Robert A. Britton

Department of Molecular Virology and Microbiology, Baylor College of Medicine

Affiliated withBaylor College of Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
The early response to acid shock in Lactobacillus reuteri involves the ClpL chaperone and a putative cell wall-altering esterase. Applied and environmental microbiology\| PubMed ID: 17449683	2007
Genomic and genetic characterization of the bile stress response of probiotic Lactobacillus reuteri ATCC 55730. Applied and environmental microbiology\| PubMed ID: 18245259	2008
Probiotics and gastrointestinal infections. Interdisciplinary perspectives on infectious diseases\| PubMed ID: 19277100	2008
Cyclopropane fatty acid synthase mutants of probiotic human-derived Lactobacillus reuteri are defective in TNF inhibition. Gut microbes\| PubMed ID: 21637024	2011
Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling. PloS one\| PubMed ID: 22384111	2012
Humanized microbiota mice as a model of recurrent Clostridium difficile disease. Microbiome\| PubMed ID: 26289776	2015
Intestinal microbial communities associated with acute enteric infections and disease recovery. Microbiome\| PubMed ID: 26395244	2015
Prebiotic and Probiotic Regulation of Bone Health: Role of the Intestine and its Microbiome. Current osteoporosis reports\| PubMed ID: 26419466	2015
Cultivation of stable, reproducible microbial communities from different fecal donors using minibioreactor arrays (MBRAs). Microbiome\| PubMed ID: 26419531	2015
Lactobacillus reuteri 6475 Increases Bone Density in Intact Females Only under an Inflammatory Setting. PloS one\| PubMed ID: 27058036	2016
YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit. Nucleic acids research\| PubMed ID: 27484475	2016
MiniBioReactor Arrays (MBRAs) as a Tool for Studying C. difficile Physiology in the Presence of a Complex Community. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27507346	2016
Mechanisms of cross-talk between the diet, the intestinal microbiome, and the undernourished host. Gut microbes\| PubMed ID: 27918230	2017
The impact of recent improvements in cryo-electron microscopy technology on the understanding of bacterial ribosome assembly. Nucleic acids research\| PubMed ID: 28180306	2017
Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation. Molecular systems biology\| PubMed ID: 28373240	2017
Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis. Infection and immunity\| PubMed ID: 28760934	2017
Gut Microbiota and Bone Health. Advances in experimental medicine and biology\| PubMed ID: 29101651	2017
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice. mSphere\| PubMed ID: 29299532	2018
Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice. International journal of molecular sciences\| PubMed ID: 29438346	2018
Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids. eLife\| PubMed ID: 29580380	2018
Protective role of commensal bacteria in Sjögren Syndrome. Journal of autoimmunity\| PubMed ID: 29934134	2018
The role of trehalose in the global spread of epidemic Clostridium difficile. Gut microbes\| PubMed ID: 30118389	2019
Genome alterations associated with improved transformation efficiency in Lactobacillus reuteri. Microbial cell factories\| PubMed ID: 30176942	2018
Body Mass Index as a Determinant of Systemic Exposure to Gallotannin Metabolites during 6-Week Consumption of Mango (Mangifera indica L.) and Modulation of Intestinal Microbiota in Lean and ... Molecular nutrition & food research\| PubMed ID: 30427574	2019
Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder. Neuron\| PubMed ID: 30522820	2019
Probiotic Lactobacillus reuteri Prevents Postantibiotic Bone Loss by Reducing Intestinal Dysbiosis and Preventing Barrier Disruption. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 30690795	2019
Degradation-resistant trehalose analogues block utilization of trehalose by hypervirulent Clostridioides difficile. Chemical communications (Cambridge, England)\| PubMed ID: 30968891	2019
Human Intestinal Enteroids With Inducible Neurogenin-3 Expression as a Novel Model of Gut Hormone Secretion. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 31029854	2019
Role of Era in assembly and homeostasis of the ribosomal small subunit. Nucleic acids research\| PubMed ID: 31265110	2019
Beneficial effects of Lactobacillus reuteri 6475 on bone density in male mice is dependent on lymphocytes. Scientific reports\| PubMed ID: 31605025	2019
Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide. Investigative ophthalmology & visual science\| PubMed ID: 31618426	2019
Scales of persistence: transmission and the microbiome. Current opinion in microbiology\| PubMed ID: 31629296	2019
The gut-eye-lacrimal gland-microbiome axis in Sjögren Syndrome. The ocular surface\| PubMed ID: 31644955	2020
Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate. Nucleic acids research\| PubMed ID: 31665744	2019
Adaptation of the Gut Microbiota to Modern Dietary Sugars and Sweeteners. Advances in nutrition (Bethesda, Md.)\| PubMed ID: 31696209	2020
Characterizing how probiotic 6475 and lactobacillic acid mediate suppression of osteoclast differentiation. Bone reports\| PubMed ID: 31763377	2019
Degradation of the Incretin Hormone Glucagon-Like Peptide-1 (GLP-1) by Enterococcus faecalis Metalloprotease GelE. mSphere\| PubMed ID: 32051237	2020
Post-antibiotic gut dysbiosis-induced trabecular bone loss is dependent on lymphocytes. Bone\| PubMed ID: 32061677	2020
Discovery of a bacterial peptide as a modulator of GLP-1 and metabolic disease. Scientific reports\| PubMed ID: 32188864	2020
Human intestinal enteroids as a model of -induced enteritis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 32223302	2020
Enhancing responsiveness of human jejunal enteroids to host and microbial stimuli. The Journal of physiology\| PubMed ID: 32428244	2020
Microbiota in vitro modulated with polyphenols shows decreased colonization resistance against Clostridioides difficile but can neutralize cytotoxicity. Scientific reports\| PubMed ID: 32433519	2020
Probiotics: Promise, Evidence, and Hope. Gastroenterology\| PubMed ID: 32531290	2020
Challenges and Pitfalls in the Engineering of Human Interleukin 22 (hIL-22) Secreting . Frontiers in bioengineering and biotechnology\| PubMed ID: 32582668	2020
Identification of Simplified Microbial Communities That Inhibit Clostridioides difficile Infection through Dilution/Extinction. mSphere\| PubMed ID: 32727857	2020
Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut-Brain Axis. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 32795610	2021
Reuterin disrupts metabolism and pathogenicity through reactive oxygen species generation. Gut microbes\| PubMed ID: 32804011	2020
Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence. NPJ systems biology and applications\| PubMed ID: 33082337	2020
Rotavirus induces intercellular calcium waves through ADP signaling. Science (New York, N.Y.)\| PubMed ID: 33214249	2020
Fusobacteriumnucleatum Adheres to Clostridioides difficile via the RadD Adhesin to Enhance Biofilm Formation in Intestinal Mucus. Gastroenterology\| PubMed ID: 33227279	2021
Probiotics and the Microbiome-How Can We Help Patients Make Sense of Probiotics? Gastroenterology\| PubMed ID: 33307023	2021
Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation. mBio\| PubMed ID: 33653893	2021
The metabolic profile of Bifidobacterium dentium reflects its status as a human gut commensal. BMC microbiology\| PubMed ID: 34030655	2021
Differentially Expressed Gene Pathways in the Conjunctiva of Sjögren Syndrome Keratoconjunctivitis Sicca. Frontiers in immunology\| PubMed ID: 34349764	2021
Drivers of transcriptional variance in human intestinal epithelial organoids. Physiological genomics\| PubMed ID: 34612061	2021
Distinct gene expression profiles between human preterm-derived and adult-derived intestinal organoids exposed to : a pilot study. Gut\| PubMed ID: 34921063	2021
RbgA ensures the correct timing in the maturation of the 50S subunits functional sites. Nucleic acids research\| PubMed ID: 35141754	2022
Gut-derived butyrate suppresses ocular surface inflammation. Scientific reports\| PubMed ID: 35296712	2022
Gut Microbiota From Sjögren syndrome Patients Causes Decreased T Regulatory Cells in the Lymphoid Organs and Desiccation-Induced Corneal Barrier Disruption in Mice. Frontiers in medicine\| PubMed ID: 35355610	2022
Author Correction: Gut-derived butyrate suppresses ocular surface inflammation. Scientific reports\| PubMed ID: 35449441	2022
Systems biology approach to functionally assess the pangenome reveals genetic diversity with discriminatory power. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 35476524	2022
A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 36595694	2023
Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling. bioRxiv : the preprint server for biology\| PubMed ID: 36945649	2023
Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling. Gut microbes\| PubMed ID: 37698879	2023
Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model. NPJ biofilms and microbiomes\| PubMed ID: 37985659	2023
Complete list of canonical post-transcriptional modifications in the ribosome and their link to RbgA driven large subunit assembly. bioRxiv : the preprint server for biology\| PubMed ID: 38765983	2024
Taking Microbiome Science to the Next Level: Recommendations to Advance the Emerging Field of Microbiome-Based Therapeutics and Diagnostics. Gastroenterology\| PubMed ID: 38815708	2024
A complementary metaproteomic approach to interrogate microbiome cultivated from clinical colon biopsies. Proteomics\| PubMed ID: 38824665	2024
Complete list of canonical post-transcriptional modifications in the Bacillus subtilis ribosome and their link to RbgA driven large subunit assembly. Nucleic acids research\| PubMed ID: 39036956	2024
A novel system to culture human intestinal organoids under physiological oxygen content to study microbial-host interaction. PloS one\| PubMed ID: 39052651	2024
Emerging ribotypes have divergent metabolic phenotypes. bioRxiv : the preprint server for biology\| PubMed ID: 39185189	2024
Bacteroides ovatus alleviates dysbiotic microbiota-induced graft-versus-host disease. Cell host & microbe\| PubMed ID: 39214085	2024
promotes the expression and secretion of enteroendocrine- and enterocyte-derived hormones. bioRxiv : the preprint server for biology\| PubMed ID: 39257733	2024
Insights into human norovirus cultivation in human intestinal enteroids. mSphere\| PubMed ID: 39404443	2024
Early life microbial succession in the gut follows common patterns in humans across the globe. Nature communications\| PubMed ID: 39809768	2025
Control of virulence and physiology by the flagellin homeostasis checkpoint FliC-FliW-CsrA in the absence of motility. mBio\| PubMed ID: 39882902	2025
Emerging ribotypes have divergent metabolic phenotypes. mSystems\| PubMed ID: 40013784	2025
Limosilactobacillus reuteri promotes the expression and secretion of enteroendocrine- and enterocyte-derived hormones. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 40098558	2025
A thiouracil desulfurase protects Clostridioides difficile RNA from 4-thiouracil incorporation, providing a competitive advantage in the gut. Cell host & microbe\| PubMed ID: 40139192	2025
Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 40323169	2025
Present and future of microbiome-targeting therapeutics. The Journal of clinical investigation\| PubMed ID: 40454480	2025
Increased fungal burden in the gastrointestinal tract of brain-dead organ donors. Microbiology spectrum\| PubMed ID: 40530808	2025
Limosilactobacillus reuteri enables oral-to-systemic absorption of iberiotoxin for treatment of collagen-induced arthritis in rats. Microbial cell factories\| PubMed ID: 40753423	2025