Cheryl Dean

Department of Pathology, Dalhousie University

Affiliated withDalhousie University

Research Area

Cancer Research

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Oncolytic reovirus effectively targets breast cancer stem cells. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19293772	2009
Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis. Stem cells (Dayton, Ohio)\| PubMed ID: 21280157	2011
Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21552008	2011
Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling. Molecular oncology\| PubMed ID: 25106087	2015
Core needle biopsy of breast cancer tumors increases distant metastases in a mouse model. Neoplasia (New York, N.Y.)\| PubMed ID: 25425969	2014
Newly recruited CD11b+, GR-1+, Ly6C(high) myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25825443	2015
Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1. Oncotarget\| PubMed ID: 27286452	2016
Epigenetic Silencing of TAP1 in Aldefluor Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion. Stem cells (Dayton, Ohio)\| PubMed ID: 29341428	2018
DNA Methylation Predicts the Response of Triple-Negative Breast Cancers to All-Trans Retinoic Acid. Cancers\| PubMed ID: 30352973	2018
ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells. Cell death and differentiation\| PubMed ID: 31197235	2020
Retinoic acid and arsenic trioxide induce lasting differentiation and demethylation of target genes in APL cells. Scientific reports\| PubMed ID: 31263158	2019
Decitabine Response in Breast Cancer Requires Efficient Drug Processing and Is Not Limited by Multidrug Resistance. Molecular cancer therapeutics\| PubMed ID: 32156786	2020
Human-specific GAPDH qRT-PCR is an accurate and sensitive method of xenograft metastasis quantification. Molecular therapy. Methods & clinical development\| PubMed ID: 33575432	2021
LncRNA Promotes Proliferation and Migration, Is Associated with Cancer Stem Cells, and Alters the miRNA Landscape in Triple-Negative Breast Cancer. Cancers\| PubMed ID: 34072264	2021
Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 34989902	2022
LncRNAs exhibit subtype-specific expression, survival associations, and cancer-promoting effects in breast cancer. Gene\| PubMed ID: 38219875	2024
ALDH1A3 is the switch that determines the balance of ALDH and CD24CD44 cancer stem cells, EMT-MET, and glucose metabolism in breast cancer. Oncogene\| PubMed ID: 39251846	2024
Targeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically 'cold' tumor models. Frontiers in immunology\| PubMed ID: 39872527	2024
Advancing Medical Applications of Cancer Nanotechnology: Highlighting Two Decades of the NCI'S Nanotechnology Characterization Laboratory Service to the Research Community. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology\| PubMed ID: 40458962	2025