animal-models-for-long-term-functional-recovery-rehabilitation-after

Animal Models for Long-Term Functional Recovery and Rehabilitation After Ischemic Stroke: Beyond Acute Neuroprotection

Ischemic stroke is one of the leading causes of long-term disability worldwide. Although acute neuroprotection strategies have been extensively studied, ...

Weifang Hospital of Traditional Chinese Medicine, Shandong Second Medical University

Thalamic ataxia syndrome is a rare but severely disabling condition resulting from thalamic lesions, characterized by persistent motor incoordination that frequently fails to respond to conventional rehabilitation therapies. Given the lack of effective treatment options and the profound impact on patients' quality of life, this study aimed to evaluate the efficacy of local botulinum toxin type A (BoNT-A) injections as a potential breakthrough treatment for improving motor control and daily living activities in patients with thalamic ataxia. This investigation represents the first clinical application of BoNT-A specifically targeting thalamic ataxia, offering new hope for treatment-resistant cases.

Local injection of botulinum toxin type A in the treatment of thalamic ataxia syndrome: A case report.

Amyloid cardiomyopathy (AC) is a rare and fatal condition, often with a delayed diagnosis due to its nonspecific initial presentations. This case underscores the diagnostic challenge and critical importance of early recognition when patients present with seemingly unrelated gastrointestinal symptoms.

Article	Year
Local injection of botulinum toxin type A in the treatment of thalamic ataxia syndrome: A case report. Medicine\| PubMed ID: 40660583	2025
Amyloid cardiomyopathy presenting with gastrointestinal symptoms of abdominal pain, back pain, and constipation: A case report. Medicine\| PubMed ID: 41054135	2025

Manli Zhao

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