Frank W. Sellke

Department of Surgery, Brown University

Affiliated withBrown University Rhode Island Hospital

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2025
Publication title Cited by 1	2025

Other Publications

Article	Year
Effect of thrombin fragment (TP508) on myocardial ischemia-reperfusion injury in hypercholesterolemic pigs. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 19372304	2009
Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19395857	2009
Altered coronary microvascular serotonin receptor expression after coronary artery bypass grafting with cardiopulmonary bypass. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 19660281	2010
Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion. Circulation\| PubMed ID: 19752371	2009
Large conductance calcium-activated potassium channels contribute to the reduced myogenic tone of peripheral microvasculature after cardiopulmonary bypass. The Journal of surgical research\| PubMed ID: 19765723	2009
Endothelin-1-induced contractile responses of human coronary arterioles via endothelin-A receptors and PKC-alpha signaling pathways. Surgery\| PubMed ID: 20079914	2010
Pharmacotherapy for end-stage coronary artery disease. Expert opinion on pharmacotherapy\| PubMed ID: 20088742	2010
Effect of dimerized thrombin fragment TP508 on acute myocardial ischemia reperfusion injury in hypercholesterolemic swine. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20460385	2010
Is hyperglycemia bad for the heart during acute ischemia? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 20542299	2010
Anti-angiogenic effect of high-dose resveratrol in a swine model of metabolic syndrome. Surgery\| PubMed ID: 20570307	2010
Effects of diabetes mellitus on VEGF-induced proliferation response in bone marrow derived endothelial progenitor cells. Journal of cardiac surgery\| PubMed ID: 20626511	2010
Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20702812	2010
Decreased contractile response to endothelin-1 of peripheral microvasculature from diabetic patients. Surgery\| PubMed ID: 20727565	2011
Temporal and spatial changes in collateral formation and function during chronic myocardial ischemia. Journal of the American College of Surgeons\| PubMed ID: 20729101	2010
Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on ischemic myocardium. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 20804993	2010
Effects of neuropeptide Y on collateral development in a swine model of chronic myocardial ischemia. Journal of molecular and cellular cardiology\| PubMed ID: 20826160	2010
Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia. Circulation\| PubMed ID: 20837905	2010
Effects of cardiopulmonary bypass on endothelin-1-induced contraction and signaling in human skeletal muscle microcirculation. Circulation\| PubMed ID: 20837906	2010
Effect of thrombin fragment (TP508) on myocardial ischemia reperfusion injury in a model of type 1 diabetes mellitus. Circulation\| PubMed ID: 20837908	2010
Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on myocardial function and perfusion. Journal of cardiovascular pharmacology\| PubMed ID: 21233641	2011
In vitro and in vivo degradation of poly(D, L-lactide-co-glycolide)/amorphous calcium phosphate copolymer coated on metal stents. Journal of biomedical materials research. Part A\| PubMed ID: 21268237	2011
p38 MAPK-dependent small HSP27 and αB-crystallin phosphorylation in regulation of myocardial function following cardioplegic arrest. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21357508	2011
Chronic type II diabetes mellitus leads to changes in neuropeptide Y receptor expression and distribution in human myocardial tissue. European journal of pharmacology\| PubMed ID: 21549702	2011
Resveratrol modifies risk factors for coronary artery disease in swine with metabolic syndrome and myocardial ischemia. European journal of pharmacology\| PubMed ID: 21575630	2011
Improving glucose metabolism with resveratrol in a swine model of metabolic syndrome through alteration of signaling pathways in the liver and skeletal muscle. Archives of surgery (Chicago, Ill. : 1960)\| PubMed ID: 21739664	2011
Hypercholesterolemia and chronic ischemia alter myocardial responses to selective cyclooxygenase-2 inhibition. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 21762932	2011
Resveratrol supplementation abrogates pro-arteriogenic effects of intramyocardial vascular endothelial growth factor in a hypercholesterolemic swine model of chronic ischemia. Surgery\| PubMed ID: 21783219	2011
Chymase inhibition reduces infarction and matrix metalloproteinase-9 activation and attenuates inflammation and fibrosis after acute myocardial ischemia/reperfusion. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21795433	2011
Impaired contractile response of human peripheral arterioles to thromboxane A-2 after cardiopulmonary bypass. Surgery\| PubMed ID: 21801963	2011
Thromboxane-induced contractile response of human coronary arterioles is diminished after cardioplegic arrest. The Annals of thoracic surgery\| PubMed ID: 21871266	2011
High-fat diet alters prostanoid balance and perfusion in ischemic myocardium of naproxen-treated swine. Surgery\| PubMed ID: 21878235	2011
Rottlerin increases cardiac contractile performance and coronary perfusion through BKCa++ channel activation after cold cardioplegic arrest in isolated hearts. Circulation\| PubMed ID: 21911819	2011
Effects of cyclooxygenase inhibition on cardiovascular function in a hypercholesterolemic swine model of chronic ischemia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 22037194	2012
Myocardial therapeutic angiogenesis: a review of the state of development and future obstacles. Expert review of cardiovascular therapy\| PubMed ID: 22059795	2011
Overfed Ossabaw swine with early stage metabolic syndrome have normal coronary collateral development in response to chronic ischemia. Basic research in cardiology\| PubMed ID: 22231675	2012
Effects of alcohol on pericardial adhesion formation in hypercholesterolemic swine. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 22244558	2012
Essential roles of Raf/extracellular signal-regulated kinase/mitogen-activated protein kinase pathway, YY1, and Ca2+ influx in growth arrest of human vascular smooth muscle cells by bilirubi... The Journal of biological chemistry\| PubMed ID: 22262839	2012
Preserving cardiac and pulmonary function after cardiopulmonary bypass: effects of reactive nitrogen species. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 22291423	2012
Hypothermia severely effects performance of nitinol-based endovascular grafts in vitro. The Annals of thoracic surgery\| PubMed ID: 22385821	2012
Cardioprotective effects of red wine and vodka in a model of endothelial dysfunction. The Journal of surgical research\| PubMed ID: 22748601	2012
Decreased coronary microvascular reactivity after cardioplegic arrest in patients with uncontrolled diabetes mellitus. Surgery\| PubMed ID: 22828147	2012
Resveratrol preserves myocardial function and perfusion in remote nonischemic myocardium in a swine model of metabolic syndrome. Journal of the American College of Surgeons\| PubMed ID: 22867714	2012
Vodka and wine consumption in a swine model of metabolic syndrome alters insulin signaling pathways in the liver and skeletal muscle. Surgery\| PubMed ID: 22938901	2012
Effects of red wine and vodka on collateral-dependent perfusion and cardiovascular function in hypercholesterolemic swine. Circulation\| PubMed ID: 22965995	2012
Changes in microvascular reactivity after cardiopulmonary bypass in patients with poorly controlled versus controlled diabetes. Circulation\| PubMed ID: 22965996	2012
Mechanism for reduced pericardial adhesion formation in hypercholesterolemic swine supplemented with alcohol. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 22991457	2013
Atorvastatin increases oxidative stress and modulates angiogenesis in Ossabaw swine with the metabolic syndrome. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 22995723	2012
Metformin alters the insulin signaling pathway in ischemic cardiac tissue in a swine model of metabolic syndrome. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 23083540	2013
Does resveratrol improve insulin signaling in chronically ischemic myocardium? The Journal of surgical research\| PubMed ID: 23622724	2013
Alcohol consumption improves insulin signaling in the myocardium. Surgery\| PubMed ID: 23889958	2013
Altered expression and activation of mitogen-activated protein kinases in diabetic heart during cardioplegic arrest and cardiopulmonary bypass. Surgery\| PubMed ID: 23972649	2013
Oxidative stress improves coronary endothelial function through activation of the pro-survival kinase AMPK. Aging\| PubMed ID: 24018842	2013
Ethanol promotes arteriogenesis and restores perfusion to chronically ischemic myocardium. Circulation\| PubMed ID: 24030397	2013
Altered apoptosis-related signaling after cardioplegic arrest in patients with uncontrolled type 2 diabetes mellitus. Circulation\| PubMed ID: 24030399	2013
Arterial territory-specific phosphorylated retinoblastoma protein species and CDK2 promote differences in the vascular smooth muscle cell response to mitogens. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24240190	2014
Rapamycin treatment of healthy pigs subjected to acute myocardial ischemia-reperfusion injury attenuates cardiac functions and increases myocardial necrosis. The Annals of thoracic surgery\| PubMed ID: 24266948	2014
Resveratrol regulates autophagy signaling in chronically ischemic myocardium. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 24267781	2014
Universal definition of perioperative bleeding in adult cardiac surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 24332097	2014
Microvascular notch signaling is upregulated in response to vascular endothelial growth factor and chronic myocardial ischemia. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 24366099	2014
Alcohol consumption mitigates apoptosis and mammalian target of rapamycin signaling in myocardium. Journal of the American College of Surgeons\| PubMed ID: 24680568	2014
Ethanol promotes new vessel growth in remote nonischemic myocardium. The Journal of surgical research\| PubMed ID: 24961889	2015
Metformin mitigates apoptosis in ischemic myocardium. The Journal of surgical research\| PubMed ID: 24969550	2014
Metabolic syndrome impairs notch signaling and promotes apoptosis in chronically ischemic myocardium. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 25037620	2014
Investigating the effects of resveratrol on chronically ischemic myocardium in a swine model of metabolic syndrome: a proteomics analysis. Journal of medicinal food\| PubMed ID: 25089828	2015
Dabigatran-related coagulopathy: when can we assume the effect has "worn off"? The American journal of emergency medicine\| PubMed ID: 25239691	2014
Differential effects of atorvastatin on autophagy in ischemic and nonischemic myocardium in Ossabaw swine with metabolic syndrome. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 25240527	2014
Preoperative gene expression may be associated with neurocognitive decline after cardiopulmonary bypass. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 25483902	2015
Atorvastatin regulates apoptosis in chronically ischemic myocardium. Journal of cardiac surgery\| PubMed ID: 25511504	2015
Rottlerin-induced BKCa channel activation impairs specific contractile responses and promotes vasodilation. The Annals of thoracic surgery\| PubMed ID: 25527424	2015
Ca(2+)-activated K(+) channels as therapeutic targets for myocardial and vascular protection. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 25746520	2015
Attenuation of inflammatory responses by hydrogen sulfide (H₂S) in ischemia/reperfusion injury. Methods in enzymology\| PubMed ID: 25747478	2015
The effect of statins on perioperative inflammation in cardiac and thoracic surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 25791954	2015
Calpain inhibition decreases myocardial apoptosis in a swine model of chronic myocardial ischemia. Surgery\| PubMed ID: 25991048	2015
Oxidative Stress Biomarkers and Incidence of Postoperative Atrial Fibrillation in the Omega-3 Fatty Acids for Prevention of Postoperative Atrial Fibrillation (OPERA) Trial. Journal of the American Heart Association\| PubMed ID: 25994442	2015
Antioxidant Therapy: Is it your Gateway to Improved Cardiovascular Health? Pharmaceutica analytica acta\| PubMed ID: 26005589	2015
Differential impairment of adherens-junction expression/phosphorylation after cardioplegia in diabetic versus non-diabetic patients. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 26069241	2016
New continuous-flow total artificial heart and vascular permeability. The Journal of surgical research\| PubMed ID: 26188957	2015
Alcohol and the Heart: A Proteomics Analysis of Pericardium and Myocardium in a Swine Model of Myocardial Ischemia. The Annals of thoracic surgery\| PubMed ID: 26242211	2015
Inactivation of Endothelial Small/Intermediate Conductance of Calcium-Activated Potassium Channels Contributes to Coronary Arteriolar Dysfunction in Diabetic Patients. Journal of the American Heart Association\| PubMed ID: 26304940	2015
Calpain inhibition improves collateral-dependent perfusion in a hypercholesterolemic swine model of chronic myocardial ischemia. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 26478238	2016
Calpains and Coronary Vascular Disease. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 26489456	2016
Atrial Fibrillation, Neurocognitive Decline and Gene Expression After Cardiopulmonary Bypass. Brazilian journal of cardiovascular surgery\| PubMed ID: 26735598	2015
Endothelial ROS and Impaired Myocardial Oxygen Consumption in Sepsis-induced Cardiac Dysfunction. Journal of intensive and critical care\| PubMed ID: 27135058	2016
Alcohol modulates autophagy and apoptosis in pig liver tissue. The Journal of surgical research\| PubMed ID: 27338546	2016
Reversal of Dabigatran with Idarucizumab. Expert review of cardiovascular therapy\| PubMed ID: 27362456	2016
Glycogen Synthase Kinase 3β Inhibition Improves Myocardial Angiogenesis and Perfusion in a Swine Model of Metabolic Syndrome. Journal of the American Heart Association\| PubMed ID: 27405812	2016
Why don't things happen the same way every time? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 27717493	2016
Role of Calpain in Pathogenesis of Human Disease Processes. Journal of nature and science\| PubMed ID: 27747292	2016
Effects of diabetes and cardiopulmonary bypass on expression of adherens junction proteins in human peripheral tissue. Surgery\| PubMed ID: 27838104	2017
Calpain inhibition modulates glycogen synthase kinase 3β pathways in ischemic myocardium: A proteomic and mechanistic analysis. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 27986275	2017
Calpain inhibition decreases inflammatory protein expression in vessel walls in a model of chronic myocardial ischemia. Surgery\| PubMed ID: 28024857	2017
Highlights of the American Heart Association Scientific Sessions 2016. Circulation\| PubMed ID: 28028063	2017
Mitochondrial redox plays a critical role in the paradoxical effects of NAPDH oxidase-derived ROS on coronary endothelium. Cardiovascular research\| PubMed ID: 28088753	2017
Massive left atrial calcification: a case report and review of the literature. General thoracic and cardiovascular surgery\| PubMed ID: 28176173	2017
Diabetes Upregulation of Cyclooxygenase 2 Contributes to Altered Coronary Reactivity After Cardiac Surgery. The Annals of thoracic surgery\| PubMed ID: 28223053	2017
Effects of Alcohol on Postoperative Adhesion Formation in Ischemic Myocardium and Pericardium. The Annals of thoracic surgery\| PubMed ID: 28262301	2017
Alcohol attenuates myocardial ischemic injury. Surgery\| PubMed ID: 28602493	2017
Novel molecular targets for coronary angiogenesis and ischemic heart disease. Coronary artery disease\| PubMed ID: 28678145	2017
Idarucizumab for Dabigatran Reversal - Full Cohort Analysis. The New England journal of medicine\| PubMed ID: 28693366	2017
Diabetes and Cardioplegia. Journal of nature and science\| PubMed ID: 28758150	2017
Cyclooxygenase 2 contributes to bradykinin-induced microvascular responses in peripheral arterioles after cardiopulmonary bypass. The Journal of surgical research\| PubMed ID: 28985857	2017
When in doubt, look to see what works in nature. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 28992964	2018
Bilateral Versus Single Internal Mammary Artery Bypass Grafting: Do We Have the Answer? Circulation\| PubMed ID: 29084777	2017
Predictors of patient radiation exposure during transcatheter aortic valve replacement. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions\| PubMed ID: 29280551	2018
Decreased coronary arteriolar response to K channel opener after cardioplegic arrest in diabetic patients. Molecular and cellular biochemistry\| PubMed ID: 29305679	2018
Surprises happen all the time. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29331179	2018
Subcellular Reactive Oxygen Species (ROS) in Cardiovascular Pathophysiology. Antioxidants (Basel, Switzerland)\| PubMed ID: 29337890	2018
Perspectives on Incentive Spirometry Utility and Patient Protocols. Respiratory care\| PubMed ID: 29362216	2018
Incentive Spirometry Adherence: A National Survey of Provider Perspectives. Respiratory care\| PubMed ID: 29362219	2018
Do radiopaque markers make a difference after coronary artery bypass grafting? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29370906	2018
Glycogen synthase kinase 3β inhibition reduces mitochondrial oxidative stress in chronic myocardial ischemia. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29523407	2018
Continuous Glucose Monitoring in the Cardiac ICU: Current Use and Future Directions. Clinical medicine research\| PubMed ID: 29683136	2017
Decreased contractile response of peripheral arterioles to serotonin after CPB in patients with diabetes. Surgery\| PubMed ID: 29759300	2018
Extracellular Vesicle Injection Improves Myocardial Function and Increases Angiogenesis in a Swine Model of Chronic Ischemia. Journal of the American Heart Association\| PubMed ID: 29895586	2018
Enhanced coronary arteriolar contraction to vasopressin in patients with diabetes after cardiac surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30057184	2018
Impaired coronary contraction to phenylephrine after cardioplegic arrest in diabetic patients. The Journal of surgical research\| PubMed ID: 30100044	2018
Financial Impact of Incentive Spirometry. Inquiry : a journal of medical care organization, provision and financing\| PubMed ID: 30175643	2018
Comparison of Incidence, Predictors, and Outcomes of Early Infective Endocarditis after Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in the United States. The American journal of cardiology\| PubMed ID: 30292332	2018
Impact of Packed Red Blood Cell and Platelet Transfusions in Patients Undergoing Dissection Repair. The Journal of surgical research\| PubMed ID: 30463739	2018
Relationship of mildly increased albuminuria and coronary artery revascularization outcomes in patients with diabetes. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions\| PubMed ID: 30467952	2019
Association Between Red Blood Cell Transfusion and Clinical Outcomes Among Patients Undergoing Transcatheter Aortic Valve Replacement. The Annals of thoracic surgery\| PubMed ID: 30552884	2019
Emphysema: A Potential Risk Factor for Subarachnoid Hemorrhage and Ruptured Aortic Aneurysm. Stroke\| PubMed ID: 30885079	2019
Effect of an Incentive Spirometer Patient Reminder After Coronary Artery Bypass Grafting: A Randomized Clinical Trial. JAMA surgery\| PubMed ID: 30969332	2019
Trends and outcomes of red blood cell transfusion in patients undergoing transcatheter aortic valve replacement in the United States. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31014667	2020
Transatlantic Editorial: Attrition of the cardiothoracic surgeon-scientist: definition of the problem and remedial strategies. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 31199476	2019
Transatlantic Editorial: Attrition of the Cardiothoracic Surgeon-Scientist: Definition of the Problem and Remedial Strategies. The Annals of thoracic surgery\| PubMed ID: 31208650	2019
Attrition of the cardiothoracic surgeon-scientist: Definition of the problem and remedial strategies. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31208802	2019
Increased coronary arteriolar contraction to serotonin in juvenile pigs with metabolic syndrome. Molecular and cellular biochemistry\| PubMed ID: 31352610	2019
Extracellular Vesicles Promote Arteriogenesis in Chronically Ischemic Myocardium in the Setting of Metabolic Syndrome. Journal of the American Heart Association\| PubMed ID: 31354010	2019
Utilization of Left Ventricular Assist Devices in Vulnerable Adults Across Medicaid Expansion. The Journal of surgical research\| PubMed ID: 31377490	2019
Skeletal muscle microvasculature response to β-adrenergic stimuli is diminished with cardiac surgery. Surgery\| PubMed ID: 31493902	2020
Jostling with jargon. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31703895	2020
Commentary: Hyperglycemia during myocardial infarction: Can sound waves improve outcomes? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31757457	2021
Robust effect of metabolic syndrome on major metabolic pathways in the myocardium. PloS one\| PubMed ID: 31790488	2019
Metabolomics and the pig model reveal aberrant cardiac energy metabolism in metabolic syndrome. Scientific reports\| PubMed ID: 32103083	2020
Swine Disease Models for Optimal Vascular Engineering. Annual review of biomedical engineering\| PubMed ID: 32119784	2020
Commentary: Del Nido cardioplegic solution: Is it really better than any other? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32122577	2021
Lower preoperative hematocrit, longer hospital stay, and neurocognitive decline after cardiac surgery. Surgery\| PubMed ID: 32178865	2020
Metabolic regulation of endothelial SK channels and human coronary microvascular function. International journal of cardiology\| PubMed ID: 32199682	2020
Cardiac involvement in COVID-19 patients: Risk factors, predictors, and complications: A review. Journal of cardiac surgery\| PubMed ID: 32306491	2020
Serum alpha-1 antitrypsin in acute ischemic stroke: A prospective pilot study. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia\| PubMed ID: 32327380	2020
Calpain inhibition decreases myocardial fibrosis in chronically ischemic hypercholesterolemic swine. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32359903	2022
The urgent need for integrated science to fight COVID-19 pandemic and beyond. Journal of translational medicine\| PubMed ID: 32430070	2020
The predictive role of circulating telomerase and vitamin D for long-term survival in patients undergoing coronary artery bypass grafting surgery (CABG). PloS one\| PubMed ID: 32790742	2020
Intravenous injection of extracellular vesicles to treat chronic myocardial ischemia. PloS one\| PubMed ID: 32915887	2020
Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 33086873	2020
Cardiac Surgery Utilization Across Vulnerable Persons After Medicaid Expansion. The Annals of thoracic surgery\| PubMed ID: 33188751	2021
Myocardial Contractile Reserve and Mortality in Patients With Severe Aortic Stenosis With Impaired Left Ventricular Function Who Underwent Transcatheter Aortic Valve Implantation. The American journal of cardiology\| PubMed ID: 33248116	2021
Transcatheter pulmonary valve replacement: an option for some but not for all. Journal of thoracic disease\| PubMed ID: 33282344	2020
The Relationship Between Reactive Oxygen Species and Endothelial Cell Metabolism. Frontiers in chemistry\| PubMed ID: 33330380	2020
Secondary prevention after coronary artery bypass grafting: Anticoagulation and antiplatelet therapy is only one factor. Journal of cardiac surgery\| PubMed ID: 33506999	2021
Post-Cardiac Surgery Atrial Fibrillation: Risks, Mechanisms, Prevention, and Management. Cardiac electrophysiology clinics\| PubMed ID: 33516391	2021
Reply: Medicolegal research: A key to the locked door of patient expectations. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 33516460	2022
Effects of High Fat Versus Normal Diet on Extracellular Vesicle-Induced Angiogenesis in a Swine Model of Chronic Myocardial Ischemia. Journal of the American Heart Association\| PubMed ID: 33559477	2021
Corrigendum to "Utilization of Left Ventricular Assist Devices in Vulnerable Adults Across Medicaid Expansion": Journal of Surgical Research 243 (2019) 503-508/https://doi.org/10.1016/j.jss.... The Journal of surgical research\| PubMed ID: 33616073	2020
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy\| PubMed ID: 33634751	2021
Chronic Inhibition of mROS Protects Against Coronary Endothelial Dysfunction in Mice With Diabetes. Frontiers in cell and developmental biology\| PubMed ID: 33681229	2021
Mesenchymal stem cell-derived extracellular vesicles in the failing heart: past, present, and future. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 33861149	2021
Clinical Application of Novel Therapies for Coronary Angiogenesis: Overview, Challenges, and Prospects. International journal of molecular sciences\| PubMed ID: 33918396	2021
Interdisciplinary Approaches to COVID-19. Advances in experimental medicine and biology\| PubMed ID: 33973220	2021
Medical malpractice in heart transplantation from 1994 to 2019. Journal of cardiac surgery\| PubMed ID: 33982334	2021
International Scientific Collaboration Is Needed to Bridge Science to Society: USERN2020 Consensus Statement. SN comprehensive clinical medicine\| PubMed ID: 33997623	2021
Cardiac surgeons' concerns, perceptions, and responses during the COVID-19 pandemic. Journal of cardiac surgery\| PubMed ID: 34118080	2021
Inhibition of mitochondrial reactive oxygen species improves coronary endothelial function after cardioplegic hypoxia/reoxygenation. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 34274141	2022
Medical malpractice in aortic valve and mitral valve replacement surgery in North America. The Journal of cardiovascular surgery\| PubMed ID: 34338496	2022
probiotic induces Nrf2-mediated antioxidant signaling and eNOS expression resulting in improvement of myocardial diastolic function. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 34506225	2021
Coronary Artery Bypass Grafting With the Internal Thoracic Artery: A Great Operation With Some Unanswered Questions. JAMA cardiology\| PubMed ID: 34586360	2021
The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients. Scientific reports\| PubMed ID: 34611227	2021
Commentary: If it looks too good to be true, it probably is. JTCVS techniques\| PubMed ID: 34647071	2021
Increased Access to Cardiac Surgery Did Not Improve Outcomes: Early Look Into Medicaid Expansion. The Annals of thoracic surgery\| PubMed ID: 34678282	2022
Author Correction: The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients. Scientific reports\| PubMed ID: 34711865	2021
Glycemic control is not associated with neurocognitive decline after cardiac surgery. Journal of cardiac surgery\| PubMed ID: 34713498	2022
Rationale and design of the safe and timely antithrombotic removal - ticagrelor (STAR-T) trial: A prospective, multi-center, double-blind, randomized controlled trial evaluating reductions i... American heart journal\| PubMed ID: 34736855	2022
Extracellular vesicles improve diastolic function and substructure in normal and high-fat diet models of chronic myocardial ischemia. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 34756431	2022
Methylome of skeletal muscle tissue in patients with hypertension and diabetes undergoing cardiopulmonary bypass. Epigenomics\| PubMed ID: 34802257	2021
The impact of the American Association for Thoracic Surgery on National Institutes of Health grant funding for cardiothoracic surgeons. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 34809972	2023
The Heart Team for Coronary Revascularization Decisions: 2 Illustrative Cases. JACC. Case reports\| PubMed ID: 35199000	2022
Pequi Fruit Extract Increases Antioxidant Enzymes and Reduces Oxidants in Human Coronary Artery Endothelial Cells. Antioxidants (Basel, Switzerland)\| PubMed ID: 35326129	2022
Assessments of microvascular function in organ systems. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 35333121	2022
Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 35333122	2022
Antithrombotic drug removal from whole blood using Haemoadsorption with a porous polymer bead sorbent. European heart journal. Cardiovascular pharmacotherapy\| PubMed ID: 35657375	2022
Preoperative fibrinogen before the repair of type A aortic dissection: Are the results too good to be true?: Editorial comment on: Li J, Wu Q, Tang M, Shen Y, Qiu Z, Chen X, Chen X, Chen L. ... Journal of cardiac surgery\| PubMed ID: 35864816	2022
Commentary: How do you get your grant refunded? JTCVS open\| PubMed ID: 36003421	2022
Poorly controlled hypertension is associated with increased coronary myogenic tone in patients undergoing cardiac surgery with cardiopulmonary bypass. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36008180	2023
Extracellular vesicles modulate inflammatory signaling in chronically ischemic myocardium of swine with metabolic syndrome. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36028364	2023
Neurocognitive decline in cardiac surgery patients: What do we know? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36049967	2023
Estimating the causal effect of the Medicaid expansion on heart transplant volume with a differences-in-differences model. JTCVS open\| PubMed ID: 36172439	2022
Extracellular vesicle therapy attenuates antiangiogenic signaling in ischemic myocardium of swine with metabolic syndrome. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36244819	2023
Commentary: National Institutes of Health funding by thoracic surgeons: It is good to have a strong beacon rather than just a candle. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36344314	2024
Pulmonary hypertension associated with cardiopulmonary bypass and cardiac surgery. Journal of cardiac surgery\| PubMed ID: 36378925	2022
Canagliflozin Improves Myocardial Perfusion, Fibrosis, and Function in a Swine Model of Chronic Myocardial Ischemia. Journal of the American Heart Association\| PubMed ID: 36583437	2023
Did ethno-racial disparities in access to transcatheter aortic valve replacement change over time? JTCVS open\| PubMed ID: 36590742	2022
Reduction in mitochondrial ROS improves oxidative phosphorylation and provides resilience to coronary endothelium in non-reperfused myocardial infarction. Basic research in cardiology\| PubMed ID: 36639609	2023
Proteomic Assessment of Hypoxia-Pre-Conditioned Human Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicles Demonstrates Promise in the Treatment of Cardiovascular Disease. International journal of molecular sciences\| PubMed ID: 36675188	2023
Effect of Patient Sex on Neurocognitive Decline after Cardiac Surgery. Journal of the American College of Surgeons\| PubMed ID: 36727930	2023
Comparative Analysis of Normoxia- and Hypoxia-Modified Extracellular Vesicle Therapy in Function, Perfusion, and Collateralization in Chronically Ischemic Myocardium. International journal of molecular sciences\| PubMed ID: 36768399	2023
Visualization of cardiac uptake of bone marrow mesenchymal stem cell-derived extracellular vesicles after intramyocardial or intravenous injection in murine myocardial infarction. Physiological reports\| PubMed ID: 36967241	2023
One Billion hiPSC-Cardiomyocytes: Upscaling Engineered Cardiac Tissues to Create High Cell Density Therapies for Clinical Translation in Heart Regeneration. Bioengineering (Basel, Switzerland)\| PubMed ID: 37237658	2023
Sitagliptin therapy improves myocardial perfusion and arteriolar collateralization in chronically ischemic myocardium: A pilot study. Physiological reports\| PubMed ID: 37300400	2023
Clinical uses of epigenetics in cardiology and cardiothoracic surgery: an update. Epigenomics\| PubMed ID: 37309585	2023
Invited commentary on Kowalewski M, Pasierski M, Makhoul M, et al. Topical vancomycin for sternal wound infection prophylaxis. A systematic review and updated meta-analysis of over 40,000 ca... Surgery\| PubMed ID: 37414588	2023
Impaired cardiac glycolysis and glycogen depletion are linked to poor myocardial outcomes in juvenile male swine with metabolic syndrome and ischemia. Physiological reports\| PubMed ID: 37537137	2023
Canagliflozin improves coronary microvascular vasodilation and increases absolute blood flow to the myocardium independent of angiogenesis. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 37604273	2023
Calpain inhibition decreases oxidative stress via mitochondrial regulation in a swine model of chronic myocardial ischemia. Free radical biology & medicine\| PubMed ID: 37748718	2023
Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardium. JTCVS open\| PubMed ID: 37808040	2023
Acute protein kinase C beta inhibition preserves coronary endothelial function after cardioplegic hypoxia/reoxygenation. JTCVS open\| PubMed ID: 37808045	2023
Increased Coronary Contraction to Thromboxane A2 in Cardiac Surgery Patients With Poorly Controlled Hypertension. The Journal of surgical research\| PubMed ID: 37925953	2024
Sodium-glucose co-transporter 2 inhibitor canagliflozin modulates myocardial metabolism and inflammation in a swine model for chronic myocardial ischemia. Surgery\| PubMed ID: 37940431	2024
Extracellular vesicle treatment partially reverts epigenetic alterations in chronically ischemic porcine myocardium. Vessel plus\| PubMed ID: 37982029	2023
Interpretable machine learning-based predictive modeling of patient outcomes following cardiac surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 38040328	2025
History of Psychoactive Medication a Risk Factor for Neurocognitive Decline After Cardiac Surgery. The Journal of surgical research\| PubMed ID: 38070255	2024
Diabetic state of human coronary artery endothelial cells results in altered effects of bone mesenchymal stem cell-derived extracellular vesicles. Physiological reports\| PubMed ID: 38114067	2023
Clinical application and management of temporary mechanical circulatory support: A clinical consensus. Chinese medical journal\| PubMed ID: 38155554	2024
Effects of canagliflozin on myocardial microvascular density, oxidative stress, and proteomic profile. Journal of molecular and cellular cardiology plus\| PubMed ID: 38188970	2023
Ischemic myocardial inflammatory signaling in starvation versus hypoxia-derived extracellular vesicles: A comparative analysis. JTCVS open\| PubMed ID: 38204622	2023
Extracellular Vesicles' Role in Angiogenesis and Altering Angiogenic Signaling. Medical sciences (Basel, Switzerland)\| PubMed ID: 38249080	2024
Proteomic Analysis and Sex-Specific Changes in Chronically Ischemic Swine Myocardium Treated with Sodium-Glucose Cotransporter-2 Inhibitor Canagliflozin. Journal of the American College of Surgeons\| PubMed ID: 38288953	2024
Role of Protein Kinase C in Metabolic Regulation of Coronary Endothelial Small Conductance Calcium-Activated Potassium Channels. Journal of the American Heart Association\| PubMed ID: 38293916	2024
The Current State of Extracellular Matrix Therapy for Ischemic Heart Disease. Medical sciences (Basel, Switzerland)\| PubMed ID: 38390858	2024
Intramyocardial Injection of Hypoxia-Conditioned Extracellular Vesicles Modulates Response to Oxidative Stress in the Chronically Ischemic Myocardium. Bioengineering (Basel, Switzerland)\| PubMed ID: 38391611	2024
Crafting a Rigorous, Clinically Relevant Large Animal Model of Chronic Myocardial Ischemia: What Have We Learned in 20 Years? Methods and protocols\| PubMed ID: 38392691	2024
DPP-4 inhibitor sitagliptin treatment results in altered myocardial metabolic proteome and oxidative phosphorylation in a swine model of chronic myocardial ischemia. Physiological reports\| PubMed ID: 38472161	2024
Exploring Electrospun Scaffold Innovations in Cardiovascular Therapy: A Review of Electrospinning in Cardiovascular Disease. Bioengineering (Basel, Switzerland)\| PubMed ID: 38534492	2024
Proteomic Profiling of SGLT-2 Inhibitor Canagliflozin in a Swine Model of Chronic Myocardial Ischemia. Biomedicines\| PubMed ID: 38540200	2024
Gastrointestinal complications after cardiac surgery. Trauma surgery & acute care open\| PubMed ID: 38616788	2024
Coronary Microvascular Dysfunction: A Guide for Clinicians. The American journal of medicine\| PubMed ID: 38723930	2024
Patients with uncontrolled hypertension subjected to cardiopulmonary bypass have altered coronary vasomotor responses to serotonin. Surgery\| PubMed ID: 38755032	2024
Lack of cardiac benefit after intramyocardial or intravenous injection of mesenchymal stem cell-derived extracellular vesicles supports the need for optimized cardiac delivery. Vessel plus\| PubMed ID: 38812773	2023
Cardioprotection in cardiovascular surgery. Basic research in cardiology\| PubMed ID: 38856733	2024
Effects of diet-induced metabolic syndrome on cardiac function and angiogenesis in response to the sodium-glucose cotransporter-2 inhibitor canagliflozin. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 38879117	2024
Risk Factors for Heart Failure Readmission After Cardiac Surgery. JACC. Advances\| PubMed ID: 38938350	2023
Strategies to attenuate maladaptive inflammatory response associated with cardiopulmonary bypass. Frontiers in surgery\| PubMed ID: 39022594	2024
Metformin Preconditioning Augments Cardiac Perfusion and Performance in a Large Animal Model of Chronic Coronary Artery Disease. Annals of surgery\| PubMed ID: 39041226	2024
Dipeptidyl peptidase 4 inhibitor sitagliptin decreases myocardial fibrosis and modulates myocardial insulin signaling in a swine model of chronic myocardial ischemia. PloS one\| PubMed ID: 39074126	2024
Comparative effects of canagliflozin and sitagliptin in chronically ischemic myocardium. Vessel plus\| PubMed ID: 39176133	2024
Intramyocardial injection of hypoxia-conditioned extracellular vesicles increases myocardial perfusion in a swine model of chronic coronary disease. JTCVS open\| PubMed ID: 39296447	2024
Gender, race, and ethnicity in lung cancer clinical trial participation: Analysis of 253,845 patients from 2002 to 2021. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 39349163	2025
Bleeding After Cardiovascular Surgery: A Continuing Problem. Circulation\| PubMed ID: 39432577	2024
Sodium-Glucose Cotransporter-2 Inhibition Normalizes Metabolic Derangements in the Ischemic Myocardium. The Journal of surgical research\| PubMed ID: 39437599	2024
Female patients exhibit altered vasopressin-induced coronary microvascular contractile response and molecular signaling following cardiac surgery. American journal of surgery\| PubMed ID: 39509937	2025
Protein Kinase C-β Inhibition and Survival Signaling after Simulated Cardioplegic-Ischemia/Reperfusion in Nondiabetic and Diabetic Human Coronary Arterial Endothelial Cells. Journal of the American College of Surgeons\| PubMed ID: 39651752	2025
Semaglutide Improves Myocardial Perfusion and Performance in a Large Animal Model of Coronary Artery Disease. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 39665144	2025
Lab-grown, 3D extracellular matrix particles improve cardiac function and morphology in myocardial ischemia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 39705507	2025
Renal Failure in Type A Aortic Dissection Repair: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis. The Annals of thoracic surgery\| PubMed ID: 39725252	2025
The Role of Preoperative Chronic Hypertension in Neurocognitive Decline after Cardiac Surgery: A Retrospective Cohort Study. Brazilian journal of cardiovascular surgery\| PubMed ID: 39937691	2025
Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension. Biomedicines\| PubMed ID: 40002822	2025
Dipeptidyl peptidase-4 inhibitor linagliptin improves fibrosis, apoptosis, and cardiac function in a large animal model of chronic myocardial ischemia. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 40023609	2025
Sex-Specific Improvements in Myocardial Function and Angiogenesis with SGLT-2 Inhibitor Canagliflozin in a Swine Model of Metabolic Syndrome. International journal of molecular sciences\| PubMed ID: 40076513	2025
Developments in Extracellular Matrix-Based Angiogenesis Therapy for Ischemic Heart Disease: A Review of Current Strategies, Methodologies and Future Directions. Biotech (Basel (Switzerland))\| PubMed ID: 40227326	2025
Linagliptin Modulation of Inflammation in Chronic Coronary Artery Disease. The Journal of surgical research\| PubMed ID: 40253935	2025
Mitochondria-targeted ROS scavenger JP4-039 improves cardiac function in a post-myocardial infarction animal model and induces angiogenesis in vitro. PloS one\| PubMed ID: 40273045	2025
Macrophage Proangiogenic VEGF-A Is Required for Inflammatory Arteriogenesis During Vascular Injury. Biomedicines\| PubMed ID: 40299401	2025
Linagliptin exerts a sex-specific effect on cardiac function, collateralization, and metabolism in a swine model of cardiometabolic disease. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 40324745	2025
Preoperative dementia in patients undergoing coronary artery bypass grafting: A propensity-matched analysis. Surgery\| PubMed ID: 40344991	2025
Age-specific Increase in vasopressin-induced Coronary Microvascular Contractile Response in Patients Undergoing Cardiac Surgery. Annals of surgery\| PubMed ID: 40525297	2025
Canagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces lung fibrosis in left heart dysfunction. Asian cardiovascular & thoracic annals\| PubMed ID: 40605641	2025
Impaired contractile response of human peripheral arterioles to angiotensin II after cardiopulmonary bypass. Surgery\| PubMed ID: 40651273	2025
Sodium-glucose Cotransporter-2 Canagliflozin's impact on cardiovascular disease in the setting of metabolic syndrome: A proteomic analysis. European journal of pharmacology\| PubMed ID: 40683440	2025
Sodium-glucose cotransporter 2 inhibition restores testicular microvascular perfusion via endothelial signaling in a large animal model of metabolic syndrome and heart failure. Vascular pharmacology\| PubMed ID: 40848868	2025
Targeting Mitochondrial Reactive Oxygen Species: JP4-039's Potential as a Cardiovascular Therapeutic. Journal of clinical medicine\| PubMed ID: 41010669	2025