a-traditional-chinese-medicine-characteristic-therapy-for-erectile

A Traditional Chinese Medicine Characteristic Therapy for Erectile Dysfunction: Acupuncture

Erectile dysfunction (ED) is a common disease of the male reproductive system, which seriously affects the quality of life of patients and their partners. ...

hospital of chengdu university of traditional chinese medicine

 Previous observational studies have investigated the association between sleep-related traits and male fertility; however, conclusive evidence of a causal connection is lacking. This study aimed to explore the causal relationship between sleep and male fertility using Mendelian randomisation.  Eight sleep-related traits (chronotype, sleep duration, insomnia, snoring, dozing, daytime nap, oversleeping, and undersleeping) and three descriptors representing male fertility (male infertility, abnormal sperm, and bioavailable testosterone levels) were selected from published Genome-Wide Association Studies. The causal relationship between sleep-related traits and male fertility was evaluated using multiple methods, including inverse variance weighting (IVW), weighted median, Mendelian randomisation-Egger, weighted model, and simple model through two-sample Mendelian randomisation analysis. Mendelian randomisation-Egger regression was used to assess pleiotropy, Cochrane's Q test was employed to detect heterogeneity, and a leave-one-out sensitivity analysis was conducted.  Genetically-predicted chronotype (IVW,OR = 1.07; 95%CL = 1.04-1.12;  = 0.0002) was suggestively associated with bioavailable testosterone levels. However, using the IVW method, we found no evidence of a causal association between other sleep traits and male fertility.  This study found that chronotype affects testosterone secretion levels. However, further studies are needed to explain this mechanism.

Association of sleep traits with male fertility: a two-sample Mendelian randomization study.

Overactive bladder (OAB) is a common lower urinary tract symptom of bladder storage dysfunction. Numerous studies have evaluated the efficacy and safety of acupuncture therapy for overactive bladder, but clinical programs and data were largely inconsistent. Therefore, it is necessary to summarize and analyze the published clinical research data in the field. We aimed to perform an umbrella review of systematic reviews and meta-analyses (SRs/MAs) to evaluate the efficacy and safety of acupuncture therapy.

Article	Year
Association of sleep traits with male fertility: a two-sample Mendelian randomization study. Frontiers in genetics\| PubMed ID: 38456015	2024
Acupuncture therapy of overactive bladder: An umbrella review and meta-analysis. Arab journal of urology\| PubMed ID: 39776552	2025

Shikuan Lu

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