Sophie X. Deng

Cornea Division, University of California Los Angeles

Affiliated withUniversity of California Los Angeles

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Microbiology Profiles and Antibiotic Susceptibility in Pediatric Microbial Keratitis. Cornea\| PubMed ID: 39655769	2024
Preferential gene expression in the limbus of the vervet monkey. Molecular vision\| PubMed ID: 18989386	2008
SSEA4 is a potential negative marker for the enrichment of human corneal epithelial stem/progenitor cells. Investigative ophthalmology & visual science\| PubMed ID: 21685344	2011
Keratin 13 is a more specific marker of conjunctival epithelium than keratin 19. Molecular vision\| PubMed ID: 21738394	2011
Limbal lacuna: a novel limbal structure detected by in vivo laser scanning confocal microscopy. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 22150603	2011
Characterization of limbal stem cell deficiency by in vivo laser scanning confocal microscopy: a microstructural approach. Archives of ophthalmology (Chicago, Ill. : 1960)\| PubMed ID: 22159172	2012
In vivo confocal microscopic findings in Lisch corneal dystrophy. Cornea\| PubMed ID: 22222997	2012
Role of CTCF in EGF-induced migration of immortalized human corneal epithelial cells. Investigative ophthalmology & visual science\| PubMed ID: 22247490	2012
Preferential biological processes in the human limbus by differential gene profiling. PloS one\| PubMed ID: 23630617	2013
Presence of native limbal stromal cells increases the expansion efficiency of limbal stem/progenitor cells in culture. Experimental eye research\| PubMed ID: 24016868	2013
A three-dimensional culture method to expand limbal stem/progenitor cells. Tissue engineering. Part C, Methods\| PubMed ID: 24047104	2014
Frizzled 7 maintains the undifferentiated state of human limbal stem/progenitor cells. Stem cells (Dayton, Ohio)\| PubMed ID: 24170316	2014
Schlemm's canal expands after trabeculectomy in patients with primary angle-closure glaucoma. Investigative ophthalmology & visual science\| PubMed ID: 25118266	2014
Expression of the HSF4 DNA binding domain-EGFP hybrid gene recreates early childhood lamellar cataract in transgenic mice. Investigative ophthalmology & visual science\| PubMed ID: 25168898	2014
Human limbal mesenchymal cells support the growth of human corneal epithelial stem/progenitor cells. Investigative ophthalmology & visual science\| PubMed ID: 25277234	2014
Assessment of corneal epithelial thickness in dry eye patients. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 25279779	2014
Pseudomonas aeruginosa keratitis misdiagnosed as fungal keratitis by in vivo confocal microscopy: a case report. BMC research notes\| PubMed ID: 25495791	2014
Topical interferon alpha-2b for treatment of noninvasive ocular surface squamous neoplasia with 360° limbal involvement. Journal of ophthalmic & vision research\| PubMed ID: 25709765	2014
Combined astigmatic keratotomy and conductive keratoplasty to correct high corneal astigmatism. Journal of cataract and refractive surgery\| PubMed ID: 25935339	2015
Limbal Basal Cell Density Decreases in Limbal Stem Cell Deficiency. American journal of ophthalmology\| PubMed ID: 26149968	2015
Advances in the Diagnosis and Management of Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 39729420	2025
THz and mm-Wave Sensing of Corneal Tissue Water Content: Sensing and Imaging Results. IEEE transactions on terahertz science and technology\| PubMed ID: 26161292	2015
Epithelial Thinning in Limbal Stem Cell Deficiency. American journal of ophthalmology\| PubMed ID: 26163009	2015
Identification of presumed pathogenic KRT3 and KRT12 gene mutations associated with Meesmann corneal dystrophy. Molecular vision\| PubMed ID: 26788030	2015
A 3D culture system enhances the ability of human bone marrow stromal cells to support the growth of limbal stem/progenitor cells. Stem cell research\| PubMed ID: 26896856	2016
Existence of Normal Limbal Epithelium in Eyes With Clinical Signs of Total Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 27362882	2016
Correlation between the existence of the palisades of Vogt and limbal epithelial thickness in limbal stem cell deficiency. Clinical & experimental ophthalmology\| PubMed ID: 27591548	2017
Outcomes of Descemet Membrane Endothelial Keratoplasty in Patients With Previous Glaucoma Surgery. Cornea\| PubMed ID: 27893525	2017
Characterization of the Corneal Subbasal Nerve Plexus in Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 27941384	2017
Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells. Tissue engineering. Part C, Methods\| PubMed ID: 28346794	2017
Genome-wide analysis suggests a differential microRNA signature associated with normal and diabetic human corneal limbus. Scientific reports\| PubMed ID: 28615632	2017
Human adipose-derived stem cells support the growth of limbal stem/progenitor cells. PloS one\| PubMed ID: 29020119	2017
The diagnosis of limbal stem cell deficiency. The ocular surface\| PubMed ID: 29113917	2018
A Case of Corneal Neovascularization Misdiagnosed as Total Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 29781927	2018
In Vivo Evaluation of the Limbus Using Anterior Segment Optical Coherence Tomography. Translational vision science & technology\| PubMed ID: 30112250	2018
Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading. Cornea\| PubMed ID: 30371569	2019
Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 30614902	2019
The application of human amniotic membrane in the surgical management of limbal stem cell deficiency. The ocular surface\| PubMed ID: 30633967	2019
Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro. Investigative ophthalmology & visual science\| PubMed ID: 30640975	2019
Comparison of Endothelial Keratoplasty Techniques in Patients With Prior Glaucoma Surgery: A Case-Matched Study. American journal of ophthalmology\| PubMed ID: 30935848	2019
Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis. Survey of ophthalmology\| PubMed ID: 31276736	2020
Mesenchymal Stem Cells Reduce Corneal Fibrosis and Inflammation via Extracellular Vesicle-Mediated Delivery of miRNA. Stem cells translational medicine\| PubMed ID: 31290598	2019
Differentiation Capacity of Human Mesenchymal Stem Cells into Keratocyte Lineage. Investigative ophthalmology & visual science\| PubMed ID: 31310658	2019
Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro. Scientific reports\| PubMed ID: 31316119	2019
Limbal Stem Cell Deficiency After Glaucoma Surgery. Cornea\| PubMed ID: 31977730	2020
Corneal Epithelial Thickness Measured Using Anterior Segment Optical Coherence Tomography as a Diagnostic Parameter for Limbal Stem Cell Deficiency. American journal of ophthalmology\| PubMed ID: 32283095	2020
Outcomes of Limbal Stem Cell Transplant: A Meta-analysis. JAMA ophthalmology\| PubMed ID: 32324211	2020
A Small-Molecule Wnt Mimic Improves Human Limbal Stem Cell Ex Vivo Expansion. iScience\| PubMed ID: 32361505	2020
Long-Term Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes with Prior Glaucoma Surgery. American journal of ophthalmology\| PubMed ID: 32619607	2020
Role of Jagged1-mediated Notch Signaling Activation in the Differentiation and Stratification of the Human Limbal Epithelium. Cells\| PubMed ID: 32842657	2020
Expansion of Human Limbal Epithelial Stem/Progenitor Cells Using Different Human Sera: A Multivariate Statistical Analysis. International journal of molecular sciences\| PubMed ID: 32854428	2020
Reply to Comment on: Corneal Epithelial Thickness Measured Using AS-OCT as a Diagnostic Parameter for Limbal Stem Cell Deficiency. American journal of ophthalmology\| PubMed ID: 32896370	2020
Sutured Custom Foldable Silicone Artificial Iris Implantation Combined With Intraocular Lens Implantation and Penetrating Keratoplasty: Safety and Efficacy Outcomes. Cornea\| PubMed ID: 33086281	2021
Therapeutic Potential of Extracellular Vesicles for the Treatment of Corneal Injuries and Scars. Translational vision science & technology\| PubMed ID: 33200043	2020
Limbal stem cell diseases. Experimental eye research\| PubMed ID: 33571530	2021
Human limbal epithelial stem cell regulation, bioengineering and function. Progress in retinal and eye research\| PubMed ID: 33676006	2021
Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. Biofabrication\| PubMed ID: 34330126	2021
Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine. RSC chemical biology\| PubMed ID: 34458828	2021
Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells. Scientific reports\| PubMed ID: 34686698	2021
Clinical outcomes and complications of fluid-filled scleral lens devices for the management of limbal stem cell deficiency. Contact lens & anterior eye : the journal of the British Contact Lens Association\| PubMed ID: 34728142	2023
Cytokeratin 13 Is a New Biomarker for the Diagnosis of Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 34743102	2022
Regulation of Limbal Epithelial Stem Cells: Importance of the Niche. International journal of molecular sciences\| PubMed ID: 34769405	2021
Biomarkers of in vivo limbal stem cell function. The ocular surface\| PubMed ID: 34902592	2022
Cell Morphology as an In Vivo Parameter for the Diagnosis of Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 34935665	2022
Rapid 3D bioprinting of a multicellular model recapitulating pterygium microenvironment. Biomaterials\| PubMed ID: 35101743	2022
R-etodolac is a more potent Wnt signaling inhibitor than enantiomer, S-etodolac. Biochemistry and biophysics reports\| PubMed ID: 35243012	2022
Comment on: Long-Term Outcome After Superficial Keratectomy of the Abnormal Epithelium for Partial Limbal Stem Cell Deficiency. American journal of ophthalmology\| PubMed ID: 35296409	2022
Extracellular miR-6723-5p could serve as a biomarker of limbal epithelial stem/progenitor cell population. Biomarker research\| PubMed ID: 35642012	2022
650 GHz imaging as alignment verification for millimeter wave corneal reflectometry. IEEE transactions on terahertz science and technology\| PubMed ID: 36185397	2022
Autologous Serum Eye Drops in the Management of Limbal Stem Cell Deficiency Associated With Glaucoma Surgery. Eye & contact lens\| PubMed ID: 36322388	2023
Generation of Functional Immortalized Human Corneal Stromal Stem Cells. International journal of molecular sciences\| PubMed ID: 36362184	2022
Stability and Function of Extracellular Vesicles Derived from Immortalized Human Corneal Stromal Stem Cells: A Proof of Concept Study. The AAPS journal\| PubMed ID: 36471035	2022
Single mRNA detection of Wnt signaling pathway in the human limbus. Experimental eye research\| PubMed ID: 36702232	2023
Descemet membrane endothelial keratoplasty in eyes with glaucoma. Taiwan journal of ophthalmology\| PubMed ID: 37252169	2023
Ocular Surface Regeneration by Limbal Stem Cells Therapies: State of the Art, Challenges, and Perspectives. Stem cells translational medicine\| PubMed ID: 37715946	2023
Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency. Scientific reports\| PubMed ID: 37735479	2023
Latent diffusion augmentation enhances deep learning analysis of neuro-morphology in limbal stem cell deficiency. Frontiers in medicine\| PubMed ID: 37908848	2023
Three-Dimensional Reconstruction of Subbasal Nerve Density in Eyes With Limbal Stem Cell Deficiency: A Pilot Study. Cornea\| PubMed ID: 38923539	2024
Co-existence of Neurotrophic Keratopathy in Eyes With Limbal Stem Cell Deficiency. American journal of ophthalmology\| PubMed ID: 38945348	2024
Positive cooperativity in synergistic activation of Wnt proteins. Molecular biology reports\| PubMed ID: 39154310	2024
Comparison of Automated and Manual Measurement of Corneal Epithelial Thickness in Eyes With Limbal Stem Cell Deficiency. Cornea\| PubMed ID: 39196902	2025
Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork. Translational vision science & technology\| PubMed ID: 39847376	2025
On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. Biosensors\| PubMed ID: 40136938	2025
Predictors of Post-treatment Visual Improvement After Bacterial Keratitis Infection at a Referral Center in Southern California. Cornea\| PubMed ID: 40920988	2025
Outcome of Cenegermin in the Treatment of Neurotrophic Keratopathy. Cornea\| PubMed ID: 41247282	2025
Limbal Epithelial Cells Detected in Stage III Limbal Stem Cell Deficiency by Multimodal Anterior Segment Imaging. American journal of ophthalmology\| PubMed ID: 41338407	2026
Automated Image Registration Method for In Vivo Confocal Microscopy of the Corneal Sub-basal Nerve Plexus. AMIA ... Annual Symposium proceedings. AMIA Symposium\| PubMed ID: 41726503	2024