delineating-role-alpha-waves-exercise-induced-neural-changes-through

Delineating the Role of Alpha Waves in Exercise-induced Neural Changes through Resting-state EEG

Exercise intervention demonstrates unique potential in treating emotional dysregulation, yet the ambiguity of its neuromodulation targets hinders the ...

Wuhan Sports University

Depression is associated with functional brain impairments, although comprehensive studies remain limited. This study reviews neural mechanisms underlying cognitive impairment in depression and identifies associated activation abnormalities in brain regions. The study also explores the underlying neural processes of cognitive benefits of exercise intervention for depression. Executive function impairments, including working memory, inhibitory control and cognitive flexibility are associated with frontal cortex and anterior cingulate areas, especially dorsolateral prefrontal cortex. Depression is associated with certain neural impairments of reward processing, especially orbitofrontal cortex, prefrontal cortex, nucleus accumbens and other striatal regions. Depressed patients exhibit decreased activity in the hippocampus during memory function. Physical exercise has been found to enhance memory function, executive function, and reward processing in depression patients by increasing functional brain regions and the brain-derived neurotrophic factor (BDNF) as a nutritional factor also plays a key role in exercise intervention. The study documents neurophysiological mechanisms behind exercise intervention's improved functions. In summary, the study provides insights into neural mechanisms underlying cognitive impairments in depression and the effectiveness of exercise as a treatment.

Neural mechanisms underlying cognitive impairment in depression and cognitive benefits of exercise intervention.

Anxiety is known to significantly impair cognitive function, particularly attentional control. While exercise has been demonstrated to alleviate these cognitive deficits, the precise neural mechanisms underlying these effects remain poorly understood. This study examines the effects of exercise on attentional control in individuals with high trait anxiety, based on attentional control theory, which suggests that such individuals have reduced top-down attention. Thirty-eight participants were randomly assigned to either an exercise group or a reading group. The exercise group engaged in 30 min of moderate-intensity cycling, while the reading group spent 30 min reading quietly. In Experiment 1, goal-directed attention was assessed using a cue-object paradigm, and in Experiment 2, inhibitory control was evaluated through a visual search task. EEG data indicated that the exercise group exhibited significantly larger Pd components in both experiments, suggesting enhanced attentional focus and improved inhibition of distractors. These findings suggest that aerobic exercise enhances top-down attentional processes, particularly goal-directed attention and distractor inhibition, offering potential as an intervention for individuals with high trait anxiety.

Article	Year
Neural mechanisms underlying cognitive impairment in depression and cognitive benefits of exercise intervention. Behavioural brain research\| PubMed ID: 39182624	2025
The effects of aerobic exercise on goal-directed attention and inhibitory control in individuals with high trait anxiety: an EEG study. BMC psychology\| PubMed ID: 39885607	2025

Zhidong Zhuang

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