Simon D. Pouwels

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen

Affiliated withUniversity of Groningen, University Medical Center Groningen University Medical Center Groningen, University of Groningen

Research Area

Bioengineering

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients. The European respiratory journal\| PubMed ID: 25931489	2015
The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux. Autophagy\| PubMed ID: 26086204	2015
Advanced glycation endproducts and their receptor in different body compartments in COPD. Respiratory research\| PubMed ID: 27117828	2016
Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 27612964	2016
Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 28596295	2017
Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release. Scientific reports\| PubMed ID: 30127367	2018
AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers. Respiratory research\| PubMed ID: 30971245	2019
Galectin-9 Is a Possible Promoter of Immunopathology in Rheumatoid Arthritis by Activation of Peptidyl Arginine Deiminase 4 (PAD-4) in Granulocytes. International journal of molecular sciences\| PubMed ID: 31430907	2019
Mitochondria: at the crossroads of regulating lung epithelial cell function in chronic obstructive pulmonary disease. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 31693390	2020
Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing. Pharmaceutics\| PubMed ID: 32344567	2020
Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases. Clinical science (London, England : 1979)\| PubMed ID: 33084883	2020
Effects of cigarette smoking on SARS-CoV-2 receptor ACE2 expression in the respiratory epithelium. The Journal of pathology\| PubMed ID: 33368245	2021
Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM. Cells\| PubMed ID: 34209854	2021
Airway granulation response to lung-implantable medical devices: a concise overview. European respiratory review : an official journal of the European Respiratory Society\| PubMed ID: 34348981	2021
The cellular composition of the lung lining fluid gradually changes from bronchus to alveolus. Respiratory research\| PubMed ID: 34736473	2021
Crosslink bio-adhesives for bronchoscopic lung volume reduction: current status and future direction. European respiratory review : an official journal of the European Respiratory Society\| PubMed ID: 34853096	2021
An Integrative Genomic Strategy Identifies Soluble Receptor for Advanced Glycation End-Products as a Causal and Protective Biomarker of Lung Function. Chest\| PubMed ID: 35000706	2022
Identification of damage associated molecular patterns and extracellular matrix proteins as major constituents of the surface proteome of lung implantable silicone/nitinol devices. Acta biomaterialia\| PubMed ID: 35038586	2022
Plasma sRAGE levels strongly associate with centrilobular emphysema assessed by HRCT scans. Respiratory research\| PubMed ID: 35073932	2022
The Decrease in Serum sRAGE Levels Upon Smoking is Associated with Activated Neutrophils. Lung\| PubMed ID: 36282357	2022
Highway to : Influence of altered extracellular matrix on infiltrating immune cells during acute and chronic lung diseases. Frontiers in pharmacology\| PubMed ID: 36408219	2022
Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts. Frontiers in pharmacology\| PubMed ID: 36408252	2022
Airway wall splice quantitative trait locus analysis reveals novel downstream mechanisms for known asthma single-nucleotide polymorphisms. ERJ open research\| PubMed ID: 37020836	2023
Smoking increases expression of the SARS-CoV-2 spike protein-binding long ACE2 isoform in bronchial epithelium. Respiratory research\| PubMed ID: 37170105	2023
Host-device interactions: exposure of lung epithelial cells and fibroblasts to nickel, titanium, or nitinol affect proliferation, reactive oxygen species production, and cellular signaling. Journal of materials science. Materials in medicine\| PubMed ID: 37486435	2023
COPD Patients Display Increased Peripheral Blood Somatic Mutations Which Associate With the Prevalence of Co-morbidities. Archivos de bronconeumologia\| PubMed ID: 38212182	2024
Low serum double-stranded DNA levels are associated with higher survival rates in severe COPD patients. ERJ open research\| PubMed ID: 39010886	2024
Identification of Genetic Factors Associated With DAMP Release in COPD Patients. Archivos de bronconeumologia\| PubMed ID: 39034199	2024
Neutrophilic inflammation in sputum or blood does not define a clinically distinct asthma phenotype in ATLANTIS. ERJ open research\| PubMed ID: 39963164	2025
Systemic pro-inflammatory response following bronchoscopic lung volume reduction using endobronchial valves. ERJ open research\| PubMed ID: 40071272	2025
Improving Complex Coacervate Tissue Adhesive Performance Using Bridging Polymer Chains. Biomacromolecules\| PubMed ID: 40129391	2025
Genome-Wide Differential Airway Gene Expression Analysis Identifies Genes Associated with COPD Comorbidities. Lung\| PubMed ID: 40287517	2025
Identification of Clinically Distinct Clusters in Patients With Severe COPD Using Circulating Blood Cell Population Parameters. Respirology (Carlton, Vic.)\| PubMed ID: 41111194	2026
Comorbidity profiles in chronic obstructive pulmonary disease: a multicohort study. ERJ open research\| PubMed ID: 41158484	2025
Complex coacervate tissue adhesives: effect of polycation chemistry and ionic strength on cytocompatibility. Journal of materials science. Materials in medicine\| PubMed ID: 41483295	2026