Weihua Li

Department of Pathology, Chinese Academy of Medical Sciences and Peking Union Medical College

Affiliated withChinese Academy of Medical Sciences and Peking Union Medical College

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Major challenges related to tumor biological characteristics in accurate mutation detection of colorectal cancer by next-generation sequencing. Cancer letters\| PubMed ID: 28942013	2017
Distinct MET Protein Localization Associated With MET Exon 14 Mutation Types in Patients With Non-small-cell Lung Cancer. Clinical lung cancer\| PubMed ID: 29338938	2018
Subjecting appropriate lung adenocarcinoma samples to next-generation sequencing-based molecular testing: challenges and possible solutions. Molecular oncology\| PubMed ID: 29518290	2018
Primary and acquired EGFR T790M-mutant NSCLC patients identified by routine mutation testing show different characteristics but may both respond to osimertinib treatment. Cancer letters\| PubMed ID: 29524556	2018
Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression. Oncotarget\| PubMed ID: 29552293	2018
Identification of MET exon14 skipping by targeted DNA- and RNA-based next-generation sequencing in pulmonary sarcomatoid carcinomas. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 30032818	2018
The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing. Journal of cancer research and clinical oncology\| PubMed ID: 30171333	2018
LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores. Nature communications\| PubMed ID: 30655516	2019
Concurrent Presence of ALK Rearrangement and MET Mutation in Lung Adenocarcinoma. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 30683300	2019
Outcome of chemotherapy with or without targeted agents in metastatic colorectal cancer patients with deficient DNA mismatch repair: A single center, cohort study. Asia-Pacific journal of clinical oncology\| PubMed ID: 30693649	2019
Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing. International journal of endocrinology\| PubMed ID: 30915113	2019
Major challenges in accurate mutation detection of multifocal lung adenocarcinoma by next-generation sequencing. Cancer biology & therapy\| PubMed ID: 31651223	2020
Distinct clinical phenotype and genetic testing strategy for Lynch syndrome in China based on a large colorectal cancer cohort. International journal of cancer\| PubMed ID: 32030746	2020
Intergenic Breakpoints Identified by DNA Sequencing Confound Targetable Kinase Fusion Detection in NSCLC. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 32151779	2020
[Correlation between the Expression of PD-L1 in Pleural Effusion of Lung Adenocarcinoma and the Clinicopathological Features and Molecular Changes]. Zhongguo fei ai za zhi = Chinese journal of lung cancer\| PubMed ID: 32209183	2020
Prevalence and characteristics of mutation in mismatch repair-deficient colorectal cancer. Journal of Cancer\| PubMed ID: 32328187	2020
Identification of second primary tumors from lung metastases in patients with esophageal squamous cell carcinoma using whole-exome sequencing. Theranostics\| PubMed ID: 32929369	2020
Risk Stratification Study of Indeterminate Thyroid Nodules with a next-generation Sequencing Assay with Residual ThinPrep® Material. Journal of Cancer\| PubMed ID: 33193891	2020
Potential Unreliability of Uncommon ALK, ROS1, and RET Genomic Breakpoints in Predicting the Efficacy of Targeted Therapy in NSCLC. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 33248323	2021
Identification of DNA methylation biomarkers for risk of liver metastasis in early-stage colorectal cancer. Clinical epigenetics\| PubMed ID: 34108011	2021
Different Clinicopathologic and Computed Tomography Imaging Characteristics of Primary and Acquired Mutations in Patients with Non-Small-Cell Lung Cancer. Cancer management and research\| PubMed ID: 34413682	2021
Exon 18 Mutations in Advanced Non-Small Cell Lung Cancer: A Real-World Study on Diverse Treatment Patterns and Clinical Outcomes. Frontiers in oncology\| PubMed ID: 34540680	2021
Hypertension Induced by Combination Therapy of Cancer: A Systematic Review and Meta-Analysis of Global Clinical Trials. Frontiers in pharmacology\| PubMed ID: 34552487	2021
ALK Rearrangement-Positive Pancreatic Cancer with Brain Metastasis Has Remarkable Response to ALK Inhibitors: A Case Report. Frontiers in oncology\| PubMed ID: 34568053	2021
Metastatic NSCLCs With Limited Tissues: How to Effectively Identify Driver Alterations to Guide Targeted Therapy in Chinese Patients. JTO clinical and research reports\| PubMed ID: 34590019	2021
mutation is positively correlated with C-Met protein expression: a study of 446 resected lung adenocarcinoma. Translational cancer research\| PubMed ID: 35116255	2021
Effectiveness of crizotinib in a patient with mesenchymal-epithelial transition overexpression/fluorescence in situ hybridization-negative/next-generation sequencing-negative advanced lung a... Translational cancer research\| PubMed ID: 35116804	2019
Sclerosing thymoma: a case report and literature review. Translational cancer research\| PubMed ID: 35117663	2020
The Lifted Veil of Uncommon EGFR Mutation p.L747P in Non-Small Cell Lung Cancer: Molecular Feature and Targeting Sensitivity to Tyrosine Kinase Inhibitors. Frontiers in oncology\| PubMed ID: 35223527	2022
First-line immunotherapy or angiogenesis inhibitor plus chemotherapy for -altered NSCLC: a retrospective real-world POLISH study. Therapeutic advances in medical oncology\| PubMed ID: 35251321	2022
Specific Exon 20 Gly776 Deletion-Insertions in Non-Small Cell Lung Cancer: Structural Analysis and Sensitivity to -Targeted Tyrosine Kinase Inhibitors. Frontiers in pharmacology\| PubMed ID: 35330827	2022
Clinicopathologic characteristics and diagnostic methods of rearrangement in Chinese non-small cell lung cancer patients. Translational lung cancer research\| PubMed ID: 35529790	2022
Reliability analysis of exonic-breakpoint fusions identified by DNA sequencing for predicting the efficacy of targeted therapy in non-small cell lung cancer. BMC medicine\| PubMed ID: 35534835	2022
First-line immunotherapy or angiogenesis inhibitor combined with chemotherapy for advanced non-small cell lung cancer with EGFR exon 20 insertions: Real-world evidence from China. Cancer medicine\| PubMed ID: 35608132	2023
Genomic and epigenomic profiles distinguish pulmonary enteric adenocarcinoma from lung metastatic colorectal cancer. EBioMedicine\| PubMed ID: 35901658	2022
Molecular characteristics of multifocal esophageal squamous cell carcinomas to discriminate multicentric origin from intramural metastasis. The Journal of pathology\| PubMed ID: 36098222	2022
Correlations of switch/sucrose nonfermentable complex mutations with clinical outcomes in advanced non-small cell lung cancer. Thoracic cancer\| PubMed ID: 36126963	2022
uncommon alterations in advanced non-small cell lung cancer and structural insights into sensitivity to diverse tyrosine kinase inhibitors. Frontiers in pharmacology\| PubMed ID: 36188595	2022
Developing an effective quality evaluation strategy of next-generation sequencing for accurate detecting non-small cell lung cancer samples with variable characteristics: a real-world clinic... Journal of cancer research and clinical oncology\| PubMed ID: 36305947	2023
Comparison of the Clinicopathological Characteristics and Prognosis of Esophageal Squamous Cell Carcinoma with Intramural Metastases and Multiple Primary Carcinomas. World journal of surgery\| PubMed ID: 36437350	2023
Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy in NSCLC. Frontiers of medicine\| PubMed ID: 37010729	2023
Ultra-rapid Idylla™ mutation screening followed by next-generation sequencing: An integrated solution to molecular diagnosis of non-small cell lung cancer. Frontiers in oncology\| PubMed ID: 37064089	2023
Primary pulmonary hyalinizing clear cell carcinoma with vocal-cord squamous cell carcinoma: a case report with systematic review. Diagnostic pathology\| PubMed ID: 37553667	2023
Pyrotinib plus antiangiogenic agents for HER2-altered advanced non-small cell lung cancer: A retrospective real-world study. Thoracic cancer\| PubMed ID: 37740599	2023
Efficacy and safety of immunotherapy combined with single-agent chemotherapy as second- or later-line therapy for metastatic non-small cell lung cancer. Frontiers in immunology\| PubMed ID: 37795095	2023
CD74/SLC34A2-ROS1 Fusion Variants Involving the Transmembrane Region Predict Poor Response to Crizotinib in NSCLC Independent of TP53 Mutations. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 38070598	2024
Real-world outcomes of chemoimmunotherapy and selective RET inhibitors in Chinese patients with RET fusion-positive non-small cell lung cancer. Heliyon\| PubMed ID: 38304763	2024
Erratum to: Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy in NSCLC. Frontiers of medicine\| PubMed ID: 38700643	2024
Liquid-based cytology specimens for next-generation sequencing in lung adenocarcinoma: challenges and evaluation of targeted therapy. BMC cancer\| PubMed ID: 38902688	2024
Single-cell exome sequencing reveals polyclonal seeding and TRPS1 mutations in colon cancer metastasis. Signal transduction and targeted therapy\| PubMed ID: 39307879	2024
GLI1, CDK4, and MDM2 Co-Amplification Gastric Plexiform Fibromyxoma: A Case Report and Literature Review. Genes, chromosomes & cancer\| PubMed ID: 39535850	2024
Calcified chondroid mesenchymal neoplasm: a clinicopathological and molecular analysis. Journal of clinical pathology\| PubMed ID: 39798957	2025
Pembrolizumab with Chemotherapy for Patients with Recurrent or Metastatic Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma: A Prospective Phase ll Study. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 39992644	2025
Pan-cancer analysis to character the clinicopathological and genomic features of KRAS-mutated patients in China. Journal of cancer research and clinical oncology\| PubMed ID: 40016583	2025
Diagnosis and treatment of colorectal liver metastases: Chinese expert consensus-based multidisciplinary team (2024 edition). Chinese medical journal\| PubMed ID: 40640089	2025
Clinicopathological features, risk model and prognosis of 115 cases of epithelioid hemangioendothelioma: A single-center study. Frontiers in oncology\| PubMed ID: 40919137	2025
Concurrent L858R and K860I mutations: PCR-negative but NGS-positive alterations that respond to inhibitors in non-small cell lung cancer. Journal of thoracic disease\| PubMed ID: 40950866	2025