throughput screening for Survivin and Borealin interaction inhibitors in hepatocellular carcinoma. Biochemical and biophysical research communications\| PubMed ID: 28153734	2017
Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress. Cell research\| PubMed ID: 28322253	2017
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK. PLoS pathogens\| PubMed ID: 28753655	2017
Chemical Cocktails Enable Hepatic Reprogramming of Mouse Fibroblasts with a Single Transcription Factor. Stem cell reports\| PubMed ID: 28757167	2017
Arid1a regulates response to anti-angiogenic therapy in advanced hepatocellular carcinoma. Journal of hepatology\| PubMed ID: 29113912	2018
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer. Cancer cell\| PubMed ID: 29136504	2017
Distinct Gene Expression and Epigenetic Signatures in Hepatocyte-like Cells Produced by Different Strategies from the Same Donor. Stem cell reports\| PubMed ID: 29173899	2017
Cas9-nickase-mediated genome editing corrects hereditary tyrosinemia in rats. The Journal of biological chemistry\| PubMed ID: 29507093	2018
Metabolic benefits of inhibition of p38α in white adipose tissue in obesity. PLoS biology\| PubMed ID: 29750781	2018
Chronic Liver Injury Induces Conversion of Biliary Epithelial Cells into Hepatocytes. Cell stem cell\| PubMed ID: 29937200	2018
Paper supported long-term 3D liver co-culture model for the assessment of hepatotoxic drugs. Toxicology research\| PubMed ID: 30090558	2018
Endothelial cell fitness dictates the source of regenerating liver vasculature. The Journal of experimental medicine\| PubMed ID: 30194265	2018
In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity. Cell stem cell\| PubMed ID: 30416071	2018
Conversion of Fibroblasts to Hepatocytes In Vitro. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 30536093	2019
Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals. Molecular metabolism\| PubMed ID: 30579932	2019
Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation. Cell reports\| PubMed ID: 30970249	2019
YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis. Cell reports\| PubMed ID: 31018132	2019
A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling. Cell stem cell\| PubMed ID: 31271748	2019
Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes. Nature cell biology\| PubMed ID: 31332348	2019
ECM1 Prevents Activation of Transforming Growth Factor β, Hepatic Stellate Cells, and Fibrogenesis in Mice. Gastroenterology\| PubMed ID: 31362006	2019
A Pharmacogenomic Landscape in Human Liver Cancers. Cancer cell\| PubMed ID: 31378681	2019
Cell Plasticity in Liver Regeneration. Trends in cell biology\| PubMed ID: 32200807	2020
Progress in human liver organoids. Journal of molecular cell biology\| PubMed ID: 32236564	2020
A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis. Cell reports\| PubMed ID: 33086070	2020
Integrative analysis reveals novel driver genes and molecular subclasses of hepatocellular carcinoma. Aging\| PubMed ID: 33221766	2020
Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells. Cell reports\| PubMed ID: 33296648	2020
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah Rag2 IL2rg Rats. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 34382351	2021
Recent advances in tissue stem cells. Science China. Life sciences\| PubMed ID: 34865207	2021
Cell identity conversion in liver regeneration after injury. Current opinion in genetics & development\| PubMed ID: 35644120	2022
Pre-existing chromatin accessibility of switchable repressive compartment delineates cell plasticity. National science review\| PubMed ID: 35795460	2022
Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 36266974	2022
Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation. Signal transduction and targeted therapy\| PubMed ID: 36627278	2023
Human endoderm stem cells reverse inflammation-related acute liver failure through cystatin SN-mediated inhibition of interferon signaling. Cell research\| PubMed ID: 36670290	2023
Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers. Cell stem cell\| PubMed ID: 36787740	2023
Reversal of liver failure using a bioartificial liver device implanted with clinical-grade human-induced hepatocytes. Cell stem cell\| PubMed ID: 37059100	2023
Ex vivo factor VIII-modified proliferating human hepatocytes therapy for haemophilia A. Cell proliferation\| PubMed ID: 37199059	2023
Hepatocyte transplantation: The progress and the challenges. Hepatology communications\| PubMed ID: 37695736	2023
Progress in patient-derived liver cancer cell models: a step forward for precision medicine. Acta biochimica et biophysica Sinica\| PubMed ID: 37766458	2023
ZNT1 and Zn 2+ control TLR4 and PD-L1 endocytosis in macrophages to improve chemotherapy efficacy against liver tumor. Hepatology (Baltimore, Md.)\| PubMed ID: 37816045	2024
Preclinical efficacy and safety of encapsulated proliferating human hepatocyte organoids in treating liver failure. Cell stem cell\| PubMed ID: 38458193	2024
A spatiotemporal atlas of cholestatic injury and repair in mice. Nature genetics\| PubMed ID: 38627596	2024
A spatiotemporal atlas of mouse liver homeostasis and regeneration. Nature genetics\| PubMed ID: 38627598	2024
25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages. Immunity\| PubMed ID: 38640930	2024
Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases. Cell stem cell\| PubMed ID: 38772378	2024
Standard: Human gastric cancer organoids. Cell regeneration (London, England)\| PubMed ID: 39729207	2024
Standard: Human gastric organoids. Cell regeneration (London, England)\| PubMed ID: 39808364	2025
Author Correction: Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes. Cell research\| PubMed ID: 40148490	2025
A Microgel-Hydrogel Hybrid for Functional Compensation and Mechanical Stability in 3D Printed Cell-Dense Vascularized Liver Tissue. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 40223341	2025
Expansion of human hepatocytes and their application in three-dimensional culture and genetic manipulation. Nature protocols\| PubMed ID: 40715744	2025