Juan R. Rodriguez-Madoz

Hemato-Oncology Program, Cima Universidad de Navarra, IdiSNA

Affiliated withCima Universidad de Navarra, IdiSNA Centro de Investigacion Biomedica en Red de Cancer (CIBERONC)Cancer Center Clinica Universidad de Navarra (CCUN)

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin. International journal of pharmaceutics\| PubMed ID: 25708005	2015
Generation and characterization of human iPSC line generated from mesenchymal stem cells derived from adipose tissue. Stem cell research\| PubMed ID: 27345779	2016
Generation and characterization of human iPSC lines derived from a Primary Hyperoxaluria Type I patient with p.I244T mutation. Stem cell research\| PubMed ID: 27345794	2016
CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I. Nature communications\| PubMed ID: 30575740	2018
Generation of an induced pluripotent stem cell line (CIMAi001-A) from a compound heterozygous Primary Hyperoxaluria Type I (PH1) patient carrying p.G170R and p.R122* mutations in the AGXT ge... Stem cell research\| PubMed ID: 31715429	2019
Small Molecule-Based Enzyme Inhibitors in the Treatment of Primary Hyperoxalurias. Journal of personalized medicine\| PubMed ID: 33513899	2021
Online monitoring of hiPSC expansion and hepatic differentiation in 3D culture by dielectric spectroscopy. Biotechnology and bioengineering\| PubMed ID: 33713416	2021
Generation of NKX2.5 Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts. Frontiers in cell and developmental biology\| PubMed ID: 35127713	2021
CRISPR-Cas9 inhibition of hepatic LDH as treatment of primary hyperoxaluria. Molecular therapy. Methods & clinical development\| PubMed ID: 35402636	2022
Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside? Journal for immunotherapy of cancer\| PubMed ID: 35577501	2022
FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 36045586	2023
CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome. Science advances\| PubMed ID: 36179026	2022
Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia. Frontiers in immunology\| PubMed ID: 37795087	2023
Molecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in multiple myeloma. Blood advances\| PubMed ID: 39058976	2024
Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells. bioRxiv : the preprint server for biology\| PubMed ID: 39314273	2025
Oxygen control in bioreactor drives high yield production of functional hiPSC-like hepatocytes for advanced liver disease modelling. Scientific reports\| PubMed ID: 39427033	2024
First-in-class transactivator-free, doxycycline-inducible IL-18-engineered CAR-T cells for relapsed/refractory B cell lymphomas. Molecular therapy. Nucleic acids\| PubMed ID: 39640015	2024
Beyond precision: evaluation of off-target clustered regularly interspaced short palindromic repeats/Cas9-mediated genome editing. Cytotherapy\| PubMed ID: 39652018	2025
Generation and GMP scale-up of human CAR-T cells using non-viral transposons for B cell malignances. Molecular therapy. Methods & clinical development\| PubMed ID: 40034423	2025
Discovery and preclinical development of a SdAb-based CAR-T technology for targeting CD33 in AML. Molecular therapy. Oncology\| PubMed ID: 40084273	2025
Implication of bone marrow adipose tissue in bone homeostasis during osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 40154729	2025
Chaperone-mediated autophagy sustains pericyte stemness necessary for brain tissue homeostasis. Journal of advanced research\| PubMed ID: 40286844	2025
European survey on CAR T-Cell analytical methods from apheresis to post-infusion immunomonitoring. Frontiers in immunology\| PubMed ID: 40342422	2025
Genetic Engineering in CAR T Cells for Solid Tumors: Current State, Barriers and Future Developments. Human gene therapy\| PubMed ID: 40880317	2025
Systematic production of human kidney organoids for transplantation in porcine kidneys during ex vivo machine perfusion. Nature biomedical engineering\| PubMed ID: 41174010	2025