molecular-mechanism-hydroxyl-safflower-yellow-knee-osteoarthritis

Molecular Mechanism of Hydroxyl Safflower Yellow A in Knee Osteoarthritis through Modulation of Autophagy <em>via</em> Inhibition of the HIF-1&#945;/BNIP3 Pathway

The reduction of autophagy in cartilage tissue is closely linked to the development of knee osteoarthritis (KOA), yet the mechanisms by which Hydroxyl ...

isolation-validation-podoplanin-positive-mesenchymal-stem-cell

Isolation and Validation of Podoplanin-positive Mesenchymal Stem Cell Subpopulations Using an Indirect Magnetic Bead Strategy

The study of functional heterogeneity in mesenchymal stem cells relies on the efficient isolation of specific subpopulations (e.g., podoplanin ...

Zhanjiang Central People's Hospital

The Sixth Affiliated Hospital, Sun Yat-sen University

Decreased ovarian reserve function is an ovarian hypofunction disease that occurs in women before 40 years of age, leading to a decline in fertility and perimenopausal symptoms, such as irregular menstruation, amenorrhea, infertility, decreased libido, and autonomic nervous dysfunction. Fenmatong (FMT) is a compound mixture of estradiol tablets and estradiol didroxyprogesterone tablets, which can improve ovarian reserve function by supplementation of exogenous estrogen. However, this treatment has also been shown to cause breast pain, gastrointestinal discomfort, irregular vaginal bleeding, and changes in sexual desire. In severe cases, FMT can promote the development of breast cancer, endometrial cancer, and venous embolic disease.

ArticleTotal : 2	Year
Publication title	2025
Publication title	2026

Haofan Chen

Biography

JoVE Journal Publications

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