dose-response-threshold-effects-c-reactive-proteintriglycerideglucose

Dose-Response And Threshold Effects of a C-reactive Protein&#8211;Triglyceride&#8211;Glucose Composite Index and Endometriosis Risk: A Cross-Sectional Study

Endometriosis is a prevalent gynecological disorder associated with chronic low-grade inflammation, yet diagnosis is often delayed because symptoms are ...

Binhai County People's Hospital

Jiangsu Vocational College of Medicine

Increasing reports demonstrate that long noncoding RNAs participate in the regulation of numerous malignancies, cervical cancer included. Although lncRNA LOXL1 antisense RNA 1 has been commonly accepted to be an oncogene in many cancers. Here, the role of LOXL1-AS1 in CC still need to be explored. In this study, LOXL1-AS1 was found elevated in CC tissues and cells. LOXL1-AS1 depletion restrained CC cell proliferation, migration, invasion, and angiogenesis in vivo. Furthermore, we found that LOXL1-AS1 upregulated Lysophospholipase 1 expression via sequestering miR-526b-5p. Rescue assays revealed that overexpression of LYPLA1 reversed the LOXL1-AS1 silencing-induced inhibitory effects on the malignant phenotypes of CC cells. To conclude, this study showed that LOXL1-AS1 facilitates cellular process in CC via functioning as a miR-526b-5p sponge.

LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis.

Cervical cancer (CC), as a serious menace to the health of women, has long been one of the most lethal gynecologic neoplasms throughout the world. Long non-coding RNA (LncRNA)  has been documented to exert crucial functions in many malignant tumors. Nonetheless, the function and molecular mechanism of  in CC remain completely unknown.

LncRNA NR2F1-AS1 Inhibits the Malignant Properties of Cervical Cancer Cells via Targeting miR-642a-3p/NR2F1 Axis.

Correction: LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis.

Pelvic masses frequently originate from the pelvic cavity and are often associated with uterine, ovarian, or intestinal disorders. This report describes the case of a patient with a pelvic mass diagnosed as a retroperitoneal dermoid cyst at our hospital. We analyzed this case and conducted a literature review, to mitigate the risk of misdiagnosis and enhance the treatment of retroperitoneal masses.

Retroperitoneal dermoid cyst complicated with uterine adenomyoma: a case report and literature review.

To evaluate the impact of surgical compliance on overall survival (OS) and cancer-specific survival (CSS) in ovarian cancer patients and identify factors influencing surgical compliance.

Impact of surgical compliance on survival prognosis of patients with ovarian cancer and associated influencing factors: A propensity score matching analysis of the SEER database.

Uterine perforation with intravesical migration is an exceedingly rare complication of intrauterine device (IUD) use. Its non-specific symptomatology often leads to delayed diagnosis, while the presence of a uterine scar, such as from a prior cesarean section, may significantly increase the risk.

Article	Year
LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis. Biochemical genetics\| PubMed ID: 34984578	2022
LncRNA NR2F1-AS1 Inhibits the Malignant Properties of Cervical Cancer Cells via Targeting miR-642a-3p/NR2F1 Axis. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion\| PubMed ID: 36087939	2022
Correction: LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis. Biochemical genetics\| PubMed ID: 36352082	2023
Retroperitoneal dermoid cyst complicated with uterine adenomyoma: a case report and literature review. The Journal of international medical research\| PubMed ID: 38886867	2024
Impact of surgical compliance on survival prognosis of patients with ovarian cancer and associated influencing factors: A propensity score matching analysis of the SEER database. Heliyon\| PubMed ID: 39040330	2024
Cystoscopic retrieval of a migrated IUD with bladder stone formation during pregnancy termination: a Case Report. Frontiers in medicine\| PubMed ID: 41601760	2025

Lingyan Zhang

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