Enrique Leira

Departments of Neurology & Neurosurgery, University of Iowa

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Tips for a Successful Scientific Presentation. Stroke\| PubMed ID: 31272322	2019
Can we predict early recurrence in acute stroke? Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 15218280	2004
Blood pressure surge precedes intracerebral hemorrhage. Neurocritical care\| PubMed ID: 16174967	2005
Feasibility of acute clinical trials during aerial interhospital transfer. Stroke\| PubMed ID: 16946166	2006
Slow progressive acceptance of intravenous thrombolysis for patients with stroke by rural primary care physicians. Archives of neurology\| PubMed ID: 17420312	2007
Improving prediction of outcome in "good grade" subarachnoid hemorrhage. Neurosurgery\| PubMed ID: 17881957	2007
Rural-urban differences in acute stroke management practices: a modifiable disparity. Archives of neurology\| PubMed ID: 18625855	2008
Treating patients with 'wake-up' stroke: the experience of the AbESTT-II trial. Stroke\| PubMed ID: 18772451	2008
Baseline NIH stroke scale responses estimate the probability of each particular stroke subtype. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 18946211	2008
Strategies to improve acute stroke care of patients in rural and other geographically dispersed areas. Current treatment options in neurology\| PubMed ID: 18990313	2008
Development of an emergency department response to acute stroke ("Code Stroke"). Current neurology and neuroscience reports\| PubMed ID: 19080751	2009
Extending acute trials to remote populations: a pilot study during interhospital helicopter transfer. Stroke\| PubMed ID: 19131655	2009
Toward fully automated processing of dynamic susceptibility contrast perfusion MRI for acute ischemic cerebral stroke. Computer methods and programs in biomedicine\| PubMed ID: 20060614	2010
Lack of international consensus on ethical aspects of acute stroke trials. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 20719537	2012
Previous statin use is not associated with an increased prevalence or degree of gradient-echo lesions in patients with acute ischemic stroke or transient ischemic attack. Stroke\| PubMed ID: 21164134	2011
Effect of antidepressants on the course of disability following stroke. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry\| PubMed ID: 21358384	2011
The types of neurological deficits might not justify withholding treatment in patients with low total National Institutes of Health Stroke Scale scores. Stroke\| PubMed ID: 22308246	2012
Primary stroke centers should be located using maximal coverage models for optimal access. Stroke\| PubMed ID: 22811453	2012
The growing shortage of vascular neurologists in the era of health reform: planning is brain! Stroke\| PubMed ID: 23386675	2013
The NIHSS supplementary motor scale: a valid tool for multidisciplinary recovery trials. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 23921195	2013
Residency training: a failed lumbar puncture is more about obesity than lack of ability. Neurology\| PubMed ID: 25754807	2015
Effect of helicopter transport on neurological outcomes in a mouse model of embolic stroke with reperfusion: AIR-MICE pilot study. International journal of stroke : official journal of the International Stroke Society\| PubMed ID: 26376603	2015
Time to treat stroke patients in rural locations as an underserved minority. Neurology\| PubMed ID: 28053007	2017
Uric acid therapy improves the outcomes of stroke patients treated with intravenous tissue plasminogen activator and mechanical thrombectomy. International journal of stroke : official journal of the International Stroke Society\| PubMed ID: 28345429	2017
Brain Multimodality Monitoring: A New Tool in Neurocritical Care of Comatose Patients. Critical care research and practice\| PubMed ID: 28555164	2017
Complete reperfusion is required for maximal benefits of mechanical thrombectomy in stroke patients. Scientific reports\| PubMed ID: 28912596	2017
Dual antiplatelet therapy in aneurysmal subarachnoid hemorrhage: association with reduced risk of clinical vasospasm and delayed cerebral ischemia. Journal of neurosurgery\| PubMed ID: 29099296	2018
Measurement of Elevated IL-37 Levels in Acute Ischemic Brain Injury: A Cross-sectional Pilot Study. Cureus\| PubMed ID: 29234571	2017
Chart validation of inpatient ICD-9-CM administrative diagnosis codes for ischemic stroke among IGIV users in the Sentinel Distributed Database. Medicine\| PubMed ID: 29384925	2017
Treatment with Uric Acid Reduces Infarct and Improves Neurologic Function in Female Mice After Transient Cerebral Ischemia. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 29398531	2018
Cerebral Microbleeds are an Independent Predictor of Hemorrhagic Transformation Following Intravenous Alteplase Administration in Acute Ischemic Stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 29398533	2018
Spinal Cord Infarction Presenting as a Hemicord Syndrome: Report of 2 Cases. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 29422381	2018
Polygenic Risk for Depression Increases Risk of Ischemic Stroke: From the Stroke Genetics Network Study. Stroke\| PubMed ID: 29438084	2018
Distance from Home to Research Center: A Barrier to In-Person Visits but Not Treatment Adherence in a Stroke Trial. Neuroepidemiology\| PubMed ID: 29587267	2018
Development of a cerebral mycotic aneurysm within 5 days. Neurology. Clinical practice\| PubMed ID: 29620063	2017
Impact of Stroke Call on the Stroke Neurology Workforce in the United States: Possible Challenges and Opportunities. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 29625799	2018
Intraventricular extension of an aneurysmal subarachnoid hemorrhage is an independent predictor of a worse functional outcome. Clinical neurology and neurosurgery\| PubMed ID: 29730271	2018
In the Era of Thrombectomy, Let Us Also Protect the Majority of Patients With Stroke Who Only Require Medical Treatment! Stroke\| PubMed ID: 29748421	2018
Helicopter "Drip and Ship" Flights Do Not Alter the Pharmacological Integrity of rtPA. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 30037651	2018
Emergent Uric Acid Treatment is Synergistic with Mechanical Recanalization in Improving Stroke Outcomes in Male and Female Rats. Neuroscience\| PubMed ID: 30077000	2018
Interhospital Transfer Delays Anticoagulation Reversal in Warfarin-Associated Intracranial Hemorrhage. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 30172677	2018
Comparison of Cardiovascular Risk Factors for Coronary Heart Disease and Stroke Type in Women. Journal of the American Heart Association\| PubMed ID: 30371339	2018
Disparities in Inter-hospital Helicopter Transportation for Hispanics by Geographic Region: A Threat to Fairness in the Era of Thrombectomy. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 30552028	2019
Secular Increases in Spontaneous Subarachnoid Hemorrhage during Pregnancy: A Nationwide Sample Analysis. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 30711414	2019
Neurological Complications of Cardiological Interventions. Current neurology and neuroscience reports\| PubMed ID: 30739219	2019
Corrigendum to Intracerebral Hemorrhage in Multiple Sclerosis: A Retrospective Cohort Study [Journal of Stroke and Cerebrovascular Diseases Volume 28, Issue 2, February 2019, Pages 267-275]. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 30745231	2019
Helicopter transportation in the era of thrombectomy: The next frontier for acute stroke treatment and research. European stroke journal\| PubMed ID: 31008278	2016
EXTEND Trial. Stroke\| PubMed ID: 31449480	2019
Computed Tomography Angiogram Derived From Computed Tomography Perfusion Done with Low Iodine Volume Protocol Preserves Diagnostic Yield for Middle Cerebral Artery-M2 Occlusions. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 31662241	2019
Remote Ischemic Conditioning: Increasing the Pressure for Rigorous Efficacy Trials. Journal of the American Heart Association\| PubMed ID: 31747865	2019
Neurological Complications in Patients with Systemic Lupus Erythematosus. Current neurology and neuroscience reports\| PubMed ID: 31773306	2019
The Chemical Optimization of Cerebral Embolectomy trial: Study protocol. International journal of stroke : official journal of the International Stroke Society\| PubMed ID: 31852410	2021
Characteristics and outcomes in patients with atrial fibrillation receiving direct oral anticoagulants in off-label doses. BMC cardiovascular disorders\| PubMed ID: 32013886	2020
Stroke mechanisms and outcomes of isolated symptomatic basilar artery stenosis. Stroke and vascular neurology\| PubMed ID: 32030202	2019
Preserving stroke care during the COVID-19 pandemic: Potential issues and solutions. Neurology\| PubMed ID: 32385186	2020
Low-Frequency Vibrations Enhance Thrombolytic Therapy and Improve Stroke Outcomes. Stroke\| PubMed ID: 32397935	2020
Approaches to global stroke care during the COVID-19 pandemic. Stroke and vascular neurology\| PubMed ID: 32447298	2020
Cytokine Registry In Stroke Patients (CRISP): Protocol of a prospective observational study. Medicine\| PubMed ID: 32664088	2020
Subtle ocular movements in a patient with brain death. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 32807410	2020
Differential Risk Factors and Outcomes of Ischemic Stroke due to Cervical Artery Dissection in Young Adults. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 32980848	2020
Secular Trends for Etiologies of Acute Ischemic Stroke in Young Adults. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 32992166	2020
Detection and Quantification of Symptomatic Atherosclerotic Plaques With High-Resolution Imaging in Cryptogenic Stroke. Stroke\| PubMed ID: 32998652	2020
Management of Ischemic Stroke Following Left Ventricular Assist Device. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 33254382	2020
Risk of Ischemic Stroke after an Inpatient Hospitalization for Transient Ischemic Attack in the United States. Neuroepidemiology\| PubMed ID: 33260176	2021
Outcomes of interfacility helicopter transportation in acute stroke care. Neurology. Clinical practice\| PubMed ID: 33299670	2020
Comparative Effectiveness and Safety of Direct Oral Anticoagulants in Obese Patients with Atrial Fibrillation. Cardiovascular drugs and therapy\| PubMed ID: 33404923	2021
Impact of Intracerebral Hematoma Evacuation During Decompressive Hemicraniectomy on Functional Outcomes. Stroke\| PubMed ID: 33504184	2021
Neurologic complications of heart surgery. Handbook of clinical neurology\| PubMed ID: 33632458	2021
Transient global amnesia does not increase the risk of subsequent ischemic stroke: a propensity score-matched analysis. Journal of neurology\| PubMed ID: 33651152	2021
Effects of the Menstrual Cycle on Neurological Disorders. Current neurology and neuroscience reports\| PubMed ID: 33970361	2021
The Intracerebral Hemorrhage Score Overestimates Mortality in Young Adults. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 34247055	2021
Risk of Venous Thromboembolism in Hospitalized Patients with Acute Ischemic Stroke Versus Other Neurological Conditions. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 34500199	2021
Cytokines, brain proteins, and growth factors in acute stroke patients: A pilot study. Surgical neurology international\| PubMed ID: 34513133	2021
PKM2 promotes neutrophil activation and cerebral thromboinflammation: therapeutic implications for ischemic stroke. Blood\| PubMed ID: 34529778	2022
Self-controlled assessment of thromboembolic event (TEE) risk following intravenous immune globulin (IGIV) in the U.S. (2006-2012). Journal of thrombosis and thrombolysis\| PubMed ID: 34817789	2022
Dedicated Guidelines for Arterial Dissections: More Specifics Amid Uncertainty. Stroke\| PubMed ID: 34937422	2022
The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results. Stroke\| PubMed ID: 35354299	2022
In-Hospital Outcomes and Recurrence of Acute Ischemic Stroke in Patients With Solid Organ Malignancy. Neurology\| PubMed ID: 35487697	2022
Ambient Pollution and Stroke: Time to Clear the Air on Causal Mechanisms. Neurology\| PubMed ID: 35613932	2022
In-hospital outcomes and recurrence of stroke during pregnancy and puerperium. International journal of stroke : official journal of the International Stroke Society\| PubMed ID: 35838335	2023
High resolution 7T MR imaging in characterizing culprit intracranial atherosclerotic plaques. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences\| PubMed ID: 36573263	2025
Targeting Neutrophil α9 Improves Functional Outcomes After Stroke in Mice With Obesity-Induced Hyperglycemia. Stroke\| PubMed ID: 37449422	2023
A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke. Science translational medicine\| PubMed ID: 37729432	2023
Uric Acid: A Translational Journey in Cerebroprotection That Spanned Preclinical and Human Data. Neurology\| PubMed ID: 37848338	2023
Intravenous Thrombolysis for Acute Ischemic Stroke in Patients With Recent Direct Oral Anticoagulant Use: A Systematic Review and Meta-Analysis. Journal of the American Heart Association\| PubMed ID: 38108256	2023
Transcarotid Arterial Revascularization of Symptomatic Internal Carotid Artery Disease: A Systematic Review and Study-Level Meta-Analysis. Stroke\| PubMed ID: 38299350	2024
Rationale and Design of the Statin Use in Intracerebral Hemorrhage Patients (SATURN) Trial. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 38493765	2025
The Role of the Vascular Neurologist in Optimizing Stroke Care. Neurologic clinics\| PubMed ID: 38937039	2024
Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial. Circulation research\| PubMed ID: 39034919	2024
Endovascular Thrombectomy for Extracranial Internal Carotid Artery Occlusions With Large Ischemic Strokes: Insights From the SELECT2 Trial. Neurology\| PubMed ID: 39869840	2025
Uric Acid Stroke Cerebroprotection Transcended Sex, Age, and Comorbidities in a Multicenter Preclinical Trial. Stroke\| PubMed ID: 40091742	2025
Prioritizing gaps in stroke care: A two-round Delphi process. European stroke journal\| PubMed ID: 40178329	2025
Determinants of Outcome After Endovascular Middle Cerebral Artery Occlusion in Rats in the SPAN Trial. Stroke\| PubMed ID: 40396268	2025
Multicenter SPAN Trial of Fasudil in Ischemic Stroke. Stroke\| PubMed ID: 40421536	2025
Fingolimod as a Potential Cerebroprotectant Results From the Stroke Preclinical Assessment Network. Stroke\| PubMed ID: 40899256	2025
Multicenter Stroke Preclinical Assessment Network Analysis of Cardiovascular Risk Factor Subgroups Treated With the Poly(ADP-Ribose) Polymerase Inhibitor Veliparib. Journal of the American Heart Association\| PubMed ID: 40996065	2025
Chemical Optimization of Cerebral Embolectomy 2 (CHOICE 2) trial: study protocol. Stroke and vascular neurology\| PubMed ID: 41339082	2025
Evaluating tocilizumab in ischemic stroke: Findings from the SPAN multicenter trial. Neuropharmacology\| PubMed ID: 41354124	2025