Irene H. Heijink

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen

Affiliated withUniversity of Groningen, University Medical Center Groningen University Medical Center Groningen, University of Groningen

Research Area

Bioengineering

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease. Thorax\| PubMed ID: 23370438	2013
Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity. Thorax\| PubMed ID: 23925644	2014
Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells. Respiratory research\| PubMed ID: 24088173	2013
Glucocorticoids induce the production of the chemoattractant CCL20 in airway epithelium. The European respiratory journal\| PubMed ID: 24627531	2014
A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 25637608	2015
Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 26320152	2015
Budesonide and fluticasone propionate differentially affect the airway epithelial barrier. Respiratory research\| PubMed ID: 26739349	2016
Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD. The European respiratory journal\| PubMed ID: 27126693	2016
Viral mimic poly-(I:C) attenuates airway epithelial T-cell suppressive capacity: implications for asthma. The European respiratory journal\| PubMed ID: 27824598	2016
Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress. PloS one\| PubMed ID: 28771582	2017
Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression. Respiratory research\| PubMed ID: 29268739	2017
Effects of fluticasone propionate and budesonide on the expression of immune defense genes in bronchial epithelial cells. Pulmonary pharmacology & therapeutics\| PubMed ID: 29627483	2018
Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology. Scientific reports\| PubMed ID: 30185803	2018
Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation. EBioMedicine\| PubMed ID: 30236449	2018
From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 "Basic and Translational Science.". ERJ open research\| PubMed ID: 31111040	2019
Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium. Scientific reports\| PubMed ID: 31636329	2019
Gene network approach reveals co-expression patterns in nasal and bronchial epithelium. Scientific reports\| PubMed ID: 31676779	2019
Mitochondria: at the crossroads of regulating lung epithelial cell function in chronic obstructive pulmonary disease. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 31693390	2020
A-Kinase Anchoring Proteins Diminish TGF-β/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition. Cells\| PubMed ID: 32028718	2020
ERS International Congress, Madrid, 2019: highlights from the Basic and Translational Science Assembly. ERJ open research\| PubMed ID: 32154289	2020
Epithelial-interleukin-1 inhibits collagen formation by airway fibroblasts: Implications for asthma. Scientific reports\| PubMed ID: 32457454	2020
miR-223: A Key Regulator in the Innate Immune Response in Asthma and COPD. Frontiers in medicine\| PubMed ID: 32509795	2020
Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD. Scientific reports\| PubMed ID: 33060632	2020
Effects of cigarette smoking on SARS-CoV-2 receptor ACE2 expression in the respiratory epithelium. The Journal of pathology\| PubMed ID: 33368245	2021
Macrophage-stroma interactions in fibrosis: biochemical, biophysical, and cellular perspectives. The Journal of pathology\| PubMed ID: 33506963	2021
Adipose Stromal Cell-Secretome Counteracts Profibrotic Signals From IPF Lung Matrices. Frontiers in pharmacology\| PubMed ID: 34393771	2021
Connecting GWAS Susceptibility Genes in COPD: Do We Need to Consider TGF-β2? American journal of respiratory cell and molecular biology\| PubMed ID: 34411507	2021
Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD. European respiratory review : an official journal of the European Respiratory Society\| PubMed ID: 35321933	2022
From Differential DNA Methylation in COPD to Mitochondria: Regulation of AHRR Expression Affects Airway Epithelial Response to Cigarette Smoke. Cells\| PubMed ID: 36359818	2022
Highway to : Influence of altered extracellular matrix on infiltrating immune cells during acute and chronic lung diseases. Frontiers in pharmacology\| PubMed ID: 36408219	2022
Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls. Respiratory research\| PubMed ID: 36681830	2023
ERS International Congress 2022: highlights from the Basic and Translational Science Assembly. ERJ open research\| PubMed ID: 37077558	2023
Host-device interactions: exposure of lung epithelial cells and fibroblasts to nickel, titanium, or nitinol affect proliferation, reactive oxygen species production, and cellular signaling. Journal of materials science. Materials in medicine\| PubMed ID: 37486435	2023
Dysregulated cross-talk between alveolar epithelial cells and stromal cells in idiopathic pulmonary fibrosis reduces epithelial regenerative capacity. Frontiers in medicine\| PubMed ID: 37621459	2023
ERS International Congress 2023: highlights from the Basic and Translational Sciences Assembly. ERJ open research\| PubMed ID: 38686182	2024
The importance of translational science within the respiratory field. Breathe (Sheffield, England)\| PubMed ID: 38746906	2024
Neutrophilic inflammation in sputum or blood does not define a clinically distinct asthma phenotype in ATLANTIS. ERJ open research\| PubMed ID: 39963164	2025
ERS Congress 2024: highlights from the Basic and Translational Sciences Assembly. ERJ open research\| PubMed ID: 40524928	2025
The Role of miR-320d in Regulation of Cigarette Smoke-Induced Pro-Inflammatory Responses in COPD. Archivos de bronconeumologia\| PubMed ID: 40707280	2026