J. Craft

Department of Immunobiology, Yale University School of Medicine

Affiliated withYale University School of Medicine Yale University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Biochemical and immunological heterogeneity of the Ro ribonucleoprotein particles. Analysis with sera specific for the RohY5 particle. The Journal of clinical investigation\| PubMed ID: 2472427	1989
The U2 small nuclear ribonucleoprotein particle as an autoantigen. Analysis with sera from patients with overlap syndromes. The Journal of clinical investigation\| PubMed ID: 2968364	1988
Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmunogenic target. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 7514640	1994
T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice. The Journal of experimental medicine\| PubMed ID: 7540652	1995
Safety and immunogenicity of an outer surface protein A vaccine in subjects with previous Lyme disease. The Journal of infectious diseases\| PubMed ID: 7594671	1995
Autoantigenic epitopes of the B and D polypeptides of the U1 snRNP. Analysis of domains recognized by the Y12 monoclonal anti-Sm antibody and by patient sera. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 7682245	1993
B cells process and present lupus autoantigens that initiate autoimmune T cell responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 8301145	1994
Identification of autoantibodies to RNA polymerase II. Occurrence in systemic sclerosis and association with autoantibodies to RNA polymerases I and III. The Journal of clinical investigation\| PubMed ID: 8390487	1993
Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. The Journal of biological chemistry\| PubMed ID: 8463290	1993
Protective antibodies in murine Lyme disease arise independently of CD40 ligand. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 8683101	1996
Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantibody responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 8683147	1996
Revisiting autoantibody profiles in systemic lupus erythematosus. The Journal of rheumatology\| PubMed ID: 9034986	1997
alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 9036998	1997
A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice. The Journal of experimental medicine\| PubMed ID: 9064331	1996
Roles of interferon-gamma and interleukin-4 in murine lupus. The Journal of clinical investigation\| PubMed ID: 9109438	1997
Central T cell tolerance in lupus-prone mice: influence of autoimmune background and the lpr mutation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 9834135	1998
Roles of Fas and Fas ligand during mammary gland remodeling. The Journal of clinical investigation\| PubMed ID: 11086022	2000
CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus. The Journal of experimental medicine\| PubMed ID: 11157053	2001
Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways. The Journal of biological chemistry\| PubMed ID: 12107190	2002
IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12928402	2003
Age-dependent requirement for gammadelta T cells in the primary but not secondary protective immune response against an intestinal parasite. The Journal of experimental medicine\| PubMed ID: 14597739	2003
Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14707107	2004
The centromeric region of chromosome 7 from MRL mice (Lmb3) is an epistatic modifier of Fas for autoimmune disease expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14978078	2004
Age-associated change in the frequency of memory CD4+ T cells impairs long term CD4+ T cell responses to influenza vaccine. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15210831	2004
Naive CD4+ T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15814741	2005
Editing antigen presentation: antigen transfer between human B lymphocytes and macrophages mediated by class A scavenger receptors. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18768860	2008
In vivo regulation of Bcl6 and T follicular helper cell development. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20519643	2010
Follicular helper T cells in immunity and systemic autoimmunity. Nature reviews. Rheumatology\| PubMed ID: 22549246	2012
Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells. Immunity\| PubMed ID: 24631156	2014
CD4+ T cell help guides formation of CD103+ lung-resident memory CD8+ T cells during influenza viral infection. Immunity\| PubMed ID: 25308332	2014
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity\| PubMed ID: 26410627	2015
IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26519529	2015
Disruption of Pathogenic Cellular Networks by IL-21 Blockade Leads to Disease Amelioration in Murine Lupus. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28219887	2017
Interleukin-10 from CD4 follicular regulatory T cells promotes the germinal center response. Science immunology\| PubMed ID: 29054998	2017
STAT4 and T-bet control follicular helper T cell development in viral infections. The Journal of experimental medicine\| PubMed ID: 29212666	2018
Human Extrafollicular CD4 Th Cells Help Memory B Cells Produce Igs. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 30030323	2018
ELF4 facilitates innate host defenses against by activating transcription of and . The Journal of biological chemistry\| PubMed ID: 30898878	2019
Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function. Nature\| PubMed ID: 31217581	2019
Spatial and functional heterogeneity of follicular helper T cells in autoimmunity. Current opinion in immunology\| PubMed ID: 31374450	2019
Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function. Nature\| PubMed ID: 31447485	2019
Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis. Science translational medicine\| PubMed ID: 31748230	2019
Kidney tissue hypoxia dictates T cell-mediated injury in murine lupus nephritis. Science translational medicine\| PubMed ID: 32269165	2020
Repeat tick exposure elicits distinct immune responses in guinea pigs and mice. Ticks and tick-borne diseases\| PubMed ID: 32993942	2020
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA neurology\| PubMed ID: 33074286	2021
CD4+ follicular regulatory T cells optimize the influenza virus-specific B cell response. The Journal of experimental medicine\| PubMed ID: 33326020	2021
Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses. Cell\| PubMed ID: 34852236	2021
Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers. Immunity\| PubMed ID: 35090581	2022
A current review of spinal meningiomas: epidemiology, clinical presentation and management. Journal of neuro-oncology\| PubMed ID: 36637710	2023
Association of frailty with healthcare resource utilization after open thoracic/thoracolumbar posterior spinal fusion for adult spinal deformity. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society\| PubMed ID: 36949143	2023
Impact of insurance status on healthcare resource utilization and outcomes in adolescent patients presenting with spinal cord injuries. Journal of neurosurgery. Pediatrics\| PubMed ID: 37021755	2023
Association Between Intravenous to Oral Opioid Transition Time and Length of Hospital Stay After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. International journal of spine surgery\| PubMed ID: 37076256	2023
Cutting Edge: IL-21 and Tissue-Specific Signals Instruct Tbet+CD11c+ B Cell Development following Viral Infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 37133336	2023
T follicular helper cells in cancer, tertiary lymphoid structures, and beyond. Seminars in immunology\| PubMed ID: 37343412	2023
IL-27 gives a good gut feeling about immune regulation. Nature immunology\| PubMed ID: 37932458	2023
T Follicular Helper Cell Heterogeneity. Annual review of immunology\| PubMed ID: 38060987	2024
Impact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery. Journal of clinical medicine\| PubMed ID: 38202121	2023
Association of Malnutrition with Surgical and Hospital Outcomes after Spine Surgery for Spinal Metastases: A National Surgical Quality Improvement Program Study of 1613 Patients. Journal of clinical medicine\| PubMed ID: 38541767	2024
CBLs downregulation foretells T cell ubiquitination leading to autoimmunity. Cell chemical biology\| PubMed ID: 39029453	2024
Impact of preoperative nutritional status on morbidity and mortality in elderly patients undergoing subdural hematoma evacuation: the role of the Geriatric Nutritional Risk Index. Journal of neurosurgery\| PubMed ID: 39546774	2025
Association of Safety-Net hospital status and hospital outcomes following ACDF or PCDF for CSM. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia\| PubMed ID: 39742780	2025
A Honduran Prevalence Study on Soil-Transmitted Helminths Highlights Serological Antibodies to Tm-WAP49 as a Diagnostic Marker for Exposure to Human Trichuriasis. The American journal of tropical medicine and hygiene\| PubMed ID: 39933187	2025
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. Genome biology\| PubMed ID: 40676597	2025
Sequential class switching generates antigen-specific gut IgA from IgG1 B cells. Immunity\| PubMed ID: 41253159	2025