integrated-pcr-based-molecular-detection-system-for-simultaneous

Integrated PCR-Based Molecular Detection System for the Simultaneous Detection of Four Zoonotic Intestinal Parasites from Multiple Sources

Infectious diseases are critical factors affecting human health, economic development, and social stability. Among them, zoonotic intestinal parasitic ...

Jiangsu Provincial Center for Disease Control and Prevention

Spermatogonial stem cells and organ engineering research has raised new hope in infertility treatment. Spermatogenesis is a complex physiological process. To observe the proliferation ability and differentiation tendency of mice spermatogonial stem cells (SSCs), to study the effect of regulating the Wnt signaling pathway on the proliferation and differentiation of SSCs, and to provide a valuable basis for the clinical application of SSCs.

The effect of regulating the Wnt signaling pathway on the proliferation and differentiation of spermatogonial stem cells.

 To investigate the infection status, species composition, and genetic diversity of  in local rodent populations in coastal mudflat wetland habitats in eastern Jiangsu Province of China.  From March to June 2023, rodents were captured in mudflat wetlands of Dongtai and Tinghu Counties, Eastern China. Rodent species were identified, and nucleic acids were extracted from liver and spleen tissues. The mitochondrial cytochrome b (mt-) gene was amplified by PCR, while -specific citrate synthase () and 16S rRNA genes were amplified by semi-nested PCR. Phylogenetic and homology analyses were conducted to identify rodent and  species.  Among 29 captured rodents, 26 were  and 3 were . Phylogenetic analysis of the mt- gene divided  into 7 lineages, each linked to geographically diverse  populations. Six  rodents tested positive for , with a positivity rate of 20.69%. Phylogenetic analyses revealed three  species: , , and one undetermined species. The infected  strains clustered into three evolutionary branches based on  and 16S rRNA genes.  This study provides the first evidence of  infection among rodent populations in wetland habitats along China's eastern coast. The region harbors diverse rodent species, with a high  infection rate, and at least three species were identified, including a potential novel species.

Prevalence, Species Characterization, and Genetic Diversity of  Infections in Rodents From Mudflat Wetlands Along the Eastern Coast of Jiangsu Province in China.

Article	Year
The effect of regulating the Wnt signaling pathway on the proliferation and differentiation of spermatogonial stem cells. Annals of translational medicine\| PubMed ID: 32953803	2020
Prevalence, Species Characterization, and Genetic Diversity of Infections in Rodents From Mudflat Wetlands Along the Eastern Coast of Jiangsu Province in China. Journal of tropical medicine\| PubMed ID: 40313357	2025

Haiyan Peng

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