Jianxin Chen

Beijing University of Chinese Medicine

Affiliated withBeijing University of Chinese Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
[Gel electrophoresis analysis on plasma differential protein in patients with unstable angina of blood-stasis pattern]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine\| PubMed ID: 20681277	2010
[Investigative strategy for research on biological basis of traditional Chinese medicine syndrome: feature selection-based data mining methods]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine\| PubMed ID: 20727328	2010
[Edaphic FTIR finger print and the area choice of Chinese herb culture]. Guang pu xue yu guang pu fen xi = Guang pu\| PubMed ID: 20827967	2010
[Analysis of plasma metabonomics of mini-swines with qi deficiency and blood stasis syndrome due to chronic myocardial ischemia]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine\| PubMed ID: 21288451	2011
Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine. Journal of ethnopharmacology\| PubMed ID: 21316437	2011
Discovery of diagnosis pattern of coronary heart disease with qi deficiency syndrome by the T-test-based adaboost algorithm. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 21876710	2011
[Experimental study on metabonomics of coronary heart disease myocardlal ischemia of blood stasis syndrome based on the NOESY pulse NMR]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban\| PubMed ID: 22097206	2011
The effects of jiang-zhi-ning and its main components on cholesterol metabolism. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 22649479	2012
Metabolomics-based study of clinical and animal plasma samples in coronary heart disease with blood stasis syndrome. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 22675387	2012
Study on TCM Syndrome Identification Modes of Coronary Heart Disease Based on Data Mining. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 22675388	2012
The active ingredients of Jiang-Zhi-Ning: study of the Nelumbo nucifera alkaloids and their main bioactive metabolites. Molecules (Basel, Switzerland)\| PubMed ID: 22898740	2012
Clinical data mining of phenotypic network in angina pectoris of coronary heart disease. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 23002393	2012
Energy metabolism disorder and myocardial injury in chronic myocardial ischemia with Qi deficiency and blood stasis syndrome based on 2-DE proteomics. Chinese journal of integrative medicine\| PubMed ID: 23212566	2013
A two-level model for the analysis of syndrome of acute ischemic stroke: from diagnostic model to molecular mechanism. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 23662126	2013
A new comprehensive procedure for the quality control of Semen Cassiae and its application in evaluating commercially available material in China. Chinese journal of natural medicines\| PubMed ID: 23845556	2013
Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases. Journal of ethnopharmacology\| PubMed ID: 23850710	2014
Metabolomic identification of diagnostic plasma biomarkers in humans with chronic heart failure. Molecular bioSystems\| PubMed ID: 23959290	2013
An effective solution to discover synergistic drugs for anti-cerebral ischemia from traditional Chinese medicinal formulae. PloS one\| PubMed ID: 24236065	2013
Effects of traditional Chinese medicine on rats with Type II diabetes induced by high-fat diet and streptozotocin: a urine metabonomic study. African health sciences\| PubMed ID: 24250306	2013
A review of the pharmacological mechanism of traditional Chinese medicine in the intervention of coronary heart disease and stroke. African journal of traditional, complementary, and alternative medicines : AJTCAM\| PubMed ID: 24311882	2013
A New Biomarkers Feature Pattern Consisting of TNF- α , IL-10, and IL-8 for Blood Stasis Syndrome with Myocardial Ischemia. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 24371451	2013
Study on qi deficiency syndrome identification modes of coronary heart disease based on metabolomic biomarkers. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 24795766	2014
Synergism and rules of the new combination drug Yiqijiedu formulae (YQJD) on ischemic stroke based on amino acids (AAs) metabolism. Scientific reports\| PubMed ID: 24889025	2014
Paying attention to the preciseness of conclusion. Annals of the rheumatic diseases\| PubMed ID: 25038235	2014
Phenomics research on coronary heart disease based on human phenotype ontology. BioMed research international\| PubMed ID: 25610858	2014
Large-scale exploration and analysis of drug combinations. Bioinformatics (Oxford, England)\| PubMed ID: 25667546	2015
Matrix Factorization-Based Prediction of Novel Drug Indications by Integrating Genomic Space. Computational and mathematical methods in medicine\| PubMed ID: 26078775	2015
Chinese Herbal Medicine in the Treatment of Chronic Heart Failure: Three-Stage Study Protocol for a Randomized Controlled Trial. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 26089951	2015
Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia. Scientific reports\| PubMed ID: 26537366	2015
Drug-symptom networking: Linking drug-likeness screening to drug discovery. Pharmacological research\| PubMed ID: 26615785	2016
Plasma metabonomics study on toxicity biomarker in rats treated with Euphorbia fischeriana based on LC-MS. Biomedical chromatography : BMC\| PubMed ID: 26856302	2016
Qishen Yiqi Drop Pill improves cardiac function after myocardial ischemia. Scientific reports\| PubMed ID: 27075394	2016
A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging. Scientific reports\| PubMed ID: 27356618	2016
Identification of metabolic biomarkers in patients with type 2 diabetic coronary heart diseases based on metabolomic approach. Scientific reports\| PubMed ID: 27470195	2016
Electroacupuncture Treatment Alleviates Central Poststroke Pain by Inhibiting Brain Neuronal Apoptosis and Aberrant Astrocyte Activation. Neural plasticity\| PubMed ID: 27774321	2016
Systems-biology dissection of mechanisms and chemical basis of herbal formula in treating chronic myocardial ischemia. Pharmacological research\| PubMed ID: 27818233	2016
1-Deoxynojirimycin: Occurrence, Extraction, Chemistry, Oral Pharmacokinetics, Biological Activities and In Silico Target Fishing. Molecules (Basel, Switzerland)\| PubMed ID: 27886092	2016
Transcriptome inference and systems approaches to polypharmacology and drug discovery in herbal medicine. Journal of ethnopharmacology\| PubMed ID: 27894972	2017
Significance of Resveratrol in Clinical Management of Chronic Diseases. Molecules (Basel, Switzerland)\| PubMed ID: 28820474	2017
Metabolic effects of Hedyotis diffusa on rats bearing Walker 256 tumor revealed by NMR-based metabolomics. Magnetic resonance in chemistry : MRC\| PubMed ID: 28847040	2018
FOXO Transcriptional Factors and Long-Term Living. Oxidative medicine and cellular longevity\| PubMed ID: 28894507	2017
H NMR-Based Metabolomics Study of the Toxicological Effects in Rats Induced by "Renqing Mangjue" Pill, a Traditional Tibetan Medicine. Frontiers in pharmacology\| PubMed ID: 28928660	2017
Safety and efficacy of Qishen granules in patients with chronic heart failure: study protocol for a randomized controlled trial. Trials\| PubMed ID: 29017565	2017
System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus. Frontiers in pharmacology\| PubMed ID: 29051733	2017
Mechanism of Chinese Medicine Herbs Effects on Chronic Heart Failure Based on Metabolic Profiling. Frontiers in pharmacology\| PubMed ID: 29213243	2017
Effects of Qijian mixture on type 2 diabetes assessed by metabonomics, gut microbiota and network pharmacology. Pharmacological research\| PubMed ID: 29391233	2018
Heterogeneous network propagation for herb target identification. BMC medical informatics and decision making\| PubMed ID: 29589568	2018
Association between high-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2 and carotid atherosclerosis: A cross-sectional study. Journal of cellular and molecular medicine\| PubMed ID: 30094934	2018
Effects of stress on behavior and resting-state fMRI in rats and evaluation of Telmisartan therapy in a stress-induced depression model. BMC psychiatry\| PubMed ID: 30333002	2018
Heterogeneous network embedding for identifying symptom candidate genes. Journal of the American Medical Informatics Association : JAMIA\| PubMed ID: 30357378	2018
SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping. Nucleic acids research\| PubMed ID: 30380087	2019
Mitochondrial protective effect of neferine through the modulation of nuclear factor erythroid 2-related factor 2 signalling in ischaemic stroke. British journal of pharmacology\| PubMed ID: 30414381	2019
The Effect of Chinese Herbal Medicine on Quality of Life and Exercise Tolerance in Heart Failure With Preserved Ejection Fraction: A Systematic Review and Meta-Analysis of Randomized Control... Frontiers in physiology\| PubMed ID: 30416450	2018
Gender differences in the relationship between alcohol consumption and insomnia in the northern Chinese population. PloS one\| PubMed ID: 30521547	2018
Network pharmacology based investigation of the effects of herbal ingredients on the immune dysfunction in heart disease. Pharmacological research\| PubMed ID: 30579974	2019
Identification of potential plasma biomarkers and metabolic dysfunction for unstable angina pectoris and its complication based on global metabolomics. Bioscience reports\| PubMed ID: 30770400	2019
Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network. Computational and structural biotechnology journal\| PubMed ID: 30867892	2019
Artificial intelligence based discovery of the association between depression and chronic fatigue syndrome. Journal of affective disorders\| PubMed ID: 30877861	2019
Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 30901663	2019
Network pharmacology based investigation into the effect and mechanism of Modified Sijunzi Decoction against the subtypes of chronic atrophic gastritis. Pharmacological research\| PubMed ID: 30991106	2019
Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis. Journal of cellular and molecular medicine\| PubMed ID: 31240862	2019
Effects of Tianshu Capsule on Spontaneously Hypertensive Rats as Revealed by H-NMR-Based Metabolic Profiling. Frontiers in pharmacology\| PubMed ID: 31572179	2019
Metabolomic Profiling of the Synergistic Effects of Ginsenoside Rg1 in Combination with Neural Stem Cell Transplantation in Ischemic Stroke Rats. Journal of proteome research\| PubMed ID: 31968172	2020
Effect of High Calorie Diet on Intestinal Flora in LPS-Induced Pneumonia Rats. Scientific reports\| PubMed ID: 32015367	2020
Toxicological Risks of Renqingchangjue in Rats Evaluated by H NMR-Based Serum and Urine Metabolomics Analysis. ACS omega\| PubMed ID: 32064377	2020
A machine learning-driven study indicates emodin improves cardiac hypertrophy by modulation of mitochondrial SIRT3 signaling. Pharmacological research\| PubMed ID: 32135248	2020
Identification of herbal categories active in pain disorder subtypes by machine learning help reveal novel molecular mechanisms of algesia. Pharmacological research\| PubMed ID: 32278044	2020
Artificial intelligence based identification of the functional role of hirudin in diabetic erectile dysfunction treatment. Pharmacological research\| PubMed ID: 33053440	2021
Deciphering the Pharmacological Mechanisms of Ma Xing Shi Gan Decoction against COVID-19 through Integrating Network Pharmacology and Experimental Exploration. Frontiers in pharmacology\| PubMed ID: 33324213	2020
A network-based machine-learning framework to identify both functional modules and disease genes. Human genetics\| PubMed ID: 33409574	2021
Sodium rutin extends lifespan and health span in mice including positive impacts on liver health. British journal of pharmacology\| PubMed ID: 33555034	2022
Machine learning enables discovery of Gentianine targeting TLR4/NF-κB pathway to repair ischemic stroke injury. Pharmacological research\| PubMed ID: 34563661	2021
Dyspnea Measurement in Acute Heart Failure: A Systematic Review and Evidence Map of Randomized Controlled Trials. Frontiers in medicine\| PubMed ID: 34692723	2021
Constructing tongue coating recognition model using deep transfer learning to assist syndrome diagnosis and its potential in noninvasive ethnopharmacological evaluation. Journal of ethnopharmacology\| PubMed ID: 34896205	2022
TMNP: a transcriptome-based multi-scale network pharmacology platform for herbal medicine. Briefings in bioinformatics\| PubMed ID: 34933331	2022
Artificial Intelligence Uncovers Natural MMP Inhibitor Crocin as a Potential Treatment of Thoracic Aortic Aneurysm and Dissection. Frontiers in cardiovascular medicine\| PubMed ID: 35463768	2022
Tissue metabolomics study to reveal the toxicity of a traditional Tibetan medicine 'Renqing Changjue' in rats. RSC advances\| PubMed ID: 35558588	2018
Editorial: Artificial Intelligence in Traditional Medicine. Frontiers in pharmacology\| PubMed ID: 35991902	2022
Editorial: Network pharmacology and AI. Journal of ethnopharmacology\| PubMed ID: 36773788	2023
Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury increasing the gut microbiota and regulating macrophage anti-inflammatory activity in mice. Acta pharmaceutica Sinica. B\| PubMed ID: 36970196	2023
Erratum: Author correction to 'Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury increasing the gut microbiota and regulating macrophage anti-inflammatory a... Acta pharmaceutica Sinica. B\| PubMed ID: 37655316	2023
Investigation of anti-depression effects and potential mechanisms of the ethyl acetate extract of Rupr. through the integration of experiments, LC-MS/MS chemical analysis, and a systems bi... Frontiers in pharmacology\| PubMed ID: 37954847	2023
Machine learning and experimental screening of chromatin regulator signatures and potential drugs in hepatitis B related hepatocellular carcinoma. Journal of biomolecular structure & dynamics\| PubMed ID: 38111163	2025
MicrobeTCM: A comprehensive platform for the interactions of microbiota and traditional Chinese medicine. Pharmacological research\| PubMed ID: 38272335	2024
HBB contributes to individualized aconitine-induced cardiotoxicity in mice via interfering with ABHD5/AMPK/HDAC4 axis. Acta pharmacologica Sinica\| PubMed ID: 38467717	2024
Multi-omics approaches for the understanding of therapeutic mechanism for Huang-Qi-Long-Dan Granule against ischemic stroke. Pharmacological research\| PubMed ID: 38782148	2024
A genome-scale deep learning model to predict gene expression changes of genetic perturbations from multiplex biological networks. Briefings in bioinformatics\| PubMed ID: 39226889	2024
Mechanism Research of QingReJieDu Formula for Treating Hepatitis B Virus Based on Network Pharmacology. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 39550917	2024
Drug-target interaction prediction by integrating heterogeneous information with mutual attention network. BMC bioinformatics\| PubMed ID: 39563226	2024
NP-TCMtarget: a network pharmacology platform for exploring mechanisms of action of traditional Chinese medicine. Briefings in bioinformatics\| PubMed ID: 40037544	2024
Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 40192737	2025
Machine learning driven prediction of drug efficacy in lung cancer: based on protein biomarkers and clinical features. Life sciences\| PubMed ID: 40355026	2025
TonguExpert: A Deep Learning-Based Algorithm Platform for Fine-Grained Extraction and Classification of Tongue Phenotypes. Phenomics (Cham, Switzerland)\| PubMed ID: 40606562	2025
Nano-Chinese herbal medicines and their delivery strategies for central nervous system disease therapy. Nanoscale horizons\| PubMed ID: 40929099	2025
Salvianolic acid B inhibits melanoma via dual modulation of glycolysis and NK/T cell immunity. International immunopharmacology\| PubMed ID: 40987026	2025
Phlorizin Alleviates Depression-like Behaviors via Gut Microbiota Reprogramming-Induced Methionine to Inhibit Neuroinflammation in Mice Hippocampus. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 41011263	2025
A Hybrid Approach for Exploring Real-World Linear Causality Under Multicollinearity Based on Ischemic Post-Stroke Case Series Treated With Integrated Traditional Chinese and Modern Medicine ... Journal of evidence-based medicine\| PubMed ID: 41077686	2025