3d-cine-magnetic-resonance-imaging-respiratory-motion-mechanically

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

The pathophysiology of diaphragm dysfunction in mechanically ventilated patients has yet to be fully understood, and adequate animal models are required ...

Amsterdam University Medical Center

Loss of muscle mass and strength is provoked by critical illness. Our primary aim was to study the development of muscle atrophy and weakness in vitro in isolated myofibers and in vivo muscle mass and in vitro muscle strength during the first week of critical illness. Furthermore, we explored how in vitro muscle strength compares to healthy controls. Finally, we studied correlations between in vitro muscle mass and strength and in vivo muscle mass in critically ill patients.

Wout Claassen

Biography

JoVE Journal Publications

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