retrospective-observational-study-computed-tomography-based-vascular

Retrospective Observational Study of Computed Tomography-Based Vascular Risk Assessment During Needle Drainage of Peritonsillar Abscess

Peritonsillar abscess (PTA) is a common deep neck infection in which bedside drainage is performed close to major cervical vessels. Although catastrophic ...

University of Health Sciences Gazi Yasargil Training and Research Hospital

Mucormycosis is a life-threatening fungal infection, where rapid diagnosis is critical. We developed a deep learning approach using paranasal computed tomography (CT) images to test whether mucormycosis can be detected automatically, potentially aiding or expediting the diagnostic process that traditionally relies on biopsy.

Automated Mucormycosis Diagnosis from Paranasal CT Using ResNet50 and ConvNeXt Small.

 Lateral osteotomies in rhinoplasty run adjacent to the lacrimal drainage system (LDS), risking postoperative tearing. Piezoelectric (piezo) devices enable precise bone cuts that may reduce LDS trauma. We compared the 1-month incidence of objective lacrimal dysfunction after piezo versus classic osteotomy.  Retrospective, single-center controlled cohort (1 January 2024-1 January 2025) at a tertiary ENT clinic. Consecutive patients aged 19-45 with pre-operative paranasal sinus CT and no prior lacrimal disorder were grouped by osteotomy technique (piezo vs. classic;  = 65 per arm). Assessments were performed at postoperative day 7-10 and at 1, 3, and 6-12 months. The primary endpoint was 1-month objective lacrimal dysfunction, defined as fluorescein dye disappearance test (FDDT) grade ≥1 or reflux/resistance on irrigation plus symptoms (Munk ≥2). Pre-specified statistical tests were used.  Early tearing favored piezo. At week 1, epiphora occurred in 32.3% with piezo versus 46.1% with classic ( = 0.041); by month 6, rates were 4.6% versus 15.1% ( = 0.031). Differences at months 1 and 3 also favored piezo but were not statistically significant ( = 0.062 and  = 0.088). FDDT positivity was lower with piezo at week 1 (23.0% vs. 38.4%,  = 0.045) and month 6 (3.0% vs. 10.7%,  = 0.048). Irrigation obstruction was less frequent with piezo at week 1 (7.6% vs. 21.5%,  = 0.026), but groups converged by months 1 (15.4% vs. 12.3%,  = 0.80) and 3 (6.2% vs. 4.6%,  > 0.99). Punctum stenosis/occlusion remained uncommon in both groups without significant differences.  Piezo-assisted lateral osteotomy is associated with less early lacrimal dysfunction and lower 6-month epiphora compared with the classic technique. Convergence of irrigation findings by 1-3 months suggests postoperative edema as the dominant transient mechanism. Given the retrospective, single-center design and low event rates, multicenter prospective studies powered for early LDS outcomes are warranted.

The Effect of Piezoelectric (Piezo) Versus Classic Lateral Osteotomy on the Lacrimal Drainage System (LDS): A Retrospective, Single-Center, Controlled Study.

 Hearing loss is a prevalent sensory impairment with substantial psychosocial consequences. This cross-sectional study investigated the relationship between audiometric hearing loss and mood disturbances in adults aged 18-65 years who reported hearing difficulties for at least six months.  Objective hearing level was assessed using the better-ear pure-tone average (PTA), and subjective hearing handicap was measured with the Hearing Handicap Inventory for Adults (HHIA). Standardized mood assessments included the Beck Depression Inventory-II (BDI-II) and the Beck Anxiety Inventory (BAI).  The study found that higher HHIA scores, indicating greater perceived hearing handicap, were strongly correlated with more severe depression and anxiety (ρ ≈ 0.45 and 0.38, respectively;  < 0.001). In contrast, objective PTA showed weaker associations with mood scores. Regression analyses, adjusted for age and gender, confirmed that perceived hearing handicap (HHIA) was the strongest independent predictor of both depression (standardized β ≈ 0.37,  < 0.001) and anxiety (β ≈ 0.33,  < 0.01), accounting for about 30% of the variance in mood scores. Nearly one-third of participants had clinically significant depression (BDI-II ≥ 20), which is substantially higher than community norms. The cross-sectional design and potential selection bias are limitations.  Even mild-to-moderate hearing loss can result in significant depressive and anxious symptoms when individuals perceive themselves as handicapped. Early identification of hearing problems, routine psychosocial screening (e.g., a simple two-question survey), and integrated care are essential for improving quality of life.

Article	Year
Automated Mucormycosis Diagnosis from Paranasal CT Using ResNet50 and ConvNeXt Small. Bioengineering (Basel, Switzerland)\| PubMed ID: 40868367	2025
The Effect of Piezoelectric (Piezo) Versus Classic Lateral Osteotomy on the Lacrimal Drainage System (LDS): A Retrospective, Single-Center, Controlled Study. Medicina (Kaunas, Lithuania)\| PubMed ID: 41303816	2025
When Sound Fades: Depression and Anxiety in Adults with Hearing Loss-A Cross-Sectional Study. Healthcare (Basel, Switzerland)\| PubMed ID: 41464387	2025

Serkan Dedeoglu

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