preparation-neovascular-tissues-from-human-glioma-tissues-for

Preparation Of Neovascular Tissues from Human Glioma Tissues for Quantitative Proteomics Analysis of Tumor Angiogenesis

Glioma represents primary malignant tumors of the central nervous system with significant incidence and mortality. Tumor angiogenesis is the hallmark of ...

Shandong First Medical University & Shandong Academy of Medical Science

The proteasome is a crucial mechanism that regulates protein fate and eliminates misfolded proteins, playing a significant role in cellular processes. In the context of lung cancer, the proteasome's regulatory function is closely associated with the disease's pathophysiology, revealing multiple connections within the cell. Therefore, studying proteasome inhibitors as a means to identify potential pathways in carcinogenesis and metastatic progression is crucial in in-depth insight into its molecular mechanism and discovery of new therapeutic target to improve its therapy, and establishing effective biomarkers for patient stratification, predictive diagnosis, prognostic assessment, and personalized treatment for lung squamous carcinoma in the framework of predictive, preventive, and personalized medicine (PPPM; 3P medicine).

Clinically relevant stratification of lung squamous carcinoma patients based on ubiquitinated proteasome genes for 3P medical approach.

Hypertension, a major modifiable risk factor for cardiovascular disease, exhibits significant heterogeneity due to genetic, metabolic, and environmental influences. Traditional one-size-fits-all management is inadequate, necessitating predictive, preventive, and personalized medicine (3PM) approaches.

Article	Year
Clinically relevant stratification of lung squamous carcinoma patients based on ubiquitinated proteasome genes for 3P medical approach. The EPMA journal\| PubMed ID: 38463626	2024
The use of predictive, preventive, and personalized medical approaches to optimize hypertension management. The EPMA journal\| PubMed ID: 41311994	2025

Xiaoxia Feng

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