primary-alk-negative-anaplastic-large-cell-lymphoma-mimicking-septic

Primary ALK-Negative Anaplastic Large Cell Lymphoma Mimicking Septic Arthritis in a Diabetic Patient: Diagnostic and Therapeutic Challenges

Anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL) is a rare, aggressive subtype of peripheral T-cell lymphoma that ...

Hangzhou Xiaoying Community Health Service Center

Adult-onset Still's disease (AOSD) is a systemic autoinflammatory disorder characterized by unpredictable multi-organ involvement. Although gastrointestinal complications are uncommon in AOSD, they can be life-threatening and present significant diagnostic and management challenges.

Fatal Acute Intestinal Obstruction with Hemophagocytic Lymphohistiocytosis and Multiple Organ Failure in Adult-Onset Still's Disease: A Rare Case Report.

Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a lifesaving intervention for severe respiratory failure; however, its effectiveness depends on accurate cannulation-patients with anatomical variations present with significant challenges during the procedure.

Rare complication of extracorporeal membrane oxygenation cannula misplacement into the hepatic vein: A case report.

COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a respiratory illness with high mortality, especially among critically ill patients. The Extracorporeal Life Support Organization (ELSO) COVID-19 Interim Guidelines recommend extracorporeal membrane oxygenation (ECMO) for severe COVID-19 cases when the partial pressure of oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio remains below 80 mmHg despite conventional treatments. We present the case of a 62-year-old male with severe COVID-19 pneumonia who required veno-venous ECMO (V-V ECMO). During his treatment, he experienced an acute myocardial infarction, necessitating percutaneous coronary intervention and stent placement. Although initially a candidate for lung transplantation, complications related to myocardial infarction and heart failure led to delays. Management of anticoagulation and antiplatelet therapy was further complicated by thrombocytopenia secondary to both infection and ECMO therapy. Nevertheless, the patient remained on ECMO for 124 days without oxygenator replacement or significant bleeding events. This case underscores the successful long-term use of V-V ECMO in the face of COVID-19, myocardial infarction, and thrombocytopenia, emphasizing the value of multidisciplinary teamwork and individualized treatment strategies.

Article	Year
Fatal Acute Intestinal Obstruction with Hemophagocytic Lymphohistiocytosis and Multiple Organ Failure in Adult-Onset Still's Disease: A Rare Case Report. Journal of inflammation research\| PubMed ID: 40255663	2025
Rare complication of extracorporeal membrane oxygenation cannula misplacement into the hepatic vein: A case report. World journal of gastrointestinal surgery\| PubMed ID: 40502522	2025
Prolonged ECMO Management (124 Days) in a Severe COVID-19 Patient Complicated by Acute Myocardial Infarction and Thrombocytopenia: A Case Report. Infection and drug resistance\| PubMed ID: 40620277	2025

Xuejia Pan

Biography

JoVE Journal Publications

Other Publications