Yujiro Hayashi

Enteric Neuroscience Program and Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science

Affiliated withMayo Clinic College of Medicine and Science

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2025
Publication title	2026

Other Publications

Article	Year
Cellular pathogenesis of diabetic gastroenteropathy. Minerva gastroenterologica e dietologica\| PubMed ID: 19829287
Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice. The Journal of physiology\| PubMed ID: 20581042	2010
Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. Gastroenterology\| PubMed ID: 20621681	2010
Generalized neuromuscular hypoplasia, reduced smooth muscle myosin and altered gut motility in the klotho model of premature aging. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 21605285
Epigenetics and chromatin dynamics: a review and a paradigm for functional disorders. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 23095056
Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways. PloS one\| PubMed ID: 24116170
Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal. The Journal of physiology\| PubMed ID: 25063822
Stem cells for murine interstitial cells of cajal suppress cellular immunity and colitis via prostaglandin E2 secretion. Gastroenterology\| PubMed ID: 25637652	2015
FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors. International journal of cancer\| PubMed ID: 25716227	2015
Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. Gastroenterology\| PubMed ID: 25865047
Targeting Disease Persistence in Gastrointestinal Stromal Tumors. Stem cells translational medicine\| PubMed ID: 25934947
Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction. Genome medicine\| PubMed ID: 27716401
Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying. Gastroenterology\| PubMed ID: 28438610
microRNA overexpression in slow transit constipation leads to reduced Na1.5 current and altered smooth muscle contractility. Gut\| PubMed ID: 31757880	2020
Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 32771388
Aging of enteric neuromuscular systems in gastrointestinal tract. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 35279912
A narrative review of imatinib-resistant gastrointestinal stromal tumors. Gastrointestinal stromal tumor\| PubMed ID: 35814621	2021
Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 37301443	2023
The Crucial Role of the Interstitial Cells of Cajal in Neurointestinal Diseases. Biomolecules\| PubMed ID: 37759758	2023
Inhibition of EZH2 Reduces Aging-Related Decline in Interstitial Cells of Cajal of the Mouse Stomach. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 38969206	2024
Protocol for AI-based segmentation and quantification of interstitial cells of Cajal in murine gastric muscle. STAR protocols\| PubMed ID: 39977270	2025
Protocol for AI-supported immunofluorescence colocalization analysis in human enteric neurons. STAR protocols\| PubMed ID: 40382773	2025

Article	Year
Cellular pathogenesis of diabetic gastroenteropathy. Minerva gastroenterologica e dietologica\| PubMed ID: 19829287
Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice. The Journal of physiology\| PubMed ID: 20581042	2010
Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. Gastroenterology\| PubMed ID: 20621681	2010
Generalized neuromuscular hypoplasia, reduced smooth muscle myosin and altered gut motility in the klotho model of premature aging. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 21605285
Epigenetics and chromatin dynamics: a review and a paradigm for functional disorders. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 23095056
Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways. PloS one\| PubMed ID: 24116170
Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal. The Journal of physiology\| PubMed ID: 25063822
Stem cells for murine interstitial cells of cajal suppress cellular immunity and colitis via prostaglandin E2 secretion. Gastroenterology\| PubMed ID: 25637652	2015
FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors. International journal of cancer\| PubMed ID: 25716227	2015
Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. Gastroenterology\| PubMed ID: 25865047
Targeting Disease Persistence in Gastrointestinal Stromal Tumors. Stem cells translational medicine\| PubMed ID: 25934947
Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction. Genome medicine\| PubMed ID: 27716401
Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying. Gastroenterology\| PubMed ID: 28438610
microRNA overexpression in slow transit constipation leads to reduced Na1.5 current and altered smooth muscle contractility. Gut\| PubMed ID: 31757880	2020
Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 32771388
Aging of enteric neuromuscular systems in gastrointestinal tract. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society\| PubMed ID: 35279912
A narrative review of imatinib-resistant gastrointestinal stromal tumors. Gastrointestinal stromal tumor\| PubMed ID: 35814621	2021
Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 37301443	2023
The Crucial Role of the Interstitial Cells of Cajal in Neurointestinal Diseases. Biomolecules\| PubMed ID: 37759758	2023
Inhibition of EZH2 Reduces Aging-Related Decline in Interstitial Cells of Cajal of the Mouse Stomach. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 38969206	2024
Protocol for AI-based segmentation and quantification of interstitial cells of Cajal in murine gastric muscle. STAR protocols\| PubMed ID: 39977270	2025
Protocol for AI-supported immunofluorescence colocalization analysis in human enteric neurons. STAR protocols\| PubMed ID: 40382773	2025