Lukas Sommer

Institute of Anatomy, University of Zurich

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes & development\| PubMed ID: 15741317	2005
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. The Journal of cell biology\| PubMed ID: 15837799	2005
Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18184786	2008
Development of the Schwann cell lineage: from the neural crest to the myelinated nerve. Glia\| PubMed ID: 18803317	2008
Chemokines in neuroectodermal development and their potential implication in cancer stem cell-driven metastasis. Seminars in cancer biology\| PubMed ID: 19084599	2009
Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell stem cell\| PubMed ID: 19265663	2009
Multiple lineage-specific roles of Smad4 during neural crest development. Developmental biology\| PubMed ID: 19361496	2009
Stage- and area-specific control of stem cells in the developing nervous system. Current opinion in genetics & development\| PubMed ID: 19748262	2009
Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development (Cambridge, England)\| PubMed ID: 20573699	2010
Transforming growth factor β-mediated Sox10 suppression controls mesenchymal progenitor generation in neural crest stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 21308864	2011
Generation of melanocytes from neural crest cells. Pigment cell & melanoma research\| PubMed ID: 21310010	2011
Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth. Cancer research\| PubMed ID: 21393506	2011
Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 21425410	2011
The genetic basis of craniofacial and dental abnormalities. Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia\| PubMed ID: 21861247	2011
Engineering melanoma progression in a humanized environment in vivo. The Journal of investigative dermatology\| PubMed ID: 21881586	2012
Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model. Neoplasia (New York, N.Y.)\| PubMed ID: 22028624	2011
Probing transcription-specific outputs of β-catenin in vivo. Genes & development\| PubMed ID: 22190459	2011
Mesenchymal stem cells and neural crest stem cells from adult bone marrow: characterization of their surprising similarities and differences. Cellular and molecular life sciences : CMLS\| PubMed ID: 22349262	2012
Tumor cell plasticity and angiogenesis in human melanomas. PloS one\| PubMed ID: 22442699	2012
Temporal control of neural crest lineage generation by Wnt/β-catenin signaling. Development (Cambridge, England)\| PubMed ID: 22573620	2012
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nature cell biology\| PubMed ID: 22772081	2012
In vivo tumorigenesis was observed after injection of in vitro expanded neural crest stem cells isolated from adult bone marrow. PloS one\| PubMed ID: 23071568	2012
Testing the cancer stem cell hypothesis in melanoma: the clinics will tell. Cancer letters\| PubMed ID: 23073475	2013
Smad4 and Trim33/Tif1γ redundantly regulate neural stem cells in the developing cortex. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 23765158	2014
A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors. PLoS genetics\| PubMed ID: 23935512	2013
Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural stem cell specification into oligodendrocytes and glutamatergic neurons. Stem cells (Dayton, Ohio)\| PubMed ID: 24449255	2014
Ezh2 is required for neural crest-derived cartilage and bone formation. Development (Cambridge, England)\| PubMed ID: 24496623	2014
Open questions: development of tumor cell heterogeneity and its implications for cancer treatment. BMC biology\| PubMed ID: 24597924	2014
An Aggressive Hypoxia Related Subpopulation of Melanoma Cells is TRP-2 Negative. Translational oncology\| PubMed ID: 24746711	2014
HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24760871	2014
Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells. Oncotarget\| PubMed ID: 24947326	2014
Reinventing the neural crest: direct reprogramming makes iNCCs. Cell stem cell\| PubMed ID: 25280213	2014
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors. Nature communications\| PubMed ID: 25609585	2015
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma. PLoS genetics\| PubMed ID: 25629959	2015
Premigratory and migratory neural crest cells are multipotent in vivo. Cell stem cell\| PubMed ID: 25748934	2015
Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation. BMC biology\| PubMed ID: 25885041	2015
Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma. Genome biology\| PubMed ID: 25885555	2015
Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC biology\| PubMed ID: 26621269	2015
In Vitro Derivation of Melanocytes from Embryonic Neural Crest Stem Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26659800	2015
Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2. Science translational medicine\| PubMed ID: 27903862	2016
The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy. Cell reports\| PubMed ID: 28746871	2017
Quo vadis: tracing the fate of neural crest cells. Current opinion in neurobiology\| PubMed ID: 28753439	2017
Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes. Cell stem cell\| PubMed ID: 29033351	2017
Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nature communications\| PubMed ID: 29133867	2017
low neurotrophin receptor CD271 regulates phenotype switching in melanoma. Nature communications\| PubMed ID: 29215016	2017
Injury-activated glial cells promote wound healing of the adult skin in mice. Nature communications\| PubMed ID: 29339718	2018
Publisher Correction: The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma. Nature communications\| PubMed ID: 29358574	2018
Cre-driver lines used for genetic fate mapping of neural crest cells in the mouse: An overview. Genesis (New York, N.Y. : 2000)\| PubMed ID: 29673028	2018
Injury and stress responses of adult neural crest-derived cells. Developmental biology\| PubMed ID: 29778801	2018
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation. Cancer cell\| PubMed ID: 30008323	2018
Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell stem cell\| PubMed ID: 30951662	2019
SMAD signaling promotes melanoma metastasis independently of phenotype switching. The Journal of clinical investigation\| PubMed ID: 31039140	2019
Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nature communications\| PubMed ID: 31097699	2019
Reemergence of neural crest stem cell-like states in melanoma during disease progression and treatment. Stem cells translational medicine\| PubMed ID: 33258291	2021
Retraction Note: Mesenchymal stem cells and neural crest stem cells from adult bone marrow: characterization of their surprising similarities and differences. Cellular and molecular life sciences : CMLS\| PubMed ID: 33963879	2021
NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence. Nature communications\| PubMed ID: 34349124	2021
Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4. Nature communications\| PubMed ID: 34417458	2021
Loss of YY1, a Regulator of Metabolism in Melanoma, Drives Melanoma Cell Invasiveness and Metastasis Formation. Frontiers in cell and developmental biology\| PubMed ID: 35693944	2022
Schwann cell precursors: a hub of neural crest development. The EMBO journal\| PubMed ID: 35894449	2022
Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell stem cell\| PubMed ID: 36113462	2022
Neural crest cells hijack pluripotent stem cell factors to realize their developmental potential. Developmental cell\| PubMed ID: 36220078	2022
Escape from NK cell tumor surveillance by NGFR-induced lipid remodeling in melanoma. Science advances\| PubMed ID: 36638181	2023
Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation. The Journal of biological chemistry\| PubMed ID: 37992803	2024
Monitoring melanoma patients on treatment reveals a distinct macrophage population driving targeted therapy resistance. Cell reports. Medicine\| PubMed ID: 38942020	2024
Fibrolytic vaccination against ADAM12 reduces desmoplasia in preclinical pancreatic adenocarcinomas. EMBO molecular medicine\| PubMed ID: 39478152	2024
TGFβ signaling sensitizes MEKi-resistant human melanoma to targeted therapy-induced apoptosis. Cell death & disease\| PubMed ID: 39709491	2024
A novel murine model for sporadic, malignant peripheral nerve sheath tumors, driven by BrafV600E and Pten loss. Disease models & mechanisms\| PubMed ID: 41063628	2025