Chunxiang Zhang

Basic Medicine Research Innovation Center for Cardiometabolic Diseases, southwest medical university

Affiliated withsouthwest medical university

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Insulin resistance plays a potential role in postoperative cognitive dysfunction in patients following cardiac valve surgery. Brain research\| PubMed ID: 28048971	2017
Abnormal Expression of MicroRNAs Induced by Chronic Unpredictable Mild Stress in Rat Hippocampal Tissues. Molecular neurobiology\| PubMed ID: 28083819	2018
MiR-146a protects small intestine against ischemia/reperfusion injury by down-regulating TLR4/TRAF6/NF-κB pathway. Journal of cellular physiology\| PubMed ID: 28771774	2018
Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats. Experimental & molecular medicine\| PubMed ID: 30369596	2018
Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia/Reperfusion. Oxidative medicine and cellular longevity\| PubMed ID: 31191804	2019
Serum miR-221-3p as a new potential biomarker for depressed mood in perioperative patients. Brain research\| PubMed ID: 31211948	2019
Abnormal expression of rno_circRNA_014900 and rno_circRNA_005442 induced by ketamine in the rat hippocampus. BMC psychiatry\| PubMed ID: 31898506	2020
Pharmacological and cardiovascular perspectives on the treatment of COVID-19 with chloroquine derivatives. Acta pharmacologica Sinica\| PubMed ID: 32968208	2020
The effect of miR-471-3p on macrophage polarization in the development of diabetic cardiomyopathy. Life sciences\| PubMed ID: 33417962	2021
IL-1β in atherosclerotic vascular calcification: From bench to bedside. International journal of biological sciences\| PubMed ID: 34803503	2021
Nanoparticle-based delivery systems modulate the tumor microenvironment in pancreatic cancer for enhanced therapy. Journal of nanobiotechnology\| PubMed ID: 34809634	2021
Cardiovascular Complications of COVID-19 Vaccines. Frontiers in cardiovascular medicine\| PubMed ID: 35369340	2022
Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy. Circulation\| PubMed ID: 35400201	2022
Large-Scale Profiling on lncRNAs in Human Platelets: Correlation with Platelet Reactivity. Cells\| PubMed ID: 35883699	2022
Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome. Endocrine\| PubMed ID: 36068422	2022
ATIC-Associated De Novo Purine Synthesis Is Critically Involved in Proliferative Arterial Disease. Circulation\| PubMed ID: 36073366	2022
A comprehensive review of L.: Traditional uses, phytochemistry, pharmacological activities, and clinical applications. Frontiers in pharmacology\| PubMed ID: 36160419	2022
MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway. Stroke and vascular neurology\| PubMed ID: 36241224	2023
LncRNAs in blood cells: Roles in cell development and potential pathogenesis in hematological malignancies. Critical reviews in oncology/hematology\| PubMed ID: 36261116	2022
Correction: Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats. Experimental & molecular medicine\| PubMed ID: 36443566	2022
Taxillus chinensis (DC.) Danser: a comprehensive review on botany, traditional uses, phytochemistry, pharmacology, and toxicology. Chinese medicine\| PubMed ID: 36482376	2022
LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis. Life sciences\| PubMed ID: 36496032	2023
Targeting a thrombopoietin-independent strategy in the discovery of a novel inducer of megakaryocytopoiesis, DMAG, for the treatment of thrombocytopenia. Haematologica\| PubMed ID: 36546424	2023
Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment. Journal of nanobiotechnology\| PubMed ID: 36575429	2022
Novel chemical-structure TPOR agonist, TMEA, promotes megakaryocytes differentiation and thrombopoiesis via mTOR and ERK signalings. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 36610353	2023
Apoptosis in megakaryocytes: Safeguard and threat for thrombopoiesis. Frontiers in immunology\| PubMed ID: 36685543	2022
Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models. European heart journal\| PubMed ID: 36721994	2023
The mechanism of rh-endostatin-induced cardiotoxicity and its protection by dihydromyricetin[in vivo/in vitro, C57BL/6 mice, AC16 and hiPSC-CMs]. Toxicology letters\| PubMed ID: 36739041	2023
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome. Clinical science (London, England : 1979)\| PubMed ID: 36752638	2023
High Glucose-Induced Kidney Injury via Activation of Necroptosis in Diabetic Kidney Disease. Oxidative medicine and cellular longevity\| PubMed ID: 36756299	2023
The Application of Ethnomedicine in Modulating Megakaryocyte Differentiation and Platelet Counts. International journal of molecular sciences\| PubMed ID: 36834579	2023
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes. Signal transduction and targeted therapy\| PubMed ID: 36882410	2023
Recent progress in therapeutic strategies and biomimetic nanomedicines based on neutrophils for inflammation treatment. Nanomedicine (London, England)\| PubMed ID: 37165973	2023
Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair. Bioengineering & translational medicine\| PubMed ID: 37206208	2023
Hypoxia-responsive lncRNA G077640 promotes ESCC tumorigenesis via the H2AX-HIF1α-glycolysis axis. Carcinogenesis\| PubMed ID: 37248865	2023
Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome. Journal of ovarian research\| PubMed ID: 37393270	2023
The effects and mechanism of LncRNA NORAD on doxorubicin-induced cardiotoxicity. Toxicology\| PubMed ID: 37406984	2023
Corrigendum to 'The effect of miR-471-3p on macrophage polarization in the development of diabetic cardiomyopathy' [Life Sciences 268 (2021) 118989]. Life sciences\| PubMed ID: 37423776	2023
Leukocyte-Specific Morrbid Promotes Leukocyte Differentiation and Atherogenesis. Research (Washington, D.C.)\| PubMed ID: 37426471	2023
Stress-enhanced cardiac lncRNA Morrbid protects hearts from acute myocardial infarction. JCI insight\| PubMed ID: 37432746	2023
Understanding sorafenib-induced ferroptosis and resistance mechanisms: Implications for cancer therapy. European journal of pharmacology\| PubMed ID: 37460053	2023
Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction. Cell communication and signaling : CCS\| PubMed ID: 37580705	2023
Different stimuli induce endothelial dysfunction and promote atherosclerosis through the Piezo1/YAP signaling axis. Archives of biochemistry and biophysics\| PubMed ID: 37714252	2023
Exploring the role of esketamine in alleviating depressive symptoms in mice via the PGC-1α/irisin/ERK1/2 signaling pathway. Scientific reports\| PubMed ID: 37789092	2023
L-type calcium ion channel-mediated activation of autophagy in vascular smooth muscle cells via thonningianin A (TA) alleviates vascular calcification in type 2 diabetes mellitus. European journal of pharmacology\| PubMed ID: 37806540	2023
BDH1-mediated βOHB metabolism ameliorates diabetic kidney disease by activation of NRF2-mediated antioxidative pathway. Aging\| PubMed ID: 38015723	2023
Nano-modulators with the function of disrupting mitochondrial Ca homeostasis and photothermal conversion for synergistic breast cancer therapy. Journal of nanobiotechnology\| PubMed ID: 38049882	2023
Corrigendum to "Different stimuli induce endothelial dysfunction and promote atherosclerosis through the Piezo1/YAP signaling axis" [Arch. Biochem. Biophys. 747 (1 October 2023) 109755]. Archives of biochemistry and biophysics\| PubMed ID: 38142171	2024
Macrophage CREBZF Orchestrates Inflammatory Response to Potentiate Insulin Resistance and Type 2 Diabetes. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 38286660	2024
Generation of human vascularized and chambered cardiac organoids for cardiac disease modelling and drug evaluation. Cell proliferation\| PubMed ID: 38453465	2024
Deletion of in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice. Genes & diseases\| PubMed ID: 38515941	2024
Corrigendum to "Different stimuli induce endothelial dysfunction and promote atherosclerosis through the Piezo1/YAP signaling axis" [Arch. Biochem. Biophys. 747 (1 October 2023) 109755]. Archives of biochemistry and biophysics\| PubMed ID: 38777671	2024
The effect of macrophages and their exosomes in ischemic heart disease. Frontiers in immunology\| PubMed ID: 38799471	2024
The ischemia-enhanced myocardial infarction protection-related lncRNA protects against acute myocardial infarction. MedComm\| PubMed ID: 38988491	2024
Aging aggravates aortic aneurysm and dissection via miR-1204-MYLK signaling axis in mice. Nature communications\| PubMed ID: 39013850	2024
Disruption of cyclin D1 degradation leads to the development of mantle cell lymphoma. Acta pharmaceutica Sinica. B\| PubMed ID: 39027231	2024
CircKat6b Mediates the Antidepressant Effect of Esketamine by Regulating Astrocyte Function. Molecular neurobiology\| PubMed ID: 39138759	2025
Gut microbiota-derived indole-3-propionic acid alleviates diabetic kidney disease through its mitochondrial protective effect via reducing ubiquitination mediated-degradation of SIRT1. Journal of advanced research\| PubMed ID: 39147198	2025
Hormonal influence: unraveling the impact of sex hormones on vascular smooth muscle cells. Biological research\| PubMed ID: 39227995	2024
Tetraspanins in digestive‑system cancers: Expression, function and therapeutic potential (Review). Molecular medicine reports\| PubMed ID: 39239742	2024
Current insights and future directions of LncRNA Morrbid in disease pathogenesis. Heliyon\| PubMed ID: 39263145	2024
Glucose metabolite methylglyoxal induces vascular endothelial cell pyroptosis via NLRP3 inflammasome activation and oxidative stress in vitro and in vivo. Cellular and molecular life sciences : CMLS\| PubMed ID: 39269632	2024
The role of nonmyocardial cells in the development of diabetic cardiomyopathy and the protective effects of FGF21: a current understanding. Cell communication and signaling : CCS\| PubMed ID: 39327594	2024
Glucagon-like peptide-1 receptor agonists: Exploring the mechanisms from glycemic control to treatment of multisystemic diseases. World journal of gastroenterology\| PubMed ID: 39351253	2024
Advances in the research of intestinal fungi in Crohn's disease. World journal of gastroenterology\| PubMed ID: 39492826	2024
Exploring heat shock proteins as therapeutic targets for Parkinson's disease. Biochemical pharmacology\| PubMed ID: 39551273	2024
From biomarker discovery to combined therapies: Advancing hepatocellular carcinoma treatment strategies. World journal of gastrointestinal oncology\| PubMed ID: 39554736	2024
Sexually dimorphic dopaminergic circuits determine sex preference. Science (New York, N.Y.)\| PubMed ID: 39787240	2025
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway. In vitro cellular & developmental biology. Animal\| PubMed ID: 39806237	2025
Advances in cardiac organoid research: implications for cardiovascular disease treatment. Cardiovascular diabetology\| PubMed ID: 39827092	2025
Sepsis-induced cardiac dysfunction: mitochondria and energy metabolism. Intensive care medicine experimental\| PubMed ID: 39966268	2025
BDH1 overexpression alleviates diabetic cardiomyopathy through inhibiting H3K9bhb-mediated transcriptional activation of LCN2. Cardiovascular diabetology\| PubMed ID: 40022118	2025
Multimodal discovery of bavachinin A: A natural FLT3 agonist for treating thrombocytopenia. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 40058315	2025
P21-Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 40068092	2025
Associations between air pollution and hospitalization for cardiovascular disease: a time series study in Nanchong. Frontiers in public health\| PubMed ID: 40124414	2025
Hypothalamic GABAergic neurons: their roles in health and metabolic diseases. Frontiers in endocrinology\| PubMed ID: 40130157	2025
Clonal hematopoiesis of indeterminate potential: contribution to disease and promising interventions. Molecular and cellular biochemistry\| PubMed ID: 40140229	2025
Roles of Autophagy, Mitophagy, and Mitochondria in Left Ventricular Remodeling after Myocardial Infarction. Reviews in cardiovascular medicine\| PubMed ID: 40160572	2025
Cardiovascular diseases and depression: A meta-analysis and Mendelian randomization analysis. Molecular psychiatry\| PubMed ID: 40247128	2025
Correction to: Clonal hematopoiesis of indeterminate potential: contribution to disease and promising interventions. Molecular and cellular biochemistry\| PubMed ID: 40314848	2025
Life-Saving Drug or Potential Threat? The Role of Mineralocorticoid Receptor Antagonists in Myocardial Infarction: A Meta-Analysis. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists\| PubMed ID: 40345581	2025
Correction: Cardiovascular diseases and depression: A meta-analysis and Mendelian randomization analysis. Molecular psychiatry\| PubMed ID: 40369232	2025
Thyroid hormone ameliorates ursodeoxycholic acid-induced heart damage in zebrafish embryos. Life sciences\| PubMed ID: 40389024	2025
Understanding the Mechanism of Cardiotoxicity Induced by Nanomaterials: A Comprehensive Review. Small science\| PubMed ID: 40395348	2025
Targeting mitochondrial ClpP: structural insights and therapeutic potential of ClpP agonists in cancer therapy. Oncology reviews\| PubMed ID: 40395852	2025
Progranulin's Protective Mechanisms and Therapeutic Potential in Cardiovascular Disease. Cells\| PubMed ID: 40497937	2025
4-Octyl itaconate alleviates endothelial cell inflammation and barrier dysfunction in LPS-induced sepsis via modulating TLR4/MAPK/NF-κB signaling : 4-Octyl itaconate alleviates endothelial d... Molecular medicine (Cambridge, Mass.)\| PubMed ID: 40524158	2025
Small Nucleolar RNAs: Biological Functions and Diseases. MedComm\| PubMed ID: 40584410	2025
PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth. Cell reports\| PubMed ID: 40742808	2025
Transcripts of splicing factors with time-varying associations with survival outcomes in colorectal cancer. American journal of cancer research\| PubMed ID: 40814364	2025
Advances in fibroblast-based cardiac reprogramming in the treatment of heart disease. Inflammation research : official journal of the European Histamine Research Society ... [et al.]\| PubMed ID: 40853551	2025
G3BP1 maintains endothelial barrier integrity through dual mechanisms: direct stabilization of junction protein mRNAs and suppression of the inflammatory MYD88-ARNO-ARF6 pathway. Angiogenesis\| PubMed ID: 40855241	2025
The X-Age Project to construct a Chinese aging clock. Nature aging\| PubMed ID: 40926127	2025
The role of tetraspanins in organ fibrosis: mechanisms and therapeutic perspectives. Journal of translational medicine\| PubMed ID: 40993816	2025
Therapeutic potential of human umbilical cord mesenchymal stem cell-derived exosomes in myocardial infarction: from molecular mechanisms to clinical translation-an update. Frontiers in pharmacology\| PubMed ID: 41001344	2025
Empagliflozin Preserves Cardiomyocyte Structural Homeostasis via the Stabilization of the Integrin α5-Desmocollin-2 Adhesion Axis in Sepsis-Induced Cardiomyopathy. Cells\| PubMed ID: 41002417	2025
TSPAN4 controls vascular smooth muscle cell phenotypic switching and intimal hyperplasia by targeting TPM1-regulated cytoskeletal organization. Clinical science (London, England : 1979)\| PubMed ID: 41004162	2025