Luay Almassalha

Department of Biomedical Engineering, Northwestern University

Affiliated withNorthwestern University Northwestern Memorial Hospital

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2026
Publication title	2026

Other Publications

Article	Year
Colocalization of cellular nanostructure using confocal fluorescence and partial wave spectroscopy. Journal of biophotonics\| PubMed ID: 27111884	2017
Super-resolution spectroscopic microscopy via photon localization. Nature communications\| PubMed ID: 27452975	2016
Superresolution intrinsic fluorescence imaging of chromatin utilizing native, unmodified nucleic acids for contrast. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27535934	2016
Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 27549371	2016
The Greater Genomic Landscape: The Heterogeneous Evolution of Cancer. Cancer research\| PubMed ID: 27550448	2016
Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27702891	2016
The effects of chemical fixation on the cellular nanostructure. Experimental cell research\| PubMed ID: 28673821	2017
The transformation of the nuclear nanoarchitecture in human field carcinogenesis. Future science OA\| PubMed ID: 28884003	2017
Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins. Molecular biology of the cell\| PubMed ID: 29142071	2018
Macrogenomic engineering via modulation of the scaling of chromatin packing density. Nature biomedical engineering\| PubMed ID: 29450107	2017
Measuring Nanoscale Chromatin Heterogeneity with Partial Wave Spectroscopic Microscopy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29476478	2018
Correlating colorectal cancer risk with field carcinogenesis progression using partial wave spectroscopic microscopy. Cancer medicine\| PubMed ID: 29573208	2018
Label free localization of nanoparticles in live cancer cells using spectroscopic microscopy. Nanoscale\| PubMed ID: 30298892	2018
Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging. Light, science & applications\| PubMed ID: 30651982	2019
Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm. Nature communications\| PubMed ID: 30971691	2019
Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation. Molecular biology of the cell\| PubMed ID: 31216230	2019
Preservation of cellular nano-architecture by the process of chemical fixation for nanopathology. PloS one\| PubMed ID: 31329606	2019
Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation. Molecular biology of the cell\| PubMed ID: 31365328	2019
Dynamic Crowding Regulates Transcription. Biophysical journal\| PubMed ID: 31818468	2020
Disordered chromatin packing regulates phenotypic plasticity. Science advances\| PubMed ID: 31934628	2020
Physical and data structure of 3D genome. Science advances\| PubMed ID: 31950084	2020
Nanoscale chromatin imaging and analysis platform bridges 4D chromatin organization with molecular function. Science advances\| PubMed ID: 33523864	2021
Analysis of three-dimensional chromatin packing domains by chromatin scanning transmission electron microscopy (ChromSTEM). Scientific reports\| PubMed ID: 35842472	2022
Author Correction: Analysis of three-dimensional chromatin packing domains by chromatin scanning transmission electron microscopy (ChromSTEM). Scientific reports\| PubMed ID: 35882912	2022
Editorial: cooking up something new for diet therapy of eosinophilic oesophagitis. Alimentary pharmacology & therapeutics\| PubMed ID: 36071014	2022
Differentiation-dependent chromosomal organization changes in normal myogenic cells are absent in rhabdomyosarcoma cells. bioRxiv : the preprint server for biology\| PubMed ID: 37214969	2023
Correction: Label free localization of nanoparticles in live cancer cells using spectroscopic microscopy. Nanoscale\| PubMed ID: 37435809	2023
Local Volume Concentration, Packing Domains and Scaling Properties of Chromatin. Research square\| PubMed ID: 37886531	2023
Differentiation-dependent chromosomal organization changes in normal myogenic cells are absent in rhabdomyosarcoma cells. Frontiers in cell and developmental biology\| PubMed ID: 38020905	2023
DNA density is a better indicator of a nuclear bleb than lamin B loss. bioRxiv : the preprint server for biology\| PubMed ID: 38370828	2024
Local Volume Concentration, Packing Domains and Scaling Properties of Chromatin. ArXiv\| PubMed ID: 38495560	2024
Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism. Genome biology\| PubMed ID: 38519987	2024
Active transcription and epigenetic reactions synergistically regulate meso-scale genomic organization. Nature communications\| PubMed ID: 38773126	2024
Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure. PloS one\| PubMed ID: 38805476	2024
Local volume concentration, packing domains, and scaling properties of chromatin. eLife\| PubMed ID: 39331520	2024
Decreased DNA density is a better indicator of a nuclear bleb than lamin B loss. Journal of cell science\| PubMed ID: 39501901	2025
Leveraging chromatin packing domains to target chemoevasion . bioRxiv : the preprint server for biology\| PubMed ID: 39605341	2024
Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system. Science advances\| PubMed ID: 39792661	2025
Mature chromatin packing domains persist after RAD21 depletion in 3D. Science advances\| PubMed ID: 39854464	2025
Nuclear blebs are associated with destabilized chromatin-packing domains. Journal of cell science\| PubMed ID: 39878045	2025
Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 40051293	2025
Brewing up physician-scientists: An issue of percolation. Med (New York, N.Y.)\| PubMed ID: 40088882	2025
Three-color single-molecule localization microscopy in chromatin. Light, science & applications\| PubMed ID: 40091134	2025
Geometrically encoded positioning of introns, intergenic segments, and exons in the human genome. bioRxiv : the preprint server for biology\| PubMed ID: 40501616	2025
Over-The-Scope Clip Misdeployment Resulting in Acute Cholangitis and Biliary Pancreatitis. ACG case reports journal\| PubMed ID: 40666022	2025
Leveraging chromatin packing domains to target chemoevasion in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 40694328	2025
Multiplexed Chromatin Analysis Using Optical Spectroscopic Statistical Nanosensing. ACS photonics\| PubMed ID: 40718523	2025
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 41144753	2026
Chromatin architecture and physical constriction cooperate in phenotype switching and cancer cell dissemination. bioRxiv : the preprint server for biology\| PubMed ID: 41676741	2026