Barry E. Kennedy

Department of Pathology, Dalhousie University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein. Journal of lipid research\| PubMed ID: 19965586	2010
Niemann-Pick Type C2 protein contributes to the transport of endosomal cholesterol to mitochondria without interacting with NPC1. Journal of lipid research\| PubMed ID: 22962690	2012
Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain. PloS one\| PubMed ID: 24367541	2013
Adaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells. The Journal of biological chemistry\| PubMed ID: 24790103	2014
Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function. Journal of bioenergetics and biomembranes\| PubMed ID: 25425472	2016
Presymptomatic Alterations in Amino Acid Metabolism and DNA Methylation in the Cerebellum of a Murine Model of Niemann-Pick Type C Disease. The American journal of pathology\| PubMed ID: 27083515	2016
NAD salvage pathway in cancer metabolism and therapy. Pharmacological research\| PubMed ID: 27816507	2016
Autophagic homeostasis is required for the pluripotency of cancer stem cells. Autophagy\| PubMed ID: 27929731	2017
Measurement of Mitochondrial Cholesterol Import Using a Mitochondria-Targeted CYP11A1 Fusion Construct. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28205173	2017
Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages. Journal of proteome research\| PubMed ID: 28768414	2017
Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis. Acta neuropathologica communications\| PubMed ID: 29301568	2018
Regulation of Cancer and Cancer-Related Genes via NAD. Antioxidants & redox signaling\| PubMed ID: 29334761	2019
TRPM2 channel-mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway. The Journal of biological chemistry\| PubMed ID: 29343514	2018
RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 30078441	2018
The NAD Salvage Pathway Supports PHGDH-Driven Serine Biosynthesis. Cell reports\| PubMed ID: 30157431	2018
TAp73 Modifies Metabolism and Positively Regulates Growth of Cancer Stem-Like Cells in a Redox-Sensitive Manner. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 30593514	2019
Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus. Cancer research\| PubMed ID: 31088833	2019
Quantitative Proteome Responses to Oncolytic Reovirus in GM-CSF- and M-CSF-Differentiated Bone Marrow-Derived Cells. Journal of proteome research\| PubMed ID: 31884793	2020
Targeting NAD Synthesis to Potentiate CD38-Based Immunotherapy of Multiple Myeloma. Trends in cancer\| PubMed ID: 31952784	2020
Targeted Metabolic Reprogramming to Improve the Efficacy of Oncolytic Virus Therapy. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 32243836	2020
Neuronal mitochondrial calcium uniporter deficiency exacerbates axonal injury and suppresses remyelination in mice subjected to experimental autoimmune encephalomyelitis. Experimental neurology\| PubMed ID: 32745471	2020
DMG26: A Targeted Sequencing Panel for Mutation Profiling to Address Gaps in the Prognostication of Multiple Myeloma. The Journal of molecular diagnostics : JMD\| PubMed ID: 34562616	2021
NAD+ depletion enhances reovirus-induced oncolysis in multiple myeloma. Molecular therapy oncolytics\| PubMed ID: 35284625	2022
After virus exposure, early bystander naïve CD8 T cell activation relies on NAD salvage metabolism. Frontiers in immunology\| PubMed ID: 36818473	2022
Recent Advances in Phytochemical-Based Topical Applications for the Management of Eczema: A Review. International journal of molecular sciences\| PubMed ID: 38791412	2024
Targeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically 'cold' tumor models. Frontiers in immunology\| PubMed ID: 39872527	2024
Advancing Medical Applications of Cancer Nanotechnology: Highlighting Two Decades of the NCI'S Nanotechnology Characterization Laboratory Service to the Research Community. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology\| PubMed ID: 40458962	2025