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Therapeutic Effects of Gualou Guizhi Antispasmodic Granules on Spasticity and PANoptosis in a Rat Model of Spinal Cord Injury

Muscle spasticity after spinal cord injury (SCI) severely impacts quality of life, with limited effective treatments. Gualou Guizhi Antispasmodic Granules ...

Second Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine

We performed a proof of concept trial to evaluate relative safety and efficacy of Rhodiola Capsule for mild to moderate major depressive disorder(MDD).

Antidepressants effects of Rhodiola capsule combined with sertraline for major depressive disorder: A randomized double-blind placebo-controlled clinical trial.

Dizziness is a common symptom in adults and usually due to peripheral causes affecting semicircular canal function or central causes affecting the pons, medulla, or cerebellum. Arrhythmia is a recognized cause of dizziness in people with structural or ischemic heart disease. We report a case of exercise-induced transient ventricular tachycardia and dizziness in a man with no evidence of organic heart disease.

Transient ventricular arrhythmia as a rare cause of dizziness during exercise: A case report.

Traditional Chinese Medicine (TCM) has gained global attention, particularly after Professor Youyou Tu was awarded the Nobel Prize for her discovery of artemisinin as a treatment for malaria. However, the theory behind TCM is often perceived as a "black-box" with complex components and an unclear structure and mechanism of action. This had hindered the development of TCM within the framework of modern medicine.

Development of modern Chinese medicine guided by molecular compatibility theory.

Tumor immune escape presents a significant challenge in cancer treatment, characterized by the upregulation of immune inhibitory molecules and dysfunction of immune cells. Tumor immunotherapy seeks to restore normal anti-tumor immune responses to control and eliminate tumors effectively. The active ingredients of traditional Chinese medicine (TCM) demonstrate a variety of anti-tumor activities and mechanisms, including the modulation of immune cell functions and inhibiting tumor-related suppressive factors, thereby potentially enhancing anti-tumor immune responses. Furthermore, nano-delivery systems function as efficient carriers to enhance the bioavailability and targeted delivery of TCM active ingredients, augmenting therapeutic efficacy. This review comprehensively analyzes the impact of TCM active ingredients on the immune system and explores the synergistic application of nano-delivery systems in combination with TCM active ingredients for enhancing tumor immunotherapy.

Article	Year
Antidepressants effects of Rhodiola capsule combined with sertraline for major depressive disorder: A randomized double-blind placebo-controlled clinical trial. Journal of affective disorders\| PubMed ID: 32090788	2020
Transient ventricular arrhythmia as a rare cause of dizziness during exercise: A case report. World journal of clinical cases\| PubMed ID: 34786406	2021
Development of modern Chinese medicine guided by molecular compatibility theory. Journal of advanced research\| PubMed ID: 39111627	2025
Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy. Journal of nanobiotechnology\| PubMed ID: 40382641	2025

Lili Gao

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