Yimei Du

Department of Cardiology, Huazhong University of Science and Technology

Affiliated withHuazhong University of Science and Technology Key Lab for Biological Targeted Therapy of Education Ministry

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Inhibitory effect of adrenomedullin on L-type calcium currents in guinea-pig ventricular myocytes. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 12506319	2002
Effects of platelet activating factor on action potentials and potassium channels in guinea-pig ventricular myocytes. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 15224138	2004
[Chronic intermittent hypoxia decreases acute hypoxic inhibition of voltage-gated potassium channel in rat pulmonary arterial smooth muscle cells]. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 15497045	2004
[Isolation and electrophysiological characteristics of embryonic cardiomyocytes in mice]. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 15497049	2004
Action of aluminum on high voltage-dependent calcium current and its modulation by ginkgolide B. Acta pharmacologica Sinica\| PubMed ID: 15842770	2005
Characterization of monoclonal antibody to L-homocysteic acid and its immunohistochemistry in rat hippocampus. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban\| PubMed ID: 15934293	2005
Electropharmacological properties of telmisartan in blocking hKv1.5 and HERG potassium channels expressed on Xenopus laevis oocytes. Acta pharmacologica Sinica\| PubMed ID: 18664324	2008
Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 18690396	2008
The role of hERG1 K+ channels and a functional link between hERG1 K+ channels and SDF-1 in acute leukemic cell migration. Experimental cell research\| PubMed ID: 19409379	2009
Glycyrretinic acid blocks cardiac sodium channels expressed in Xenopus oocytes. Journal of ethnopharmacology\| PubMed ID: 19559778	2009
Molecular determinants of Kv1.5 channel block by diphenyl phosphine oxide-1. Journal of molecular and cellular cardiology\| PubMed ID: 20184887	2010
Aconitine blocks HERG and Kv1.5 potassium channels. Journal of ethnopharmacology\| PubMed ID: 20600762	2010
Arrhythmogenic autoantibodies against calcium channel lead to sudden death in idiopathic dilated cardiomyopathy. European journal of heart failure\| PubMed ID: 21044990	2011
Effects of acetylcholine on electrical remodeling of human atrial fibers. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban\| PubMed ID: 21505977	2011
Effect of tumor necrosis factor-Î± on neutralization of ventricular fibrillation in rats with acute myocardial infarction. Mediators of inflammation\| PubMed ID: 21584281	2011
Agonist-like autoantibodies against calcium channel in patients with dilated cardiomyopathy. Heart and vessels\| PubMed ID: 21814855	2012
Imatinib has the potential to exert its antileukemia effects by down-regulating hERG1 K+ channels in chronic myelogenous leukemia. Medical oncology (Northwood, London, England)\| PubMed ID: 22161019	2012
18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels. Acta pharmacologica Sinica\| PubMed ID: 22609834	2012
Hypoxia induces voltage-gated K+ (Kv) channel expression in pulmonary arterial smooth muscle cells through hypoxia-inducible factor-1 (HIF-1). Bosnian journal of basic medical sciences\| PubMed ID: 22938542	2012
Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate. Biological & pharmaceutical bulletin\| PubMed ID: 23196655	2013
18β-Glycyrrhetinic acid potently inhibits Kv1.3 potassium channels and T cell activation in human Jurkat T cells. Journal of ethnopharmacology\| PubMed ID: 23707333	2013
Potent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells. PloS one\| PubMed ID: 23717641	2013
Role of voltage-gated potassium channels in pathogenesis of chronic pulmonary heart disease. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban\| PubMed ID: 24142714	2013
Open conformation of hERG channel turrets revealed by a specific scorpion toxin BmKKx2. Cell & bioscience\| PubMed ID: 24725272	2014
Effect of tumor necrosis factor-α on ventricular arrhythmias in rats with acute myocardial infarction in vivo. World journal of emergency medicine\| PubMed ID: 25214942	2010
Acacetin blocks kv1.3 channels and inhibits human T cell activation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 25301362	2014
Activation of Transient Receptor Potential Vanilloid 4 is Involved in Neuronal Injury in Middle Cerebral Artery Occlusion in Mice. Molecular neurobiology\| PubMed ID: 25399955	2016
MicroRNA-101a inhibits cardiac fibrosis induced by hypoxia via targeting TGFβRI on cardiac fibroblasts. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 25591764	2015
[Combined transgenic inhibition of CaMKII and Ik1 on cardiac remodeling]. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 25896051	2015
Interleukin-17A contributes to the development of post-operative atrial fibrillation by regulating inflammation and fibrosis in rats with sterile pericarditis. International journal of molecular medicine\| PubMed ID: 25955429	2015
Novel heterozygous mutation c.4282G>T in the gene in a family with Brugada syndrome. Experimental and therapeutic medicine\| PubMed ID: 26136871	2015
Vaccination against type 1 angiotensin receptor prevents streptozotocin-induced diabetic nephropathy. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 26407577	2016
[Effect of Kv1.3 and KCa3.1 potassium ion channels on the proliferation and migration of monocytes/macrophages]. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 26490068	2015
Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties. Scientific reports\| PubMed ID: 26616555	2015
Blockage of K(Ca)3.1 and Kv1.3 channels of the B lymphocyte decreases the inflammatory monocyte chemotaxis. International immunopharmacology\| PubMed ID: 26795234	2016
Signal Transducer and Activator of Transcription 3/MicroRNA-21 Feedback Loop Contributes to Atrial Fibrillation by Promoting Atrial Fibrosis in a Rat Sterile Pericarditis Model. Circulation. Arrhythmia and electrophysiology\| PubMed ID: 27406600	2016
Transient Receptor Potential Vanilloid 4 Inhibits γ-Aminobutyric Acid-Activated Current in Hippocampal Pyramidal Neurons. Frontiers in molecular neuroscience\| PubMed ID: 27616980	2016
Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus. Molecular neurobiology\| PubMed ID: 27660267	2017
Enhanced Oxidative Stress Is Responsible for TRPV4-Induced Neurotoxicity. Frontiers in cellular neuroscience\| PubMed ID: 27799895	2016
Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice. Scientific reports\| PubMed ID: 28205608	2017
Activation of transient receptor potential vanilloid 4 involves in hypoxia/reoxygenation injury in cardiomyocytes. Cell death & disease\| PubMed ID: 28542130	2017
Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 29439248	2018
A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension. Journal of geriatric cardiology : JGC\| PubMed ID: 29581716	2017
Atrial Fibrillation Recurrence and Peri-Procedural Complication Rates in nMARQ vs. Conventional Ablation Techniques: A Systematic Review and Meta-Analysis. Frontiers in physiology\| PubMed ID: 29892228	2018
Quantification of Beat-To-Beat Variability of Action Potential Durations in Langendorff-Perfused Mouse Hearts. Frontiers in physiology\| PubMed ID: 30538638	2018
Mutation in causes atrial fibrillation by activating inflammation and cardiac fibrosis in a knock-in rat model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31034774	2019
TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice. Cell death & disease\| PubMed ID: 31097691	2019
Author Correction: TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice. Cell death & disease\| PubMed ID: 31227687	2019
Blockade of Transient Receptor Potential Vanilloid 4 Enhances Antioxidation after Myocardial Ischemia/Reperfusion. Oxidative medicine and cellular longevity\| PubMed ID: 31308876	2019
Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury Suppression of Transient Receptor Potential Vanilloid 4 Channel. Frontiers in pharmacology\| PubMed ID: 31636563	2019
Colchicine prevents atrial fibrillation promotion by inhibiting IL-1β-induced IL-6 release and atrial fibrosis in the rat sterile pericarditis model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 32554248	2020
TRPV4 blockade suppresses atrial fibrillation in sterile pericarditis rats. JCI insight\| PubMed ID: 33119551	2020
Transient receptor potential vanilloid 4 activation inhibits the delayed rectifier potassium channels in hippocampal pyramidal neurons: An implication in pathological changes following piloc... Journal of neuroscience research\| PubMed ID: 33393091	2021
A novel LMNA indel mutation identified in a family with atrioventricular block and atrial fibrillation. Medicine\| PubMed ID: 34106654	2021
Involvement of TRPV4 in changes in rapidly inactivating potassium channels in the early stage of pilocarpine-induced status epilepticus in mice. Journal of cellular physiology\| PubMed ID: 34415059	2022
Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts. Cell calcium\| PubMed ID: 34628110	2021
Electrophysiological and Proarrhythmic Effects of Hydroxychloroquine Challenge in Guinea-Pig Hearts. ACS pharmacology & translational science\| PubMed ID: 34661080	2021
Identification of the distinctive role of DPT in dilated cardiomyopathy: a study based on bulk and single-cell transcriptomic analysis. Annals of translational medicine\| PubMed ID: 34733953	2021
Measures of repolarization variability predict ventricular arrhythmogenesis in heptanol-treated Langendorff-perfused mouse hearts. Current research in physiology\| PubMed ID: 34746832	2021
Interleukin-6-Mediated-Ca Handling Abnormalities Contributes to Atrial Fibrillation in Sterile Pericarditis Rats. Frontiers in immunology\| PubMed ID: 34975847	2021
Blockage of transient receptor potential vanilloid 4 prevents postoperative atrial fibrillation by inhibiting NLRP3-inflammasome in sterile pericarditis mice. Cell calcium\| PubMed ID: 35439615	2022
The Potential of Metabolism-Related Gene OGDHL as a Biomarker for Myocardial Remodeling in Dilated Cardiomyopathy. Frontiers in cardiovascular medicine\| PubMed ID: 35463769	2022
Mechanisms of ventricular arrhythmias elicited by coexistence of multiple electrophysiological remodeling in ischemia: A simulation study. PLoS computational biology\| PubMed ID: 35476614	2022
[Oral administration of TRPV4 inhibitor improves atrial calcium handling abnormalities in sterile pericarditis rats]. Sheng li xue bao : [Acta physiologica Sinica]\| PubMed ID: 35503066	2022
Mog1 deficiency promotes cardiac contractile dysfunction and isoproterenol-induced arrhythmias associated with cardiac fibrosis and Cx43 remodeling. Biochimica et biophysica acta. Molecular basis of disease\| PubMed ID: 35533905	2022
Activation of transient receptor potential vanilloid 4 is involved in pressure overload-induced cardiac hypertrophy. eLife\| PubMed ID: 35731090	2022
Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus. Cellular and molecular neurobiology\| PubMed ID: 35840809	2023
Heterogeneities in Ventricular Conduction Following Treatment with Heptanol: A Multi-Electrode Array Study in Langendorff-Perfused Mouse Hearts. Life (Basel, Switzerland)\| PubMed ID: 35888085	2022
Comprehensive bioinformatics analysis reveals common potential mechanisms, progression markers, and immune cells of coronary virus disease 2019 and atrial fibrillation. Frontiers in cardiovascular medicine\| PubMed ID: 36352845	2022
A risk model developed based on necroptosis to assess progression for ischemic cardiomyopathy and identify possible therapeutic drugs. Frontiers in pharmacology\| PubMed ID: 36518671	2022
Inhibition of phosphoglycerate kinase 1 attenuates autoimmune myocarditis by reprogramming CD4+ T cell metabolism. Cardiovascular research\| PubMed ID: 36726197	2023
Advances in basic and translational research in atrial fibrillation. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 37122214	2023
Transient receptor potential vanilloid 4 (TRPV4) in neutrophils enhances myocardial ischemia/reperfusion injury. Journal of leukocyte biology\| PubMed ID: 37232941	2023
Comparison of the efficacy and safety of benzbromarone and febuxostat in gout and hyperuricemia: a systematic review and meta-analysis. Clinical rheumatology\| PubMed ID: 38492092	2024
Acacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration. Chinese medicine\| PubMed ID: 38741130	2024
TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology\| PubMed ID: 39312069	2025
Prognostic signature and therapeutic drug identification for dilated cardiomyopathy based on necroptosis via bioinformatics and experimental validation. Scientific reports\| PubMed ID: 39747333	2025
Interleukin-6: Molecular Mechanisms and Therapeutic Perspectives in Atrial Fibrillation. Current medical science\| PubMed ID: 40035997	2025
Activation of transient receptor potential vanilloid 4 impairs long-term depression in nucleus accumbens and induces depressive-like behavior. Neuropharmacology\| PubMed ID: 40154945	2025
Transient receptor potential vanilloid 4 blockage attenuates pyroptosis in hippocampus of mice following pilocarpine‑induced status epilepticus. Acta neuropathologica communications\| PubMed ID: 40205503	2025
TRPV4 inhibition suppresses myocardial ischemia-reperfusion arrhythmia of mice by alleviating calcium handling abnormalities. Heart rhythm\| PubMed ID: 40246044	2025
Coupling of USP10 de-ubiquitination and chaperone-mediated autophagy causes cardiac sodium channel degradation and cardiac arrhythmias. Cardiovascular research\| PubMed ID: 41213870	2025
Inhibition of transient receptor potential vanilloid 4: A promising novel strategy for myocardial ischemia/reperfusion injury treatment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 41218341	2025
Activation of Endothelial TRPV4 Exacerbates Myocardial Ischemia-Reperfusion Injury via Vascular Integrity Impairment. The Canadian journal of cardiology\| PubMed ID: 41238115	2025