Motoko Takahashi

Department of Biochemistry, Sapporo Medical University School of Medicine

Affiliated withSapporo Medical University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Pulmonary collectins in innate immunity of the lung. Cellular microbiology\| PubMed ID: 17490408	2007
N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion. Biochimica et biophysica acta\| PubMed ID: 18036567	2008
Pulmonary surfactant protein D inhibits lipopolysaccharide (LPS)-induced inflammatory cell responses by altering LPS binding to its receptors. The Journal of biological chemistry\| PubMed ID: 18990700	2008
Pulmonary surfactant protein D binds MD-2 through the carbohydrate recognition domain. Biochemistry\| PubMed ID: 18991397	2008
Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: their functions and target proteins. Carbohydrate research\| PubMed ID: 19508951	2009
Mutational analysis of Cys(88) of Toll-like receptor 4 highlights the critical role of MD-2 in cell surface receptor expression. International immunology\| PubMed ID: 19556306	2009
Mannose binding lectin and lung collectins interact with Toll-like receptor 4 and MD-2 by different mechanisms. Biochimica et biophysica acta\| PubMed ID: 19840833	2009
Pulmonary collectins protect macrophages against pore-forming activity of Legionella pneumophila and suppress its intracellular growth. The Journal of biological chemistry\| PubMed ID: 20056602	2010
[Importance of core fucose in receptor function]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme\| PubMed ID: 21089356	2008
Pulmonary collectins play distinct roles in host defense against Mycobacterium avium. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21821801	2011
Pulmonary surfactant protein A protects lung epithelium from cytotoxicity of human β-defensin 3. The Journal of biological chemistry\| PubMed ID: 22418431	2012
In vivo role of aldehyde reductase. Biochimica et biophysica acta\| PubMed ID: 22820017	2012
Detection of N-glycolyated gangliosides in non-small-cell lung cancer using GMR8 monoclonal antibody. Cancer science\| PubMed ID: 23004020	2013
Surfactant protein D inhibits adherence of uropathogenic Escherichia coli to the bladder epithelial cells and the bacterium-induced cytotoxicity: a possible function in urinary tract. The Journal of biological chemistry\| PubMed ID: 23012359	2012
Suppression of heregulin β signaling by the single N-glycan deletion mutant of soluble ErbB3 protein. The Journal of biological chemistry\| PubMed ID: 24097984	2013
Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice. Life sciences\| PubMed ID: 24355294	2014
The effects of exercise training on obesity-induced dysregulated expression of adipokines in white adipose tissue. International journal of endocrinology\| PubMed ID: 24369466	2013
Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals. Biochemical and biophysical research communications\| PubMed ID: 25152401	2014
The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin β1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway. Biochemical and biophysical research communications\| PubMed ID: 25451255	2014
Fucosylated surfactant protein-D is a biomarker candidate for the development of chronic obstructive pulmonary disease. Journal of proteomics\| PubMed ID: 26206179	2015
Proteomic and glycomic analyses of a lung-specific protein surfactant protein-D. Data in brief\| PubMed ID: 26958622	2015
Disease-associated glycans on cell surface proteins. Molecular aspects of medicine\| PubMed ID: 27131428	2016
Glycation vs. glycosylation: a tale of two different chemistries and biology in Alzheimer's disease. Glycoconjugate journal\| PubMed ID: 27325408	2016
N-glycans of growth factor receptors: their role in receptor function and disease implications. Clinical science (London, England : 1979)\| PubMed ID: 27612953	2016
Surfactant protein A (SP-A) and SP-A-derived peptide attenuate chemotaxis of mast cells induced by human β-defensin 3. Biochemical and biophysical research communications\| PubMed ID: 28188794	2017
Surfactant Protein A Inhibits Growth and Adherence of Uropathogenic To Protect the Bladder from Infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28228557	2017
Disruption of the structural and functional features of surfactant protein A by acrolein in cigarette smoke. Scientific reports\| PubMed ID: 28814727	2017
Surfactant protein A down-regulates epidermal growth factor receptor by mechanisms different from those of surfactant protein D. The Journal of biological chemistry\| PubMed ID: 28972165	2017
Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis. Respiratory research\| PubMed ID: 29486761	2018
Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury. Toxicology letters\| PubMed ID: 29763686	2018
Comparison of immune response in mice sensitized to an animal allergen, Can f 1, and to a food allergen, ovalbumin. Biomedical research (Tokyo, Japan)\| PubMed ID: 30787264	2019
Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction. Scientific reports\| PubMed ID: 31611630	2019
Insufficient serum L-ficolin is associated with disease presence and extent of pulmonary Mycobacterium avium complex disease. Respiratory research\| PubMed ID: 31638993	2019
Acrolein in cigarette smoke attenuates the innate immune responses mediated by surfactant protein D. Biochimica et biophysica acta. General subjects\| PubMed ID: 32738274	2020
Retraction Note: Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction. Scientific reports\| PubMed ID: 33214671	2020
Treatment of air leakage using the VIO soft coagulation system: a mouse pulmonary air leak model. Surgery today\| PubMed ID: 33743052	2021
Maillard reaction in vivo and its relevance to diseases: editorial and dedication. Glycoconjugate journal\| PubMed ID: 33893942	2021
Integrated Structural Analysis of -Glycans and Free Oligosaccharides Allows for a Quantitative Evaluation of ER Stress. Biochemistry\| PubMed ID: 33983715	2021
Pleiotropic Actions of Aldehyde Reductase (AKR1A). Metabolites\| PubMed ID: 34073440	2021
Role of glycosyltransferases in carcinogenesis; growth factor signaling and EMT/MET programs. Glycoconjugate journal\| PubMed ID: 35089466	2022
N-glycosylation regulates MET processing and signaling. Cancer science\| PubMed ID: 35092134	2022
Junctional adhesion molecule 3 is a potential therapeutic target for small cell lung carcinoma. Experimental cell research\| PubMed ID: 36990421	2023
CINC-2 and miR-199a-5p in EVs secreted by transplanted Thy1 cells activate hepatocytic progenitor cell growth in rat liver regeneration. Stem cell research & therapy\| PubMed ID: 37194082	2023
Site-specific glycosylation analysis of epidermal growth factor receptor 2 (ErbB2): exploring structure and function toward therapeutic targeting. Glycobiology\| PubMed ID: 38109791	2024
N-glycan on N262 of FGFR3 regulates the intracellular localization and phosphorylation of the receptor. Biochimica et biophysica acta. General subjects\| PubMed ID: 38244702	2024
Roles of Glyco-Redox in Epithelial Mesenchymal Transition and Mesenchymal Epithelial Transition, Cancer, and Various Diseases. Antioxidants & redox signaling\| PubMed ID: 39345141	2024
Pentosidine accumulation induced by Akr1a deficiency drives aggression and hyperactivity. Neuroscience letters\| PubMed ID: 41730470	2026