Palak Panchal

Chemical Biology Program, Memorial Sloan Kettering Cancer Center

Affiliated withMemorial Sloan Kettering Cancer Center

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
The epichaperome is an integrated chaperome network that facilitates tumour survival. Nature\| PubMed ID: 27706135	2016
Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors. The Journal of experimental medicine\| PubMed ID: 29141866	2018
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction. Nature communications\| PubMed ID: 31949159	2020
Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone. Cell reports\| PubMed ID: 32610141	2020
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia. NPJ precision oncology\| PubMed ID: 34040147	2021
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system. Nature communications\| PubMed ID: 34344873	2021
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer. Communications biology\| PubMed ID: 34824367	2021
Synthesis of I-labeled epichaperome probes and assessment in visualizing pathologic protein-protein interaction networks in tumor bearing mice. STAR protocols\| PubMed ID: 35496791	2022
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view. Structure (London, England : 1993)\| PubMed ID: 37343552	2023
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation. Nature communications\| PubMed ID: 37353488	2023
Use of Native-PAGE for the Identification of Epichaperomes in Cell Lines. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 37540435	2023
Unraveling the Mechanism of Epichaperome Modulation by Zelavespib: Biochemical Insights on Target Occupancy and Extended Residence Time at the Site of Action. Biomedicines\| PubMed ID: 37892973	2023
Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation. Research square\| PubMed ID: 38645031	2024
Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative Disorders. Biomedicines\| PubMed ID: 38927459	2024
Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation. Nature communications\| PubMed ID: 39414766	2024
Systems-Level Interactome Mapping Reveals Actionable Protein Network Dysregulation Across the Alzheimer's Disease Spectrum. Research square\| PubMed ID: 39989971	2025