Leo Heunks

Department of Intensive Care, Radboud university medical center

Affiliated withRadboud university medical center

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
Noninvasive ventilation and the upper airway: should we pay more attention? Critical care (London, England)\| PubMed ID: 24314000	2013
Automated patient-ventilator interaction analysis during neurally adjusted non-invasive ventilation and pressure support ventilation in chronic obstructive pulmonary disease. Critical care (London, England)\| PubMed ID: 25307894	2014
Levosimendan affects oxidative and inflammatory pathways in the diaphragm of ventilated endotoxemic mice. Critical care (London, England)\| PubMed ID: 25888356	2015
Assisted Ventilation in Patients with Acute Respiratory Distress Syndrome: Lung-distending Pressure and Patient-Ventilator Interaction. Anesthesiology\| PubMed ID: 25955983	2015
EFFECTS OF EXPERIMENTAL HUMAN ENDOTOXEMIA ON DIAPHRAGM FUNCTION. Shock (Augusta, Ga.)\| PubMed ID: 26196838	2015
Comparison Between Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation Levels in Terms of Respiratory Effort. Critical care medicine\| PubMed ID: 26540399	2016
Strategies to optimize respiratory muscle function in ICU patients. Critical care (London, England)\| PubMed ID: 27091359	2016
Assessment of dead-space ventilation in patients with acute respiratory distress syndrome: a prospective observational study. Critical care (London, England)\| PubMed ID: 27145818	2016
Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper. International journal of cardiology\| PubMed ID: 27498374	2016
Partial Neuromuscular Blockade during Partial Ventilatory Support in Sedated Patients with High Tidal Volumes. American journal of respiratory and critical care medicine\| PubMed ID: 27748627	2017
Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study. Intensive care medicine\| PubMed ID: 27757516	2016
Functional assessment of the diaphragm by speckle tracking ultrasound during inspiratory loading. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 28522757	2017
Diaphragm Atrophy and Weakness in the Absence of Mitochondrial Dysfunction in the Critically Ill. American journal of respiratory and critical care medicine\| PubMed ID: 28787181	2017
Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study. Intensive care medicine\| PubMed ID: 29138899	2018
Respiratory Muscle Effort during Expiration in Successful and Failed Weaning from Mechanical Ventilation. Anesthesiology\| PubMed ID: 29771711	2018
Acetylcholine receptor antagonists in acute respiratory distress syndrome: much more than muscle relaxants. Critical care (London, England)\| PubMed ID: 29788993	2018
Glottic patency during noninvasive ventilation in patients with chronic obstructive pulmonary disease. Respiratory physiology & neurobiology\| PubMed ID: 30026086	2019
Estimation of the diaphragm neuromuscular efficiency index in mechanically ventilated critically ill patients. Critical care (London, England)\| PubMed ID: 30261920	2018
Monitoring patient-ventilator breath contribution in the critically ill during neurally adjusted ventilatory assist: reliability and improved algorithms for bedside use. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 31161879	2019
Expiratory muscle dysfunction in critically ill patients: towards improved understanding. Intensive care medicine\| PubMed ID: 31236639	2019
Effects of levosimendan on respiratory muscle function in patients weaning from mechanical ventilation. Intensive care medicine\| PubMed ID: 31576436	2019
Patient-Ventilator Interaction During Noninvasive Ventilation in Subjects With Exacerbation of COPD: Effect of Support Level and Ventilator Mode. Respiratory care\| PubMed ID: 32156788	2020
Ventilating two patients with one ventilator: technical setup and laboratory testing. ERJ open research\| PubMed ID: 32665947	2020
The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children. Annals of intensive care\| PubMed ID: 32852710	2020
Breath-synchronized electrical stimulation of the expiratory muscles in mechanically ventilated patients: a randomized controlled feasibility study and pooled analysis. Critical care (London, England)\| PubMed ID: 33126902	2020
Diaphragm Atrophy as a Risk Factor for Extubation Failure. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies\| PubMed ID: 34192735	2021
Positive end-expiratory pressure affects geometry and function of the human diaphragm. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 34473571	2021
Early Restrictive Fluid Strategy Impairs the Diaphragm Force in Lambs with Acute Respiratory Distress Syndrome. Anesthesiology\| PubMed ID: 35320344	2022
INCIDENCE, RISK FACTORS, AND OUTCOME OF SUSPECTED CENTRAL VENOUS CATHETER-RELATED INFECTIONS IN CRITICALLY ILL COVID-19 PATIENTS: A MULTICENTER RETROSPECTIVE COHORT STUDY. Shock (Augusta, Ga.)\| PubMed ID: 36155964	2022
Incidence, risk factors and pre-emptive screening for COVID-19 associated pulmonary aspergillosis in an era of immunomodulant therapy. Journal of critical care\| PubMed ID: 36801598	2023
Reference values of diaphragmatic dimensions in healthy children aged 0-8 years. European journal of pediatrics\| PubMed ID: 36939879	2023
No association between thickening fraction of the diaphragm and extubation success in ventilated children. Frontiers in pediatrics\| PubMed ID: 37033174	2023
The diagnostic accuracy of lung ultrasound to determine PiCCO-derived extravascular lung water in invasively ventilated patients with COVID-19 ARDS. The ultrasound journal\| PubMed ID: 37782370	2023
Effects of early versus delayed application of prone position on ventilation-perfusion mismatch in patients with acute respiratory distress syndrome: a prospective observational study. Critical care (London, England)\| PubMed ID: 38012731	2023
Setting positive end-expiratory pressure: role in diaphragm-protective ventilation. Current opinion in critical care\| PubMed ID: 38085880	2024
Diaphragm Activity during Expiration in Ventilated Critically Ill Patients. American journal of respiratory and critical care medicine\| PubMed ID: 38190708	2024
Critical Care: A Special Issue of the Blue Journal. American journal of respiratory and critical care medicine\| PubMed ID: 38300147	2024
Reply to Akoumianaki : Studying Diaphragm Activity during Expiration in Mechanically Ventilated Patients: Expiratory Asynchrony Is Important. American journal of respiratory and critical care medicine\| PubMed ID: 38457815	2024
Critical Care: A Second Special Issue of the Blue Journal. American journal of respiratory and critical care medicine\| PubMed ID: 38501798	2024
The Value of Ischemic Cardiac Biomarkers to Predict Spontaneous Breathing Trial or Extubation Failure: A Systematic Review. Journal of clinical medicine\| PubMed ID: 38892952	2024
Clinical implementation of advanced respiratory monitoring with esophageal pressure and electrical impedance tomography: results from an international survey and focus group discussion. Intensive care medicine experimental\| PubMed ID: 39432136	2024
How I perform diaphragmatic ultrasound in the intensive care unit. Intensive care medicine\| PubMed ID: 39470799	2024
Advances in achieving lung and diaphragm-protective ventilation. Current opinion in critical care\| PubMed ID: 39560149	2025
A signal model for fat-suppressed T-mapping and dynamic contrast-enhanced MRI with interrupted spoiled gradient-echo readout. NMR in biomedicine\| PubMed ID: 39571186	2025
Diaphragm Pacing in Early Critical Illness? A Plea for a Super-Relaxed Approach. American journal of respiratory and critical care medicine\| PubMed ID: 39701028	2025
Overcoming left diaphragm ultrasound challenges: exploring promising techniques. Intensive care medicine\| PubMed ID: 39714618	2025
Blowing in the Wind: The Uncertain Impact of Inspiratory Muscle Strength Training in ICU Patients. American journal of respiratory and critical care medicine\| PubMed ID: 39773199	2025
How we use ultrasound in the management of weaning from mechanical ventilation. Intensive care medicine\| PubMed ID: 39774857	2025
The prognostic role of cardiac and inflammatory biomarkers in extubation failure in patients with COVID-19 acute respiratory distress syndrome. Annals of intensive care\| PubMed ID: 39779607	2025
Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study. Annals of intensive care\| PubMed ID: 39828725	2025
Early versus Delayed Switching from Controlled to Assisted Ventilation: A Target Trial Emulation. American journal of respiratory and critical care medicine\| PubMed ID: 39836177	2025
Solid-state esophageal pressure sensor for the estimation of pleural pressure: a bench and first-in-human validation study. Critical care (London, England)\| PubMed ID: 39871347	2025
High-flow nasal oxygen vs. conventional oxygen therapy in patients with COVID-19 related acute hypoxemic respiratory failure and a do not intubate order: a multicentre cohort study. Respiratory research\| PubMed ID: 40281556	2025
Correction: Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study. Annals of intensive care\| PubMed ID: 40293560	2025
Flow Index as a Noninvasive Method to Evaluate Inspiratory Effort in Patients on Pressure Support Ventilation. Respiratory care\| PubMed ID: 40397651	2025
Effect of initiation of invasive ventilation in acute hypoxemic respiratory failure using sequential trials: treatment efficacy instead of timing. Critical care (London, England)\| PubMed ID: 40462175	2025
The effect of mechanical ventilation on respiratory muscle echogenicity in critically ill children: an observational cohort study. BMC pediatrics\| PubMed ID: 40604629	2025
Diaphragm Neurostimulation: An Innovative Approach to Treat Diaphragm Weakness in Difficult to Wean Patients? American journal of respiratory and critical care medicine\| PubMed ID: 40720862	2025
Assessing inspiratory drive and effort in critically ill patients at the bedside. Critical care (London, England)\| PubMed ID: 40745324	2025