collection-human-follicular-fluid-follicle-somatic-cells-immature

Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing<em> In Vitro </em>Fertilization

Human ovary follicular contents, including follicular fluid (FF), oocytes, cumulus cells, and somatic cells, offer a powerful yet underutilized ...

Northwestern Medicine Center for Fertility and Reproductive Medicine

Are the molecular signatures of cumulus cells (CCs) and follicular fluid (FF) of adolescents undergoing fertility preservation differ from that of reproductively adult oocyte donors?

The oocyte microenvironment is altered in adolescents compared to oocyte donors.

To investigate follicular fluid (FF) phthalate levels in adolescents undergoing fertility preservation compared to oocyte donors and explore its association with ovarian reserve and cumulus cell gene expression.

Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome.

Do the molecular signatures of cumulus cells (CCs) and follicular fluid (FF) of adolescents undergoing fertility preservation differ from that of oocyte donors?

To investigate the follicular fluid (FF) phthalate levels in adolescents undergoing fertility preservation compared with oocyte donors and explore its association with ovarian reserve and cumulus cell (CC) gene expression.

Article	Year
The oocyte microenvironment is altered in adolescents compared to oocyte donors. bioRxiv : the preprint server for biology\| PubMed ID: 38617323	2024
Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome. bioRxiv : the preprint server for biology\| PubMed ID: 38645121	2024
The oocyte microenvironment is altered in adolescents compared to oocyte donors. Human reproduction open\| PubMed ID: 39211054	2024
Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome. F&S science\| PubMed ID: 39515754	2025

Anna Kleinhans

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