ganzhirong-granule-inhibits-hepatic-gluconeogenesis-through-sirt3

Ganzhirong Granule Inhibits Hepatic Gluconeogenesis through the SIRT3-MPC1-PC/PDH Axis in Type 2 Diabetes

Type 2 diabetes mellitus (T2DM) is a global metabolic disorder characterized by hepatic insulin resistance and excessive gluconeogenesis. Ganzhirong ...

Changchun University of Chinese Medicine

the Affiliated Hospital to Changchun University of Chinese Medicine

Previous observational studies have demonstrated a link between diabetes mellitus(DM) and primary biliary cholangitis (PBC). Nevertheless, since these relationships might be confused, whether there is any causal connection or in which direction it exists is unclear. Our investigation aimed to identify the causal associations between DM and PBC.

Association between diabetes mellitus and primary biliary cholangitis: a two-sample Mendelian randomization study.

Although many researches have shown a relationship between sleeping habits and the risk of developing colorectal cancer (CRC), there is a lack of data from randomized controlled trials (RCTs) to support this point. Hence, this study used Mendelian randomization (MR) to robustly assess whether five primary sleep characteristics are directly linked with the risk of CRC occurrence.

Article	Year
Association between diabetes mellitus and primary biliary cholangitis: a two-sample Mendelian randomization study. Frontiers in endocrinology\| PubMed ID: 38774228	2024
Associations between sleep traits and colorectal cancer: a mendelian randomization analysis. Frontiers in oncology\| PubMed ID: 39980544	2025

Dan Lv

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