Donald Peebles

EGA Institute for Women's Health, University College London (UCL)

Affiliated withUniversity College London (UCL)

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Effects of chronic hypoxia and protein malnutrition on growth in the developing chick. American journal of obstetrics and gynecology\| PubMed ID: 11854647	2002
Synergy between antenatal exposure to infection and intrapartum events in causation of perinatal brain injury at term. BJOG : an international journal of obstetrics and gynaecology\| PubMed ID: 12135207	2002
Severe preeclampsia and cerebral blood volume response to postural change. Obstetrics and gynecology\| PubMed ID: 12517651	2003
Cerebral hemoglobin concentration and oxygen saturation measured by intensity modulated optical spectroscopy in the human fetus during labor. Journal of perinatal medicine\| PubMed ID: 12530107	2002
Magnetic resonance proton spectroscopy and diffusion weighted imaging of chick embryo brain in ovo. Brain research. Developmental brain research\| PubMed ID: 12644253	2003
Urinary outflow obstruction increases apoptosis and deregulates Bcl-2 and Bax expression in the fetal ovine bladder. The American journal of pathology\| PubMed ID: 12651619	2003
The effect of systemic administration of lipopolysaccharide on cerebral haemodynamics and oxygenation in the 0.65 gestation ovine fetus in utero. BJOG : an international journal of obstetrics and gynaecology\| PubMed ID: 12892685	2003
-455G/A beta-fibrinogen gene polymorphism, factor V Leiden, prothrombin G20210A mutation and MTHFR C677T, and placental vascular complications. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis\| PubMed ID: 15091001	2004
Fetal consequences of chronic substrate deprivation. Seminars in fetal & neonatal medicine\| PubMed ID: 15691773	2004
Recreational drugs and fetal gastroschisis: maternal hair analysis in the peri-conceptional period and during pregnancy. BJOG : an international journal of obstetrics and gynaecology\| PubMed ID: 16045512	2005
Targeting the respiratory muscles of fetal sheep for prenatal gene therapy for Duchenne muscular dystrophy. American journal of obstetrics and gynecology\| PubMed ID: 16157120	2005
Growth restriction and the cerebral metabolic response to acute hypoxia of chick embryos in-ovo: a proton magnetic resonance spectroscopy study. Brain research. Developmental brain research\| PubMed ID: 16223529	2005
N-methyl-isobutyl-amiloride ameliorates brain injury when commenced before hypoxia ischemia in neonatal mice. Pediatric research\| PubMed ID: 16439583	2006
Hypothesis: the placental 'steal' phenomenon - a possible hazard of amnioreduction. Fetal diagnosis and therapy\| PubMed ID: 16601343	2006
Superficial brain is cooler in small piglets: neonatal hypothermia implications. Annals of neurology\| PubMed ID: 17048261	2006
Radiotelemetered urodynamics of obstructed ovine fetal bladders: correlations with ex vivo cystometry and renal histopathology. BJU international\| PubMed ID: 17355367	2007
"Therapeutic time window" duration decreases with increasing severity of cerebral hypoxia-ischaemia under normothermia and delayed hypothermia in newborn piglets. Brain research\| PubMed ID: 17475224	2007
Gene therapy for the fetus: is there a future? Best practice & research. Clinical obstetrics & gynaecology\| PubMed ID: 17900991	2008
Fetal gene transfer. Current opinion in molecular therapeutics\| PubMed ID: 17932807	2007
Greater hypoxia-induced cell death in prenatal brain after bacterial-endotoxin pretreatment is not because of enhanced cerebral energy depletion: a chicken embryo model of the intrapartum re... Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 18030303	2008
Monocyte major histocompatibility complex class II expression in term and preterm labor. Obstetrics and gynecology\| PubMed ID: 18055729	2007
Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development. Glia\| PubMed ID: 19544386	2010
Doppler ultrasonography for the noninvasive measurement of uterine artery volume blood flow through gestation in the pregnant sheep. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 19767542	2010
Use of high intensity adjusted dose low molecular weight heparin in women with mechanical heart valves during pregnancy: a single-center experience. Haematologica\| PubMed ID: 19880782	2009
Differing prevalence and diversity of bacterial species in fetal membranes from very preterm and term labor. PloS one\| PubMed ID: 19997613	2009
Ultrasonographic development of the fetal sheep stomach and evaluation of early gestation ultrasound-guided in utero intragastric injection. Taiwanese journal of obstetrics & gynecology\| PubMed ID: 20466288	2010
Pregnancy outcome in women with congenital heart disease and residual haemodynamic lesions of the right ventricular outflow tract. European heart journal\| PubMed ID: 20511325	2010
Recombinant adeno-associated virus-mediated in utero gene transfer gives therapeutic transgene expression in the sheep. Human gene therapy\| PubMed ID: 20919876	2011
In utero gene transfer to the mouse nervous system. Biochemical Society transactions\| PubMed ID: 21118113	2010
Telemetric monitoring of fetal blood pressure and heart rate in the freely moving pregnant sheep: a feasibility study. Laboratory animals\| PubMed ID: 21127076	2011
TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 21135813	2011
Stable human FIX expression after 0.9G intrauterine gene transfer of self-complementary adeno-associated viral vector 5 and 8 in macaques. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21629224	2011
Distribution of pH changes in mouse neonatal hypoxic-ischaemic insult. Developmental neuroscience\| PubMed ID: 22343485	2011
Immune status in very preterm neonates. Pediatrics\| PubMed ID: 22451711	2012
Animal models for prenatal gene therapy: choosing the right model. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22648773	2012
Animal models for prenatal gene therapy: the sheep model. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22648775	2012
Monitoring for potential adverse effects of prenatal gene therapy: use of large animal models with relevance to human application. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22648778	2012
Pregnancy outcome and management of women with an implantable cardioverter defibrillator: a single centre experience. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology\| PubMed ID: 22744770	2012
Recent advances in fetal gene therapy. Therapeutic delivery\| PubMed ID: 22826854	2011
Perinatal gene delivery to the CNS. Therapeutic delivery\| PubMed ID: 22826856	2011
Paternal metabolic and cardiovascular risk factors for fetal growth restriction: a case-control study. Diabetes care\| PubMed ID: 23315598	2013
Paternally expressed, imprinted insulin-like growth factor-2 in chorionic villi correlates significantly with birth weight. PloS one\| PubMed ID: 24454871	2014
Uteroplacental adenovirus vascular endothelial growth factor gene therapy increases fetal growth velocity in growth-restricted sheep pregnancies. Human gene therapy\| PubMed ID: 24593228	2014
Risk of preterm delivery with increasing depth of excision for cervical intraepithelial neoplasia in England: nested case-control study. BMJ (Clinical research ed.)\| PubMed ID: 25378384	2014
Term and preterm labour are associated with distinct microbial community structures in placental membranes which are independent of mode of delivery. Placenta\| PubMed ID: 25458966	2014
Antenatal tests of fetal wellbeing. Seminars in fetal & neonatal medicine\| PubMed ID: 25936927	2015
Specific Lipopolysaccharide Serotypes Induce Differential Maternal and Neonatal Inflammatory Responses in a Murine Model of Preterm Labor. The American journal of pathology\| PubMed ID: 26212908	2015
Is variation in copy number of the human beta defensin gene cluster associated with preterm birth? Lancet (London, England)\| PubMed ID: 26312869	2015
Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) reduces neonatal hypoxic-ischaemic brain damage. Journal of neurochemistry\| PubMed ID: 26669927	2016
Gene Targeting to the Uteroplacental Circulation of Pregnant Guinea Pigs. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 26865541	2016
Peri- and Postnatal Effects of Prenatal Adenoviral VEGF Gene Therapy in Growth-Restricted Sheep. Biology of reproduction\| PubMed ID: 27103444	2016
Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics. BMC medicine\| PubMed ID: 27291689	2016
EVERREST prospective study: a 6-year prospective study to define the clinical and biological characteristics of pregnancies affected by severe early onset fetal growth restriction. BMC pregnancy and childbirth\| PubMed ID: 28114884	2017
Perinatal risk factors for neonatal encephalopathy: an unmatched case-control study. Archives of disease in childhood. Fetal and neonatal edition\| PubMed ID: 28780500	2018
Neuroprotection of the hypoxic-ischemic mouse brain by human CD117CD90CD105 amniotic fluid stem cells. Scientific reports\| PubMed ID: 29402914	2018
Embryonic Stem Cell-Derived Mesenchymal Stem Cells (MSCs) Have a Superior Neuroprotective Capacity Over Fetal MSCs in the Hypoxic-Ischemic Mouse Brain. Stem cells translational medicine\| PubMed ID: 29489062	2018
Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths. Circulation. Genomic and precision medicine\| PubMed ID: 29874177	2018
Towards computer-assisted TTTS: Laser ablation detection for workflow segmentation from fetoscopic video. International journal of computer assisted radiology and surgery\| PubMed ID: 29951938	2018
Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice. The American journal of pathology\| PubMed ID: 30036519	2018
The DESiGN trial (DEtection of Small for Gestational age Neonate), evaluating the effect of the Growth Assessment Protocol (GAP): study protocol for a randomised controlled trial. Trials\| PubMed ID: 30832739	2019
Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy. Scientific reports\| PubMed ID: 31308390	2019
Predictive value of cervical cytokine, antimicrobial and microflora levels for pre-term birth in high-risk women. Scientific reports\| PubMed ID: 31375740	2019
Fetal surgery for open spina bifida. The obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists\| PubMed ID: 31787844	2019
Cervical Gene Delivery of the Antimicrobial Peptide, Human β-Defensin (HBD)-3, in a Mouse Model of Ascending Infection-Related Preterm Birth. Frontiers in immunology\| PubMed ID: 32117260	2020
Serial blood cytokine and chemokine mRNA and microRNA over 48 h are insult specific in a piglet model of inflammation-sensitized hypoxia-ischaemia. Pediatric research\| PubMed ID: 32521540	2021
A Systematic Review and Meta-analysis of the Use of High-Fidelity Simulation in Obstetric Ultrasound. Simulation in healthcare : journal of the Society for Simulation in Healthcare\| PubMed ID: 32675735	2021
Comparison of Efficiency and Function of Vascular Endothelial Growth Factor Adenovirus Vectors in Endothelial Cells for Gene Therapy of Placental Insufficiency. Human gene therapy\| PubMed ID: 32988220	2020
Dimensionless squared jerk: An objective differential to assess experienced and novice probe movement in obstetric ultrasound. Prenatal diagnosis\| PubMed ID: 33103808	2021
Biometric assessments of the posterior fossa by fetal MRI: A systematic review. Prenatal diagnosis\| PubMed ID: 33251640	2021
Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia-ischemia. Pediatric research\| PubMed ID: 34050269	2022
Development of standard definitions and grading for Maternal and Fetal Adverse Event Terminology. Prenatal diagnosis\| PubMed ID: 34550624	2022
Deep learning-based plane pose regression in obstetric ultrasound. International journal of computer assisted radiology and surgery\| PubMed ID: 35489005	2022
Evaluation of the Growth Assessment Protocol (GAP) for antenatal detection of small for gestational age: The DESiGN cluster randomised trial. PLoS medicine\| PubMed ID: 35727800	2022
Screening policies for cytomegalovirus in pregnancy in the era of antivirals. Lancet (London, England)\| PubMed ID: 35964603	2022
Effect of the Growth Assessment Protocol on the DEtection of Small for GestatioNal age fetus: process evaluation from the DESiGN cluster randomised trial. Implementation science : IS\| PubMed ID: 36064428	2022
Antenatal detection of large-for-gestational-age fetuses following implementation of the Growth Assessment Protocol: secondary analysis of a randomised control trial. BJOG : an international journal of obstetrics and gynaecology\| PubMed ID: 36999234	2023
Neonatal outcomes following early fetal growth restriction: a subgroup analysis of the EVERREST study. Archives of disease in childhood. Fetal and neonatal edition\| PubMed ID: 37185272	2023
Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction. The Journal of clinical investigation\| PubMed ID: 37712421	2023
Probe motion during mid-trimester fetal anomaly scan in the clinical setting: A prospective observational study. European journal of obstetrics, gynecology, and reproductive biology\| PubMed ID: 38705008	2024
Ultrasound Plane Pose Regression: Assessing Generalized Pose Coordinates in the Fetal Brain. IEEE transactions on medical robotics and bionics\| PubMed ID: 38881728	2024
Ascending Vaginal Infection in Mice Induces Preterm Birth and Neonatal Morbidity. The American journal of pathology\| PubMed ID: 39892780	2025
Economic Impact of Severe Early-Onset Foetal Growth Restriction: A Multicentre Prospective Cohort Study. BJOG : an international journal of obstetrics and gynaecology\| PubMed ID: 40552422	2025
Parvovirus: Conservative management of fetal anemia and hydrops. Acta obstetricia et gynecologica Scandinavica\| PubMed ID: 41028928	2025