Dwight D. Harris

Department of Surgery, Brown University

Affiliated withBrown University Rhode Island Hospital

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2025
Publication title Cited by 1	2025

Other Publications

Article	Year
Canagliflozin Improves Myocardial Perfusion, Fibrosis, and Function in a Swine Model of Chronic Myocardial Ischemia. Journal of the American Heart Association\| PubMed ID: 36583437	2023
Comparative Analysis of Normoxia- and Hypoxia-Modified Extracellular Vesicle Therapy in Function, Perfusion, and Collateralization in Chronically Ischemic Myocardium. International journal of molecular sciences\| PubMed ID: 36768399	2023
Sitagliptin therapy improves myocardial perfusion and arteriolar collateralization in chronically ischemic myocardium: A pilot study. Physiological reports\| PubMed ID: 37300400	2023
Impaired cardiac glycolysis and glycogen depletion are linked to poor myocardial outcomes in juvenile male swine with metabolic syndrome and ischemia. Physiological reports\| PubMed ID: 37537137	2023
Canagliflozin improves coronary microvascular vasodilation and increases absolute blood flow to the myocardium independent of angiogenesis. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 37604273	2023
Calpain inhibition decreases oxidative stress via mitochondrial regulation in a swine model of chronic myocardial ischemia. Free radical biology & medicine\| PubMed ID: 37748718	2023
Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardium. JTCVS open\| PubMed ID: 37808040	2023
Sodium-glucose co-transporter 2 inhibitor canagliflozin modulates myocardial metabolism and inflammation in a swine model for chronic myocardial ischemia. Surgery\| PubMed ID: 37940431	2024
Extracellular vesicle treatment partially reverts epigenetic alterations in chronically ischemic porcine myocardium. Vessel plus\| PubMed ID: 37982029	2023
Effects of canagliflozin on myocardial microvascular density, oxidative stress, and proteomic profile. Journal of molecular and cellular cardiology plus\| PubMed ID: 38188970	2023
Ischemic myocardial inflammatory signaling in starvation versus hypoxia-derived extracellular vesicles: A comparative analysis. JTCVS open\| PubMed ID: 38204622	2023
Proteomic Analysis and Sex-Specific Changes in Chronically Ischemic Swine Myocardium Treated with Sodium-Glucose Cotransporter-2 Inhibitor Canagliflozin. Journal of the American College of Surgeons\| PubMed ID: 38288953	2024
Role of Protein Kinase C in Metabolic Regulation of Coronary Endothelial Small Conductance Calcium-Activated Potassium Channels. Journal of the American Heart Association\| PubMed ID: 38293916	2024
Intramyocardial Injection of Hypoxia-Conditioned Extracellular Vesicles Modulates Response to Oxidative Stress in the Chronically Ischemic Myocardium. Bioengineering (Basel, Switzerland)\| PubMed ID: 38391611	2024
Crafting a Rigorous, Clinically Relevant Large Animal Model of Chronic Myocardial Ischemia: What Have We Learned in 20 Years? Methods and protocols\| PubMed ID: 38392691	2024
DPP-4 inhibitor sitagliptin treatment results in altered myocardial metabolic proteome and oxidative phosphorylation in a swine model of chronic myocardial ischemia. Physiological reports\| PubMed ID: 38472161	2024
Proteomic Profiling of SGLT-2 Inhibitor Canagliflozin in a Swine Model of Chronic Myocardial Ischemia. Biomedicines\| PubMed ID: 38540200	2024
Patients with uncontrolled hypertension subjected to cardiopulmonary bypass have altered coronary vasomotor responses to serotonin. Surgery\| PubMed ID: 38755032	2024
Cardioprotection in cardiovascular surgery. Basic research in cardiology\| PubMed ID: 38856733	2024
Effects of diet-induced metabolic syndrome on cardiac function and angiogenesis in response to the sodium-glucose cotransporter-2 inhibitor canagliflozin. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 38879117	2024
Metformin Preconditioning Augments Cardiac Perfusion and Performance in a Large Animal Model of Chronic Coronary Artery Disease. Annals of surgery\| PubMed ID: 39041226	2024
Dipeptidyl peptidase 4 inhibitor sitagliptin decreases myocardial fibrosis and modulates myocardial insulin signaling in a swine model of chronic myocardial ischemia. PloS one\| PubMed ID: 39074126	2024
Antineutrophil Cytoplasmic Antibody Vasculitis after Coronary Artery Bypass Grafting. Case reports in surgery\| PubMed ID: 39161946	2024
Comparative effects of canagliflozin and sitagliptin in chronically ischemic myocardium. Vessel plus\| PubMed ID: 39176133	2024
Intramyocardial injection of hypoxia-conditioned extracellular vesicles increases myocardial perfusion in a swine model of chronic coronary disease. JTCVS open\| PubMed ID: 39296447	2024
Gender, race, and ethnicity in lung cancer clinical trial participation: Analysis of 253,845 patients from 2002 to 2021. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 39349163	2025
Sodium-Glucose Cotransporter-2 Inhibition Normalizes Metabolic Derangements in the Ischemic Myocardium. The Journal of surgical research\| PubMed ID: 39437599	2024
Protein Kinase C-β Inhibition and Survival Signaling after Simulated Cardioplegic-Ischemia/Reperfusion in Nondiabetic and Diabetic Human Coronary Arterial Endothelial Cells. Journal of the American College of Surgeons\| PubMed ID: 39651752	2025
Semaglutide Improves Myocardial Perfusion and Performance in a Large Animal Model of Coronary Artery Disease. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 39665144	2025
Lab-grown, 3D extracellular matrix particles improve cardiac function and morphology in myocardial ischemia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 39705507	2025
Dipeptidyl peptidase-4 inhibitor linagliptin improves fibrosis, apoptosis, and cardiac function in a large animal model of chronic myocardial ischemia. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 40023609	2025
Sex-Specific Improvements in Myocardial Function and Angiogenesis with SGLT-2 Inhibitor Canagliflozin in a Swine Model of Metabolic Syndrome. International journal of molecular sciences\| PubMed ID: 40076513	2025
Linagliptin Modulation of Inflammation in Chronic Coronary Artery Disease. The Journal of surgical research\| PubMed ID: 40253935	2025
Linagliptin exerts a sex-specific effect on cardiac function, collateralization, and metabolism in a swine model of cardiometabolic disease. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 40324745	2025
Preoperative dementia in patients undergoing coronary artery bypass grafting: A propensity-matched analysis. Surgery\| PubMed ID: 40344991	2025
Canagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces lung fibrosis in left heart dysfunction. Asian cardiovascular & thoracic annals\| PubMed ID: 40605641	2025
Sodium-glucose Cotransporter-2 Canagliflozin's impact on cardiovascular disease in the setting of metabolic syndrome: A proteomic analysis. European journal of pharmacology\| PubMed ID: 40683440	2025
Sodium-glucose cotransporter 2 inhibition restores testicular microvascular perfusion via endothelial signaling in a large animal model of metabolic syndrome and heart failure. Vascular pharmacology\| PubMed ID: 40848868	2025
Targeting Mitochondrial Reactive Oxygen Species: JP4-039's Potential as a Cardiovascular Therapeutic. Journal of clinical medicine\| PubMed ID: 41010669	2025