Marc-Olivier Deguise

Sinclair Centre for Regenerative Medicine, Ottawa Hospital Research Institute

Affiliated withOttawa Hospital Research Institute Children's Hospital of Eastern Ontario University of Ottawa

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Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy. Human molecular genetics\| PubMed ID: 24691550	2014
Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy. Scientific reports\| PubMed ID: 27349908	2016
Oligodendrocyte development and CNS myelination are unaffected in a mouse model of severe spinal muscular atrophy. Human molecular genetics\| PubMed ID: 28069797	2017
Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice. Human molecular genetics\| PubMed ID: 28108555	2017
New insights into SMA pathogenesis: immune dysfunction and neuroinflammation. Annals of clinical and translational neurology\| PubMed ID: 28695153	2017
Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice. EBioMedicine\| PubMed ID: 29735415	2018
Abnormal fatty acid metabolism is a core component of spinal muscular atrophy. Annals of clinical and translational neurology\| PubMed ID: 31402618	2019
Low fat diets increase survival of a mouse model of spinal muscular atrophy. Annals of clinical and translational neurology\| PubMed ID: 31608604	2019
Blood Flow to the Spleen is Altered in a Mouse Model of Spinal Muscular Atrophy. Journal of neuromuscular diseases\| PubMed ID: 32333548	2020
Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy. EBioMedicine\| PubMed ID: 32339936	2020
SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 33545428	2021
Metabolic Dysfunction in Spinal Muscular Atrophy. International journal of molecular sciences\| PubMed ID: 34072857	2021
Resident Match During the COVID Pandemic: How Have Neurology Programs Adapted? - A Survey. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques\| PubMed ID: 35189987	2023
Survival motor neuron protein deficiency alters microglia reactivity. Glia\| PubMed ID: 35373853	2022
Central and peripheral delivered AAV9-SMN are both efficient but target different pathomechanisms in a mouse model of spinal muscular atrophy. Gene therapy\| PubMed ID: 35462564	2022
Suppression of the necroptotic cell death pathways improves survival in mice. Frontiers in cellular neuroscience\| PubMed ID: 35990890	2022
SMN depletion impairs skeletal muscle formation and maturation in a mouse model of SMA. Human molecular genetics\| PubMed ID: 39505369	2025
Liver SMN restoration rescues the Smn mouse model of spinal muscular atrophy. EBioMedicine\| PubMed ID: 39515026	2024
Skeletal Muscle Mitochondrial and Autophagic Dysregulation Are Modifiable in Spinal Muscular Atrophy. Journal of cachexia, sarcopenia and muscle\| PubMed ID: 39901351	2025
Cell-based therapies in preclinical models of necrotizing enterocolitis: a systematic review and meta-analysis. Stem cells translational medicine\| PubMed ID: 40036304	2025
NIPPV vs CPAP: Lessons from meta-analyses. Seminars in perinatology\| PubMed ID: 40055099	2025
The Role of Mesenchymal Stromal Cells in the Treatment of Bronchopulmonary Dysplasia: A Multi-Prong Approach for a Heterogeneous Disease. Comprehensive Physiology\| PubMed ID: 40853849	2025