Cenk Ayata

Neurovascular Research Unit, Mass General Brigham

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9050895	1997
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 9278526	1997
Intensive care management of specific stroke treatment. Advances in neurology\| PubMed ID: 12760202	2003
Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15241182	2004
Achieving normothermia in patients with febrile subarachnoid hemorrhage: feasibility and safety of a novel intravascular cooling catheter. Neurocritical care\| PubMed ID: 16174910	2004
Cortical spreading depression confounds concentration-dependent pial arteriolar dilation during N-methyl-D-aspartate superfusion. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16299263	2006
Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 16340958	2006
Suppression of cortical spreading depression in migraine prophylaxis. Annals of neurology\| PubMed ID: 16450381	2006
Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 17033691	2007
Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia. Brain : a journal of neurology\| PubMed ID: 17468117	2007
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. The Journal of clinical investigation\| PubMed ID: 17557122	2007
Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain : a journal of neurology\| PubMed ID: 17638859	2007
A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System. Stroke\| PubMed ID: 17901381	2007
Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia. Neuroscience\| PubMed ID: 17936515	2007
Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia. Stroke; a journal of cerebral circulation\| PubMed ID: 18340095	2008
Linking Notch signaling to ischemic stroke. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18347334	2008
Hypoxia and hypotension transform the blood flow response to cortical spreading depression from hyperemia into hypoperfusion in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 18446167	2008
The impact of anesthetics and hyperoxia on cortical spreading depression. Experimental neurology\| PubMed ID: 18501348	2008
Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia. Journal of biomedical optics\| PubMed ID: 19021335	2008
Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1. The Journal of clinical investigation\| PubMed ID: 19104150	2009
Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression. Applied optics\| PubMed ID: 19340106	2009
Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice. Annals of neurology\| PubMed ID: 19847904	2009
Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 20087371	2010
Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis. Nature biotechnology\| PubMed ID: 20160716	2010
Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Annals of neurology\| PubMed ID: 20225282	2010
Cortical spreading depression and migraine. Current neurology and neuroscience reports\| PubMed ID: 20425031	2010
Cortical spreading depression triggers migraine attack: pro. Headache\| PubMed ID: 20456160	2010
Gabapentin suppresses cortical spreading depression susceptibility. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 20588320	2010
Soluble guanylate cyclase alpha1beta1 limits stroke size and attenuates neurological injury. Stroke; a journal of cerebral circulation\| PubMed ID: 20595671	2010
CADASIL: experimental insights from animal models. Stroke\| PubMed ID: 20876488	2010
Oxcarbazepine does not suppress cortical spreading depression. Cephalalgia : an international journal of headache\| PubMed ID: 21059627	2011
Optical coherence tomography for the quantitative study of cerebrovascular physiology. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 21364599	2011
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression. Annals of neurology\| PubMed ID: 21387384	2011
Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21490217	2011
Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 21505480	2011
Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21555590	2011
Cortical spreading depression impairs oxygen delivery and metabolism in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 22008729	2012
Two-photon microscopy of cortical NADH fluorescence intensity changes: correcting contamination from the hemodynamic response. Journal of biomedical optics\| PubMed ID: 22029350	2011
Cerebrovascular lesions induce transient β-amyloid deposition. Brain : a journal of neurology\| PubMed ID: 22120142	2011
Genetic animal models of cerebral vasculopathies. Progress in molecular biology and translational science\| PubMed ID: 22137428	2012
Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations. Circulation\| PubMed ID: 22144569	2012
Pharmacological targeting of spreading depression in migraine. Expert review of neurotherapeutics\| PubMed ID: 22364328	2012
Glucose modulation of spreading depression susceptibility. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 22968322	2013
Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury. Experimental neurology\| PubMed ID: 22981452	2012
Concussive injury before or after controlled cortical impact exacerbates histopathology and functional outcome in a mixed traumatic brain injury model in mice. Journal of neurotrauma\| PubMed ID: 23153355	2013
Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury. The Journal of clinical investigation\| PubMed ID: 23281396	2013
Quantitative imaging of cerebral blood flow velocity and intracellular motility using dynamic light scattering-optical coherence tomography. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 23403378	2013
Hyperlipidemia disrupts cerebrovascular reflexes and worsens ischemic perfusion defect. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 23486293	2013
Calabadion: A new agent to reverse the effects of benzylisoquinoline and steroidal neuromuscular-blocking agents. Anesthesiology\| PubMed ID: 23549405	2013
Subarachnoid hemorrhage, spreading depolarizations and impaired neurovascular coupling. Stroke research and treatment\| PubMed ID: 23577279	2013
Pearls and pitfalls in experimental models of spreading depression. Cephalalgia : an international journal of headache\| PubMed ID: 23671256	2013
Spreading depression and neurovascular coupling. Stroke\| PubMed ID: 23709742	2013
Age-related decline in oligodendrogenesis retards white matter repair in mice. Stroke\| PubMed ID: 23881957	2013
Multiparametric, longitudinal optical coherence tomography imaging reveals acute injury and chronic recovery in experimental ischemic stroke. PloS one\| PubMed ID: 23940761	2013
Rho-kinase inhibition improves ischemic perfusion deficit in hyperlipidemic mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 24192634	2014
First-order mathematical modeling of brain swelling in focal cerebral ischemia. Translational stroke research\| PubMed ID: 24323451	2010
Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines. Stroke; a journal of cerebral circulation\| PubMed ID: 24407954	2014
Selective ROCK2 Inhibition In Focal Cerebral Ischemia. Annals of clinical and translational neurology\| PubMed ID: 24466563	2014
Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage. Brain research\| PubMed ID: 24502984	2014
Recognition memory impairments after subcortical white matter stroke in mice. Stroke\| PubMed ID: 24723319	2014
Migraine and stroke: in search of shared mechanisms. Cephalalgia : an international journal of headache\| PubMed ID: 25228681	2015
Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25349415	2014
Endothelial dysfunction abrogates the efficacy of normobaric hyperoxia in stroke. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25392489	2014
Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice. Stroke\| PubMed ID: 25424478	2015
Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nature communications\| PubMed ID: 25483924	2014
Migraine pathophysiology: lessons from mouse models and human genetics. The Lancet. Neurology\| PubMed ID: 25496898	2015
Etomidate and Ketamine: Residual Motor and Adrenal Dysfunction that Persist beyond Recovery from Loss of Righting Reflex in Rats. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 25551398	2014
The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia. PloS one\| PubMed ID: 25608039	2015
Lasting pure-motor deficits after focal posterior internal capsule white-matter infarcts in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25649992	2015
Sustained functional improvement by hepatocyte growth factor-like small molecule BB3 after focal cerebral ischemia in rats and mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25712497	2015
Migraine mutations impair hippocampal learning despite enhanced long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25716839	2015
Supply-demand mismatch transients in susceptible peri-infarct hot zones explain the origins of spreading injury depolarizations. Neuron\| PubMed ID: 25741731	2015
Late-onset thermal hypersensitivity after focal ischemic thalamic infarcts as a model for central post-stroke pain in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25899295	2015
High-resolution in vivo optical imaging of stroke injury and repair. Brain research\| PubMed ID: 25960347	2015
Imaging PEG-like nanoprobes in tumor, transient ischemia, and inflammatory disease models. Bioconjugate chemistry\| PubMed ID: 25971846	2015
Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice. Annals of neurology\| PubMed ID: 26032020	2015
Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature. Physiological reviews\| PubMed ID: 26133935	2015
Decreased microvascular cerebral blood flow assessed by diffuse correlation spectroscopy after repetitive concussions in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 26154866	2015
Micro-heterogeneity of flow in a mouse model of chronic cerebral hypoperfusion revealed by longitudinal Doppler optical coherence tomography and angiography. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 26243708	2015
Multifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury? Glia\| PubMed ID: 26301517	2016
Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents. Anesthesiology\| PubMed ID: 26418697	2015
Sensitivity to acute cerebral ischemic injury in migraineurs: A retrospective case-control study. Neurology\| PubMed ID: 26537055	2015
VAGUS NERVE STIMULATION INHIBITS CORTICAL SPREADING DEPRESSION. Pain\| PubMed ID: 26645547	2015
High-flow oxygen therapy for treatment of acute migraine: A randomized crossover trial. Cephalalgia : an international journal of headache\| PubMed ID: 27206964	2017
Spreading Depression in Primary and Secondary Headache Disorders. Current pain and headache reports\| PubMed ID: 27215627	2016
Spreading Depolarizations: A Therapeutic Target Against Delayed Cerebral Ischemia After Subarachnoid Hemorrhage. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society\| PubMed ID: 27258442	2016
Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines. Translational stroke research\| PubMed ID: 27297402	2016
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 27317657	2016
The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 27328690	2017
Requisite ischemia for spreading depolarization occurrence after subarachnoid hemorrhage in rodents. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 27432225	2017
Anesthesia in Experimental Stroke Research. Translational stroke research\| PubMed ID: 27534542	2016
Migraine: Treasure hunt in a minefield - exploring migraine with GWAS. Nature reviews. Neurology\| PubMed ID: 27539559	2016
Translational MR Neuroimaging of Stroke and Recovery. Translational stroke research\| PubMed ID: 27578048	2017
Challenges and Controversies in Translational Stroke Research - an Introduction. Translational stroke research\| PubMed ID: 27581304	2016
Early Activation of Phosphatidylinositol 3-Kinase after Ischemic Stroke Reduces Infarct Volume and Improves Long-Term Behavior. Molecular neurobiology\| PubMed ID: 27590139	2017
Fleeting footprints: finding MRI biomarkers of transient ischaemic attack. Brain : a journal of neurology\| PubMed ID: 28031217	2017
Endovascular thrombectomy and post-procedural headache. The journal of headache and pain\| PubMed ID: 28130625	2017
Emerging concepts in sporadic cerebral amyloid angiopathy. Brain : a journal of neurology\| PubMed ID: 28334869	2017
Inhibition of the P2X7-PANX1 complex suppresses spreading depolarization and neuroinflammation. Brain : a journal of neurology\| PubMed ID: 28430869	2017
Translational Stroke Research: Vision and Opportunities. Stroke\| PubMed ID: 28751554	2017
Novel Therapeutic Targets Against Spreading Depression. Headache\| PubMed ID: 28842982	2017
Aspirin Prophylaxis for Migraine with Aura: An Observational Case Series. European neurology\| PubMed ID: 29017164	2017
Posterior reversible encephalopathy syndrome in stroke-prone spontaneously hypertensive rats on high-salt diet. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 29350576	2019
Determinants of Optogenetic Cortical Spreading Depolarizations. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 29425263	2019
Intrinsic optical signal imaging of the blood volume changes is sufficient for mapping the resting state functional connectivity in the rodent cortex. Journal of neural engineering\| PubMed ID: 29451130	2018
An Overhauser-enhanced-MRI platform for dynamic free radical imaging in vivo. NMR in biomedicine\| PubMed ID: 29493032	2018
The Role of Endothelin in the Pathophysiology of Migraine-a Systematic Review. Current pain and headache reports\| PubMed ID: 29557064	2018
Caffeine does not affect susceptibility to cortical spreading depolarization in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 29651899	2019
Continuous electroencephalography predicts delayed cerebral ischemia after subarachnoid hemorrhage: A prospective study of diagnostic accuracy. Annals of neurology\| PubMed ID: 29659050	2018
Enriched Environment Elicits Proangiogenic Mechanisms After Focal Cerebral Ischemia. Translational stroke research\| PubMed ID: 29700717	2019
Different Effects of Normobaric Oxygen in Normotensive Versus Hypertensive Rats After Focal Cerebral Ischemia. Stroke\| PubMed ID: 29712880	2018
Rho-kinase inhibitors do not expand hematoma volume in acute experimental intracerebral hemorrhage. Annals of clinical and translational neurology\| PubMed ID: 29928660	2018
Monitoring anoxic depolarization at the bedside: A step closer to the 24th century. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 29961421	2018
Cortical Spreading Depression Denotes Concussion Injury. Journal of neurotrauma\| PubMed ID: 29999455	2019
Spreading depolarizations trigger caveolin-1-dependent endothelial transcytosis. Annals of neurology\| PubMed ID: 30014540	2018
Real-time non-invasive in vivo visible light detection of cortical spreading depolarizations in mice. Journal of neuroscience methods\| PubMed ID: 30194041	2018
Cognitive dysfunction and migraine. The journal of headache and pain\| PubMed ID: 30442090	2018
Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: Experimental-Clinical Disconnect and the Unmet Need. Neurocritical care\| PubMed ID: 30671784	2020
Neurovascular origin of primary headaches. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 30929598	2019
Noninvasive Vagus Nerve Stimulation Prevents Ruptures and Improves Outcomes in a Model of Intracranial Aneurysm in Mice. Stroke\| PubMed ID: 30943885	2019
Secondary Bleeding During Acute Experimental Intracerebral Hemorrhage. Stroke\| PubMed ID: 31009358	2019
Neurovascular coupling during optogenetic functional activation: Local and remote stimulus-response characteristics, and uncoupling by spreading depression. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 31063009	2020
Differential effects of anesthetics on resting state functional connectivity in the mouse. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 31092086	2020
Pathophysiology of Lacunar Stroke: History's Mysteries and Modern Interpretations. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 31151839	2019
Non-invasively triggered spreading depolarizations induce a rapid pro-inflammatory response in cerebral cortex. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 31242047	2020
Relief Following Chronic Stress Augments Spreading Depolarization Susceptibility in Familial Hemiplegic Migraine Mice. Neuroscience\| PubMed ID: 31299346	2019
What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient? Neurocritical care\| PubMed ID: 31338747	2020
Which Spreading Depolarizations Are Deleterious To Brain Tissue? Neurocritical care\| PubMed ID: 31388871	2020
cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 31423931	2019
Cerebrovascular effects of endothelin-1 investigated using high-resolution magnetic resonance imaging in healthy volunteers. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 31500524	2020
Headache after ischemic stroke: A systematic review and meta-analysis. Neurology\| PubMed ID: 31694924	2020
Mapping optogenetically-driven single-vessel fMRI with concurrent neuronal calcium recordings in the rat hippocampus. Nature communications\| PubMed ID: 31748553	2019
Intravenous Endothelin-1 Infusion Does Not Induce Aura or Headache in Migraine Patients With Aura. Headache\| PubMed ID: 31994720	2020
Vagus nerve stimulation inhibits cortical spreading depression exclusively through central mechanisms. Pain\| PubMed ID: 32142015	2020
Anti-migraine Calcitonin Gene-Related Peptide Receptor Antagonists Worsen Cerebral Ischemic Outcome in Mice. Annals of neurology\| PubMed ID: 32583883	2020
Acute sleep deprivation enhances susceptibility to the migraine substrate cortical spreading depolarization. The journal of headache and pain\| PubMed ID: 32631251	2020
Peri-Infarct Hot-Zones Have Higher Susceptibility to Optogenetic Functional Activation-Induced Spreading Depolarizations. Stroke\| PubMed ID: 32640946	2020
Sex and Genetic Background Effects on the Outcome of Experimental Intracranial Aneurysms. Stroke\| PubMed ID: 32912097	2020
Subarachnoid hemorrhage leads to early and persistent functional connectivity and behavioral changes in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 32936728	2021
Rapid hematoma growth triggers spreading depolarizations in experimental intracortical hemorrhage. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 32936730	2021
Therapeutic implications of cortical spreading depression models in migraine. Progress in brain research\| PubMed ID: 33008510	2020
Optogenetic Spreading Depression Elicits Trigeminal Pain and Anxiety Behavior. Annals of neurology\| PubMed ID: 33016466	2021
Intravascular Endothelin-1 does not trigger or increase susceptibility to Spreading Depolarizations. The journal of headache and pain\| PubMed ID: 33109086	2020
Optical coherence tomography of arteriolar diameter and capillary perfusion during spreading depolarizations. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 33593116	2021
Spreading depression as an innate antiseizure mechanism. Nature communications\| PubMed ID: 33850125	2021
Cerebral Amyloid Angiopathy-Related Transient Focal Neurologic Episodes. Neurology\| PubMed ID: 34016709	2021
Focal Subcortical White Matter Lesions Disrupt Resting State Cortical Interhemispheric Functional Connectivity in Mice. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 34037216	2021
Intracranial pressure spikes trigger spreading depolarizations. Brain : a journal of neurology\| PubMed ID: 34245240	2022
Cortical Spreading Depolarizations in a Mouse Model of Subarachnoid Hemorrhage. Neurocritical care\| PubMed ID: 34981426	2022
Migraine. Nature reviews. Disease primers\| PubMed ID: 35027572	2022
Correction to: Cortical Spreading Depolarizations in a Mouse Model of Subarachnoid Hemorrhage. Neurocritical care\| PubMed ID: 35041114	2022
Efficacy profile of noninvasive vagus nerve stimulation on cortical spreading depression susceptibility and the tissue response in a rat model. The journal of headache and pain\| PubMed ID: 35062860	2022
CADASIL mutations sensitize the brain to ischemia via spreading depolarizations and abnormal extracellular potassium homeostasis. The Journal of clinical investigation\| PubMed ID: 35202003	2022
Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition. The journal of headache and pain\| PubMed ID: 35282834	2022
The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results. Stroke\| PubMed ID: 35354299	2022
Rho-Kinase Inhibition Improves the Outcome of Focal Subcortical White Matter Lesions. Stroke\| PubMed ID: 35656825	2022
Microembolism and Other Links Between Migraine and Stroke: Clinical and Pathophysiologic Update. Neurology\| PubMed ID: 36522158	2023
Embracing Heterogeneity in The Multicenter Stroke Preclinical Assessment Network (SPAN) Trial. Stroke\| PubMed ID: 36601951	2023
Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation. bioRxiv : the preprint server for biology\| PubMed ID: 36824939	2023
Optogenetic Spreading Depolarizations Do Not Worsen Acute Ischemic Stroke Outcome. Stroke\| PubMed ID: 36876481	2023
Neurovascular coupling is preserved in chronic stroke recovery after targeted photothrombosis. NeuroImage. Clinical\| PubMed ID: 36948140	2023
Estrogen modulation of cortical spreading depression. The journal of headache and pain\| PubMed ID: 37237336	2023
Inhibition of persistent sodium current reduces spreading depression-evoked allodynia in a mouse model of migraine with aura. Pain\| PubMed ID: 37318029	2023
Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation. eLife\| PubMed ID: 37402178	2023
NAD precursor nutritional supplements sensitize the brain to future ischemic events. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 37434361	2023
The effect of sex and estrus cycle stage on optogenetic spreading depression induced migraine-like pain phenotypes. The journal of headache and pain\| PubMed ID: 37464297	2023
Spreading Depolarizations Suppress Hematoma Growth in Hyperacute Intracerebral Hemorrhage in Mice. Stroke\| PubMed ID: 37610105	2023
A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke. Science translational medicine\| PubMed ID: 37729432	2023
Vagus Nerve Stimulation in Ischemic Stroke. Current neurology and neuroscience reports\| PubMed ID: 38008851	2023
Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations. Neurology. Genetics\| PubMed ID: 38179414	2024
Non-Invasive Vagal Nerve Stimulation Pre-Treatment Reduces Neurological Dysfunction After Closed Head Injury in Mice. Neurotrauma reports\| PubMed ID: 38435077	2024
Thrombolysis increases the risk of persistent headache attributed to ischemic stroke: A prospective observational study. Brain and behavior\| PubMed ID: 38450944	2024
Mechanism of Action and Translational Potential of ()-Meclizine in Preemptive Prophylaxis Against Stroke. Stroke\| PubMed ID: 38572656	2024
The novel ROCK2 selective inhibitor NRL-1049 preserves the blood-brain barrier after acute injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 38833563	2024
Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial. Circulation research\| PubMed ID: 39034919	2024
Hippocampal infarction and generalized seizures predict early mortality after endovascular middle cerebral artery occlusion in mice. Experimental neurology\| PubMed ID: 39079623	2024
Optogenetic Functional Activation Is Detrimental During Acute Ischemic Stroke in Mice. Stroke\| PubMed ID: 39234742	2024
Oxytocin shortens spreading depolarization-induced periorbital allodynia. The journal of headache and pain\| PubMed ID: 39289629	2024
Correction: Oxytocin shortens spreading depolarization-induced periorbital allodynia. The journal of headache and pain\| PubMed ID: 39434018	2024
Impact of intracranial hypertension and cerebral perfusion pressure on spreading depolarization. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 39501698	2025
Inhibition of nitric oxide synthase transforms carotid occlusion-mediated benign oligemia into large cerebral infarction. Theranostics\| PubMed ID: 39744690	2025
Isoform-selective and non-selective rho-kinase inhibitors do not affect collagenase-induced intracerebral hemorrhage outcomes in mice: Influence of sex and circadian cycle. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 39763388	2025
Impaired Resting-State Functional Connectivity in Cerebral Autosomal-Dominant Arteriopathy, Subcortical Infarcts, and Leukoencephalopathy Mutant Mice. Stroke\| PubMed ID: 39882613	2025
Examination of Inter-α Inhibitor Proteins in Permanent and Transient Focal Ischemia. Journal of the American Heart Association\| PubMed ID: 39921503	2025
Uric Acid Stroke Cerebroprotection Transcended Sex, Age, and Comorbidities in a Multicenter Preclinical Trial. Stroke\| PubMed ID: 40091742	2025
Determinants of Outcome After Endovascular Middle Cerebral Artery Occlusion in Rats in the SPAN Trial. Stroke\| PubMed ID: 40396268	2025
Multicenter SPAN Trial of Fasudil in Ischemic Stroke. Stroke\| PubMed ID: 40421536	2025
The mysterious link between migraine aura and migraine headache. PLoS biology\| PubMed ID: 40498799	2025
Small-molecule CGRP antagonist atogepant does not affect cortical spreading depression susceptibility in rats. The journal of headache and pain\| PubMed ID: 40764901	2025
Spreading depolarization as a therapeutic target in migraine. Nature reviews. Neurology\| PubMed ID: 40813918	2025
Brain Endothelial Soluble ST2 Production and Cerebral Edema in a Rat Model of Ischemic Stroke. Annals of neurology\| PubMed ID: 40833219	2025
Oral atogepant mitigates spreading depolarization-induced pain and anxiety behavior in mice. The journal of headache and pain\| PubMed ID: 40841621	2025
Fingolimod as a Potential Cerebroprotectant Results From the Stroke Preclinical Assessment Network. Stroke\| PubMed ID: 40899256	2025
Preclinical Ischemic Stroke Multicenter (PRISM) Trials Collective Statement: Opportunities, Challenges, and Recommendations for a New Era. Stroke\| PubMed ID: 40931817	2025
Multicenter Stroke Preclinical Assessment Network Analysis of Cardiovascular Risk Factor Subgroups Treated With the Poly(ADP-Ribose) Polymerase Inhibitor Veliparib. Journal of the American Heart Association\| PubMed ID: 40996065	2025
Olfactory Bulb Pinprick Induction of Cortical Spreading Depolarizations. bioRxiv : the preprint server for biology\| PubMed ID: 41000948	2025
Evaluating tocilizumab in ischemic stroke: Findings from the SPAN multicenter trial. Neuropharmacology\| PubMed ID: 41354124	2025