an-animal-model-pulpitis-based-on-an-outbred-mice-strain-its

An Animal Model of Pulpitis Based on an Outbred Mice Strain and Its Histological Analysis

The Naval Medical Research Institute (NMRI) mice have not been reported previously for creating a dental pulp inflammation model. In this protocol, we ...

Dow University of Health Sciences

Obesity is a state of abnormal accumulation of fat in adipose tissues of the body to the level that one's health is adversely compromised. Tripathi et al. state (according to WHO) that obesity is now considered the fifth leading cause of mortality in the world. Caries is a multifactorial disease and one of the major oral health issues of the modern era affecting people around the globe. Rise in dental caries has been observed in developing countries as a result of factors including increased intake of carbohydrates. The present study aims for assessing the association of DMFT with BMI, age, and gender. This study was conducted in the dental OPD of the Dow University of Health Sciences, Karachi, from February 2016 till January 2017. A custom-made interview-based questionnaire was used to assess BMI, DMFT, and sociodemographics. The sample size was kept at 385. Age was reported as a strong predictor ( 0.641) of DMFT followed by BMI and gender as the weakest predictors. Age and BMI had statistically significant association with DMFT scores, which shows that diet patterns may affect general health. High caloric intake over long periods affects BMI and also oral health.

Deciphering Possible Association of Risk Factors for Dental Caries in Pakistani Population.

A case of unusual anatomy in a maxillary lateral incisor is presented. A 20-year old female presented with failing endodontics. Clinical examination and radiographs revealed poorly obturated maxillary left lateral incisor with an untreated patent second root and a palatogingival groove. A decision was made to treat the tooth non-surgically. After removing gutta-percha from main canal, the orifice of second root could not be located from inside the chamber. After determining the position of this root to be mesial and palatal to main canal, gingival tissue was removed from mesio-palatal side and access was extended to include the cingulum and orifice was located mesio-palatally. This canal was mechanically prepared and both canals were filled with calcium hydroxide. Three weeks later when symptoms subsided, the canals were obturated using the warm vertical technique. However, patient returned after a month complaining of pain and pus discharge. The tooth was surgically retreated; the enucleation was performed without root end resection. Patient returned after two years and reported complete healing but with mild discoloration of crown which was treated with walking bleach technique.

Combined Endodontic and Surgical Management of Twin Rooted Maxillary Lateral Incisor with a Palatogingival Groove.

The objective of this in-vitro study was to compare the erosive potential and smear layer removal ability of 1% Phytic acid (IP6) and 17% Ethylenediaminetetaacetic acid (EDTA).

Erosive Potential of 1% Phytic Acid on Radicular Dentine at Different Time Intervals.

 The main aim of this study was to determine the undergraduate dental students' self-reported effectiveness of online classes offered by various dental institutes of Pakistan.

Self-Reported Effectiveness of e-Learning Classes during COVID-19 Pandemic: A Nation-Wide Survey of Pakistani Undergraduate Dentistry Students.

The purpose of this study was to observe the release of vascular endothelial growth factor (VEGF) after conditioning with etidronic acid (also known as 1-hydroxyethylidene-1 and 1-bisphosphonate [HEDP]) and phytic acid (inositol hexakisphosphate [IP6]) in comparison with EDTA on human dentin disks and cylinders.

Effect of Natural and Artificial Dentin Conditioners on the Release of Vascular Endothelial Growth Factor.

Preparation of root canal according to its desired anatomy and complete disinfection is a laborious task. Several factors influence the endodontic treatment including operator's skill and knowledge, anatomy of the tooth, the instruments and equipment used. In the past stainless-steel instruments were used to prepare the root canal but it causes many iatrogenic errors. Nickel titanium instruments evolved to overcome the iatrogenic damages caused by stainless steel instruments. Keeping this in mind a comparative study was conducted on the clinical work of dental intern using stainless steel files and progressively taper nickel titanium instruments. The objective of this study was to compare the performance of interns using either stainless Steel or progressively tapered hand operated NiTi instruments.

Outcome Of Endodontic Procedures Performed By Dental Interns Using Stainless Steel And Niti Files: A 10- Year Retrospective Study.

This in vivo animal study aimed to develop a murine model of pulpitis induced by pulp exposure with or without application of zymosan in Naval Medical Research Institute (NMRI) mice and observe expressions of Toll-like receptor (TLR)-2, TLR-4, Dectin-1, Osteopontin (OPN), tumor necrosis factor alpha (TNF-α), interleukin (IL)-6, and IL-1ß.

Expression of Toll-like receptor 2, Dectin-1, and Osteopontin in murine model of pulpitis.

Candida albicans is linked to persistent endodontic lesions. However, the recognition receptor that identifies it is not explored previously.

A novel experimental model to investigate fungal involvement shows expression of Dectin-1 in periapical lesion pathogenesis.

Luxation is a common traumatic dental injury treated with a wire composite (WC) splint. However, bulk-fill flowable composite and conventional packable composite have not been compared for retaining these splints. Therefore, the objectives of this randomized controlled trial were (1) to compare retention of WC splints, and (2) to compare adhesive point dimension, application and removal time, and effect on tooth mobility between the two WC splints.

Article	Year
Deciphering Possible Association of Risk Factors for Dental Caries in Pakistani Population. International journal of dentistry\| PubMed ID: 29681939	2018
Combined Endodontic and Surgical Management of Twin Rooted Maxillary Lateral Incisor with a Palatogingival Groove. Iranian endodontic journal\| PubMed ID: 30083218	2018
Erosive Potential of 1% Phytic Acid on Radicular Dentine at Different Time Intervals. European endodontic journal\| PubMed ID: 32342035	2020
Self-Reported Effectiveness of e-Learning Classes during COVID-19 Pandemic: A Nation-Wide Survey of Pakistani Undergraduate Dentistry Students. European journal of dentistry\| PubMed ID: 33003240	2020
Effect of Natural and Artificial Dentin Conditioners on the Release of Vascular Endothelial Growth Factor. Journal of endodontics\| PubMed ID: 33581196	2021
Outcome Of Endodontic Procedures Performed By Dental Interns Using Stainless Steel And Niti Files: A 10- Year Retrospective Study. Journal of Ayub Medical College, Abbottabad : JAMC\| PubMed ID: 35124913	2021
Expression of Toll-like receptor 2, Dectin-1, and Osteopontin in murine model of pulpitis. Clinical oral investigations\| PubMed ID: 36205788	2023
A novel experimental model to investigate fungal involvement shows expression of Dectin-1 in periapical lesion pathogenesis. Journal of oral rehabilitation\| PubMed ID: 37263973	2023
Comparison of two composite resin materials for splinting of dental luxation injuries: A double blind randomized controlled trial. Dental traumatology : official publication of International Association for Dental Traumatology\| PubMed ID: 37615239	2024

Javeria Ali Khan

Biography

JoVE Journal Publications

Other Publications