Jared K. Burks

Department of Leukemia, The University of Texas MD Anderson Cancer Center

Affiliated withThe University of Texas MD Anderson Cancer Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 5	Year
Publication title Cited by 1	2025
Publication title	2025
Publication title	2025
Publication title	2025
Publication title	2025

Other Publications

Article	Year
Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only pr... Cancer research\| PubMed ID: 20215498	2010
Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 20664358	2010
Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells. Journal of cellular biochemistry\| PubMed ID: 21360576	2011
Prognostic impact and targeting of CRM1 in acute myeloid leukemia. Blood\| PubMed ID: 23564911	2013
The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells. Biochimica et biophysica acta\| PubMed ID: 24858343	2014
Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 25598437	2015
Stromal Cells Derived from Visceral and Obese Adipose Tissue Promote Growth of Ovarian Cancers. PloS one\| PubMed ID: 26317219	2015
PD-L1 expression and prognostic impact in glioblastoma. Neuro-oncology\| PubMed ID: 26323609	2016
Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells. Biochimica et biophysica acta\| PubMed ID: 26704388	2016
Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network. Oncotarget\| PubMed ID: 26956049	2016
Integrated genomic analysis of recurrence-associated small non-coding RNAs in oesophageal cancer. Gut\| PubMed ID: 27507904	2017
Prognostic Factors for Locoregional Recurrence in Patients with Thoracic Esophageal Squamous Cell Carcinoma Treated with Radical Two-Field Lymph Node Dissection: Results from Long-Term Follo... Annals of surgical oncology\| PubMed ID: 27804027	2017
Rapid monoisotopic cisplatin based barcoding for multiplexed mass cytometry. Scientific reports\| PubMed ID: 28630464	2017
Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in -Mutant Acute Myeloid Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 29463558	2018
Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes. Oncoimmunology\| PubMed ID: 29632728	2018
Mammary stem cell and macrophage markers are enriched in normal tissue adjacent to inflammatory breast cancer. Breast cancer research and treatment\| PubMed ID: 29858753	2018
An ARC-Regulated IL1β/Cox-2/PGE2/β-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML. Cancer research\| PubMed ID: 30674535	2019
Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape. Oncoimmunology\| PubMed ID: 30906661	2019
Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models. Haematologica\| PubMed ID: 31123034	2020
Antileukemia Effects of Notch-Mediated Inhibition of Oncogenic PLK1 in B-Cell Acute Lymphoblastic Leukemia. Molecular cancer therapeutics\| PubMed ID: 31227645	2019
Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes. Cell\| PubMed ID: 31398337	2019
Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma. Investigative ophthalmology & visual science\| PubMed ID: 31596927	2019
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma. Haematologica\| PubMed ID: 32029507	2021
Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer. Cell reports\| PubMed ID: 32294438	2020
Radiation with STAT3 Blockade Triggers Dendritic Cell-T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 32605912	2020
The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling. Gastroenterology\| PubMed ID: 32805281	2020
SIO: A Spatioimageomics Pipeline to Identify Prognostic Biomarkers Associated with the Ovarian Tumor Microenvironment. Cancers\| PubMed ID: 33917869	2021
The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells. Cancer research\| PubMed ID: 34003775	2021
Extended live-cell barcoding approach for multiplexed mass cytometry. Scientific reports\| PubMed ID: 34117319	2021
Immune microenvironment composition in high-grade serous ovarian cancers based on BRCA mutational status. Journal of cancer research and clinical oncology\| PubMed ID: 34476576	2021
Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and ... Redox biology\| PubMed ID: 34619528	2021
Cytometry of Mass for Murine Immunoprofiling. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34993943	2022
Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma. Cell death & disease\| PubMed ID: 35121729	2022
ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma. Nature cancer\| PubMed ID: 35121903	2021
Publisher Correction: ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma. Nature cancer\| PubMed ID: 35149861	2022
Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression. JCI insight\| PubMed ID: 35316217	2022
Correction: Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma. Cell death & disease\| PubMed ID: 35501311	2022
Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer cell\| PubMed ID: 35537412	2022
CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2. Cancer research\| PubMed ID: 35771632	2022
Distinct immune signature predicts progression of vestibular schwannoma and unveils a possible viral etiology. Journal of experimental & clinical cancer research : CR\| PubMed ID: 36195959	2022
3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma. The Journal of clinical investigation\| PubMed ID: 36282600	2022
Radiation therapy induces immunosenescence mediated by p90RSK. Frontiers in cardiovascular medicine\| PubMed ID: 36426217	2022
EGFR is a master switch between immunosuppressive and immunoactive tumor microenvironment in inflammatory breast cancer. Science advances\| PubMed ID: 36525493	2022
Spatial Transcriptomics Depict Ligand-Receptor Cross-talk Heterogeneity at the Tumor-Stroma Interface in Long-Term Ovarian Cancer Survivors. Cancer research\| PubMed ID: 36787106	2023
Mdm2/p53 levels in bone marrow mesenchymal stromal cells is essential for maintaining the hematopoietic niche in response to DNA damage. Research square\| PubMed ID: 36909480	2023
FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML. Leukemia\| PubMed ID: 37085610	2023
Single-Cell Profiling of CD8+ T Cells in Acute Myeloid Leukemia Reveals a Continuous Spectrum of Differentiation and Clonal Hyperexpansion. Cancer immunology research\| PubMed ID: 37163233	2023
An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis. Circulation research\| PubMed ID: 37264926	2023
Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential. Cancer discovery\| PubMed ID: 37285225	2023
Mdm2/p53 levels in bone marrow mesenchymal stromal cells are essential for maintaining the hematopoietic niche in response to DNA damage. Cell death & disease\| PubMed ID: 37353528	2023
Inflammation induced by tumor-associated nerves promotes resistance to anti-PD-1 therapy in cancer patients and is targetable by interleukin-6 blockade. Research square\| PubMed ID: 37503252	2023
Inhibition of Microsomal Prostaglandin E2 Synthase Reduces Collagen Deposition in Melanoma Tumors and May Improve Immunotherapy Efficacy by Reducing T-cell Exhaustion. Cancer research communications\| PubMed ID: 37529399	2023
Cytosolic DNA accumulation promotes breast cancer immunogenicity via a STING-independent pathway. Journal for immunotherapy of cancer\| PubMed ID: 37907220	2023
Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response. Nature communications\| PubMed ID: 38167338	2024
Increased expression of CD70 in relapsed acute myeloid leukemia after hypomethylating agents. Virchows Archiv : an international journal of pathology\| PubMed ID: 38388965	2024
Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies. Nature communications\| PubMed ID: 38418901	2024
Molecular, Metabolic, and Subcellular Mapping of the Tumor Immune Microenvironment via 3D Targeted and Non-Targeted Multiplex Multi-Omics Analyses. Cancers\| PubMed ID: 38473208	2024
Antiangiogenic Tyrosine Kinase Inhibitors have Differential Efficacy in Clear Cell Renal Cell Carcinoma in Bone. Cancer research communications\| PubMed ID: 39248577	2024
Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 39817327	2025
High Dimensional Proteomic Multiplex Imaging of the Central Nervous System Using the COMET System. bioRxiv : the preprint server for biology\| PubMed ID: 40027731	2025
Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics. Cancer cell\| PubMed ID: 40154487	2025
Sickle cell disease induces chromatin introversion and ferroptosis in CD8 T cells to suppress anti-tumor immunity. Immunity\| PubMed ID: 40359940	2025
Multimodal spatial proteomic profiling in acute myeloid leukemia. NPJ precision oncology\| PubMed ID: 40394148	2025
Selective Alanine Transporter Utilization Is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer. Cancer research\| PubMed ID: 40658600	2025
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy. Nature\| PubMed ID: 40836096	2025