Kazuo Yudoh

Department of Frontier Medicine, St. Marianna University School of Medicine

Affiliated withSt. Marianna University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Interleukin-18 enhances monocyte tumor necrosis factor alpha and interleukin-1beta production induced by direct contact with T lymphocytes: implications in rheumatoid arthritis. Arthritis and rheumatism\| PubMed ID: 14872485	2004
Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocy... Arthritis research & therapy\| PubMed ID: 15743486	2005
[Potential involvement of cellular senescence in the pathogenesis of bone and joint disease]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 15799448	2005
Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis. Arthritis research & therapy\| PubMed ID: 15987493	2005
Proteomic surveillance of autoantigens in relapsing polychondritis. Microbiology and immunology\| PubMed ID: 16490929	2006
Fibulin-4 is a target of autoimmunity predominantly in patients with osteoarthritis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16493080	2006
Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the ... Arthritis and rheumatism\| PubMed ID: 16508959	2006
Distinct signaling pathways are involved in hypoxia- and IL-1-induced VEGF expression in human articular chondrocytes. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 16732616	2006
Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach. Arthritis research & therapy\| PubMed ID: 17125526	2006
Crosslinking of the CD69 molecule enhances S100A9 production in activated neutrophils. Microbiology and immunology\| PubMed ID: 17237603	2007
Proteomic surveillance of autoimmunity in Behcet's disease with uveitis: selenium binding protein is a novel autoantigen in Behcet's disease. Experimental eye research\| PubMed ID: 17343851	2007
Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E2 from human articular chondrocytes. BMC musculoskeletal disorders\| PubMed ID: 17374154	2007
Comprehensive investigation of disease-specific short peptides in sera from patients with systemic sclerosis: complement C3f-des-arginine, detected predominantly in systemic sclerosis sera, ... Arthritis and rheumatism\| PubMed ID: 17530642	2007
Water-soluble C60 fullerene prevents degeneration of articular cartilage in osteoarthritis via down-regulation of chondrocyte catabolic activity and inhibition of cartilage degeneration duri... Arthritis and rheumatism\| PubMed ID: 17907184	2007
Involvement of post-translational modification of neuronal plasticity-related proteins in hyperalgesia revealed by a proteomic analysis. Proteomics\| PubMed ID: 18340631	2008
Proteomic surveillance of retinal autoantigens in endogenous uveitis: implication of esterase D and brain-type creatine kinase as novel autoantigens. Molecular vision\| PubMed ID: 18552983	2008
Water-soluble fullerene (C60) inhibits the development of arthritis in the rat model of arthritis. International journal of nanomedicine\| PubMed ID: 19918368	2009
Water-soluble fullerene (C60) inhibits the osteoclast differentiation and bone destruction in arthritis. International journal of nanomedicine\| PubMed ID: 19918370	2009
Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor. BMC research notes\| PubMed ID: 20205862	2010
Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity. International journal of general medicine\| PubMed ID: 20360891	2009
Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing. International journal of rheumatic diseases\| PubMed ID: 20374325	2009
Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysis. Arthritis research & therapy\| PubMed ID: 20527084	2009
[Detection of specific markers: our research on the marker in patients with Kawasaki disease]. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology\| PubMed ID: 20818149	2010
Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes. Annals of the rheumatic diseases\| PubMed ID: 20870807	2011
Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA). Aging\| PubMed ID: 21098883	2010
Anti-endothelial cell antibodies (AECA) in patients with systemic vasculitis: our research using proteomics. Expert opinion on biological therapy\| PubMed ID: 21133816	2011
Overexpression of SPACIA1/SAAL1, a newly identified gene that is involved in synoviocyte proliferation, accelerates the progression of synovitis in mice and humans. Arthritis and rheumatism\| PubMed ID: 22127701	2011
Layilin, a talin-binding hyaluronan receptor, is expressed in human articular chondrocytes and synoviocytes and is down-regulated by interleukin-1β. Modern rheumatology\| PubMed ID: 22722918	2013
Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis. International journal of rheumatic diseases\| PubMed ID: 22898216	2012
Expression of Angiotensin II Receptor-1 in Human Articular Chondrocytes. Arthritis\| PubMed ID: 23346400	2012
Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy. Brain : a journal of neurology\| PubMed ID: 23892452	2013
Serum level of soluble triggering receptor expressed on myeloid cells-1 as a biomarker of disease activity in relapsing polychondritis. Modern rheumatology\| PubMed ID: 24261769	2014
Secretion of inflammatory factors from chondrocytes by layilin signaling. Biochemical and biophysical research communications\| PubMed ID: 25150153	2014
The DNA repair enzyme apurinic/apyrimidinic endonuclease (Apex nuclease) 2 has the potential to protect against down-regulation of chondrocyte activity in osteoarthritis. International journal of molecular sciences\| PubMed ID: 25158232	2014
Age-related Decrease of Sirtuin 2 Protein in Human Peripheral Blood Mononuclear Cells. Current aging science\| PubMed ID: 25643068	2015
Cardiac involvement in relapsing polychondritis in Japan. Rheumatology (Oxford, England)\| PubMed ID: 26361883	2016
Cutaneous manifestations of patients with relapsing polychondritis: an association with extracutaneous complications. Clinical rheumatology\| PubMed ID: 26780448	2016
The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinas... International journal of molecular sciences\| PubMed ID: 27367673	2016
Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting : Toronto, Canada. 14-17 April 2016. Pediatric rheumatology online journal\| PubMed ID: 27409414	2016
A suppressive effect of prostaglandin E on the expression of /plasminogen activator inhibitor-1 in human articular chondrocytes: An pilot study. Open access rheumatology : research and reviews\| PubMed ID: 27789978	2009
Organ involvement pattern suggests subgroups within relapsing polychondritis: comment on the article by Dion et al. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 28941194	2018
T cells upon activation promote endothelin 1 production in monocytes via IFN-γ and TNF-α. Scientific reports\| PubMed ID: 29101349	2017
Multiple target autoantigens on endothelial cells identified in juvenile dermatomyositis using proteomics. Rheumatology (Oxford, England)\| PubMed ID: 29361142	2018
SPACIA1/SAAL1 Deletion Results in a Moderate Delay in Collagen-Induced Arthritis Activity, along with mRNA Decay of Gene. International journal of molecular sciences\| PubMed ID: 30513680	2018
A novel, self-assembled artificial cartilage-hydroxyapatite conjugate for combined articular cartilage and subchondral bone repair: histopathological analysis of cartilage tissue engineering... International journal of nanomedicine\| PubMed ID: 30863061	2019
Effects of Different Exercise Conditions on Antioxidant Potential and Mental Assessment. Sports (Basel, Switzerland)\| PubMed ID: 33802504	2021
Physiologic Mechanical Stress Directly Induces Bone Formation by Activating Glucose Transporter 1 (Glut 1) in Osteoblasts, Inducing Signaling via NAD+-Dependent Deacetylase (Sirtuin 1) and R... International journal of molecular sciences\| PubMed ID: 34445787	2021
Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis. Rheumatology (Oxford, England)\| PubMed ID: 34791087	2022
Association of anti-TPM4 autoantibodies with vasculopathic cutaneous manifestations in juvenile dermatomyositis. Rheumatology (Oxford, England)\| PubMed ID: 37144941	2023
Bone Development and Regeneration 2.0. International journal of molecular sciences\| PubMed ID: 37240107	2023
Streptococcal infection and autoimmune diseases. Frontiers in immunology\| PubMed ID: 38464518	2024
Nicotinamide Adenine Dinucleotide (NAD)-Dependent Protein Deacetylase, Sirtuin, as a Biomarker of Healthy Life Expectancy: A Mini- Review. Current aging science\| PubMed ID: 39377386	2025
Pain Candidate Genes 5-HTTLPR and COMT Affect Anxiety and Mood in Japanese Ballet Dancers: A Cross-Sectional and Longitudinal Study. Sports (Basel, Switzerland)\| PubMed ID: 39590895	2024
CDK6-Dependent, CDK4-Independent Synovial Hyperplasia in Arthritic Mice and Tumor Necrosis Factor-α-Induced Proliferation of Synovial Fibroblasts. International journal of molecular sciences\| PubMed ID: 39940918	2025
Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 ... International journal of molecular sciences\| PubMed ID: 40507779	2025