Xiong Guo

School of Public Health, Xi'an Jiaotong University Health Science Center

Affiliated withXi'an Jiaotong University Health Science Center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
[Comparison of the expression profiles of cell death factors in articular cartilage between Kashin-Beck disease and osteoarthritis]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University\| PubMed ID: 25537903	2014
Integrative meta-analysis of differentially expressed genes in osteoarthritis using microarray technology. Molecular medicine reports\| PubMed ID: 25975828	2015
Gene expression signature in endemic osteoarthritis by microarray analysis. International journal of molecular sciences\| PubMed ID: 25997002	2015
Diagnostic value of circulating microRNAs for osteosarcoma in Asian populations: a meta-analysis. Clinical and experimental medicine\| PubMed ID: 27106278	2017
Elevation of IGFBP2 contributes to mycotoxin T-2-induced chondrocyte injury and metabolism. Biochemical and biophysical research communications\| PubMed ID: 27416762	2016
Zinc: the Other Suspected Environmental Factor in Kashin-Beck Disease in Addition to Selenium. Biological trace element research\| PubMed ID: 28224461	2017
Roles of Glycoproteins in the Diagnosis and Differential Diagnosis of Chronic and Latent Keshan Disease. Molecules (Basel, Switzerland)\| PubMed ID: 28481304	2017
Serum and Hair Zinc Levels in Patients with Endemic Osteochondropathy in China: A Meta-analysis. Biological trace element research\| PubMed ID: 28567582	2018
Inflammatory cytokine of IL-1β is involved in T-2 toxin-triggered chondrocyte injury and metabolism imbalance by the activation of Wnt/β-catenin signaling. Molecular immunology\| PubMed ID: 28963928	2017
Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 29024729	2018
Chondrocytes damage induced by T-2 toxin via Wnt/β-catenin signaling pathway is involved in the pathogenesis of an endemic osteochondropathy, Kashin-Beck disease. Experimental cell research\| PubMed ID: 29042209	2017
Integrated bioinformatics analysis of the osteoarthritis‑associated microRNA expression signature. Molecular medicine reports\| PubMed ID: 29138855	2018
Imbalance of dietary nutrients and the associated differentially expressed genes and pathways may play important roles in juvenile Kashin-Beck disease. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)\| PubMed ID: 29426639	2018
Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis. Arthritis research & therapy\| PubMed ID: 29514696	2018
Dietary exosome-miR-23b may be a novel therapeutic measure for preventing Kashin-Beck disease. Experimental and therapeutic medicine\| PubMed ID: 29556257	2018
Integrative analysis of genome-wide association study and brain region related enhancer maps identifies biological pathways for insomnia. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 29883697	2018
eQTLs Weighted Genetic Correlation Analysis Detected Brain Region Differences in Genetic Correlations for Complex Psychiatric Disorders. Schizophrenia bulletin\| PubMed ID: 29912442	2019
The Importance of Se-Related Genes in the Chondrocyte of Kashin-Beck Disease Revealed by Whole Genomic Microarray and Network Analysis. Biological trace element research\| PubMed ID: 29948913	2019
The effects of T-2 toxin on the prevalence and development of Kashin-Beck disease in China: a meta-analysis and systematic review. Toxicology research\| PubMed ID: 30090385	2016
Comparison of bone texture between normal individuals and patients with Kashin-Beck disease from plain radiographs in knee. Scientific reports\| PubMed ID: 30504816	2018
Biological Analysis of Gene Expression and Clinical Variables Suggest FZD1 as a Novel Biomarker for Patients with Kashin-Beck Disease, an Endemic Osteoarthritis in China. Disease markers\| PubMed ID: 30719180	2019
The systematic review and meta-analysis of X-ray detective rate of Kashin-Beck disease from 1992 to 2016. BMC musculoskeletal disorders\| PubMed ID: 30764809	2019
Changes in the NF-κB signaling pathway in juvenile and adult patients with Kashin-Beck disease. Experimental cell research\| PubMed ID: 30951708	2019
Hair multi-bioelement profile of Kashin-Beck disease in the endemic regions of China. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)\| PubMed ID: 31109624	2019
The Functional Analysis of Selenium-Related Genes and Magnesium-Related Genes in the Gene Expression Profile Microarray in the Peripheral Blood Mononuclear Cells of Keshan Disease. Biological trace element research\| PubMed ID: 31165343	2019
Screening for Differentially Expressed Circular RNAs in the Cartilage of Osteoarthritis Patients for Their Diagnostic Value. Genetic testing and molecular biomarkers\| PubMed ID: 31502887	2019
Preliminary Exploration of hsa_circ_0032131 Levels in Peripheral Blood as a Potential Diagnostic Biomarker of Osteoarthritis. Genetic testing and molecular biomarkers\| PubMed ID: 31526191	2019
Screening for differentially expressed circRNA between Kashin-Beck disease and osteoarthritis patients based on circRNA chips. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 31678276	2020
Inhibiting the aberrant activation of Wnt/β-catenin signaling by selenium supplementation ameliorates deoxynivalenol-induced toxicity and catabolism in chondrocytes. Journal of cellular physiology\| PubMed ID: 31808557	2020
Abnormal expression of chondroitin sulfate sulfotransferases in the articular cartilage of pediatric patients with Kashin-Beck disease. Histochemistry and cell biology\| PubMed ID: 31845005	2020
Comparison of the responsiveness of the WOMAC and the 12-item WHODAS 2.0 in patients with Kashin-Beck disease. BMC musculoskeletal disorders\| PubMed ID: 32213176	2020
Genetic association scan of 32 osteoarthritis susceptibility genes identified TP63 associated with an endemic osteoarthritis, Kashin-Beck disease. Bone\| PubMed ID: 33964467	2021
Comparison of the major cell populations among osteoarthritis, Kashin-Beck disease and healthy chondrocytes by single-cell RNA-seq analysis. Cell death & disease\| PubMed ID: 34045450	2021
Effectiveness of Selenium on Chondrocyte Glycoprotein Glycosylation Which Play Important Roles in the Pathogenesis of an Endemic Osteoarthritis, Kashin-Beck Disease. Biological trace element research\| PubMed ID: 34165665	2022
Alterations in the gut microbiota and metabolite profiles of patients with Kashin-Beck disease, an endemic osteoarthritis in China. Cell death & disease\| PubMed ID: 34711812	2021
Polymorphism of MMP-3 gene and imbalance expression of MMP-3 / TIMP-1 in articular cartilage are associated with an endemic osteochondropathy, Kashin- Beck disease. BMC musculoskeletal disorders\| PubMed ID: 34980041	2022
Abnormal Level of Manganese, Iron, Iodine, and Selenium in the Hair of Children Living in Kashin-Beck Disease Endemic Areas. Biological trace element research\| PubMed ID: 34993910	2022
Correction to: Polymorphism of MMP-3 gene and imbalance expression of MMP-3 / TIMP-1 in articular cartilage are associated with an endemic osteochondropathy, Kashin- Beck disease. BMC musculoskeletal disorders\| PubMed ID: 35168577	2022
The Status of Selenium and Zinc in the Urine of Children From Endemic Areas of Kashin-Beck Disease Over Three Consecutive Years. Frontiers in nutrition\| PubMed ID: 35464016	2022
Investigation of selenium nutritional status and dietary pattern among children in Kashin-Beck disease endemic areas in Shaanxi Province, China using duplicate portion sampling method. Environment international\| PubMed ID: 35561595	2022
Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China. Arthritis research & therapy\| PubMed ID: 35637503	2022
Comprehensive comparative analysis of histopathology and gene expression in subchondral bone between kashin-beck disease and primary osteoarthritis. Frontiers in genetics\| PubMed ID: 35923709	2022
Abnormal expression of TSG-6 disturbs extracellular matrix homeostasis in chondrocytes from endemic osteoarthritis. Frontiers in genetics\| PubMed ID: 36468025	2022
The alteration of urinary metabolomics profiles in Kashin-Beck disease in a three consecutive year study. Molecular omics\| PubMed ID: 36508252	2023
Differential expression of cyclins CCNB1 and CCNG1 is involved in the chondrocyte damage of kashin-beck disease. Frontiers in genetics\| PubMed ID: 36588792	2022
Detection of selenoprotein transcriptome in chondrocytes of patients with Kashin-Beck disease. Frontiers in cell and developmental biology\| PubMed ID: 36875769	2023
Analysis of -glycosylation protein of Kashin-Beck disease chondrocytes derived from induced pluripotent stem cells based on label-free strategies with LC-MS/MS. Molecular omics\| PubMed ID: 37186116	2023
Correction: Analysis of -glycosylation protein of Kashin-Beck disease chondrocytes derived from induced pluripotent stem cells based on label-free strategies with LC-MS/MS. Molecular omics\| PubMed ID: 37222004	2023
Altered gut microbiome profile in patients with knee osteoarthritis. Frontiers in microbiology\| PubMed ID: 37250055	2023
Comparative Analysis of Differentially Expressed Genes in Chondrocytes from Rats Exposed to Low Selenium and T-2 Toxin. Biological trace element research\| PubMed ID: 37326932	2024
Integrative analysis of miRNA in cartilage-derived extracellular vesicles and single-cell RNA-seq profiles in knee osteoarthritis. Archives of biochemistry and biophysics\| PubMed ID: 37844826	2023
Comparative Analysis of Gut Microbiota from Rats Induced by Se Deficiency and T-2 Toxin. Nutrients\| PubMed ID: 38140286	2023
Integration of miRNA in exosomes and single-cell RNA-seq profiles in endemic osteoarthritis, Kashin-Beck disease. BioFactors (Oxford, England)\| PubMed ID: 38156801	2024
Involvement of Yes-Associated Protein 1 Activation in the Matrix Degradation of Human-Induced-Pluripotent-Stem-Cell-Derived Chondrocytes Induced by T-2 Toxin and Deoxynivalenol Alone and in ... International journal of molecular sciences\| PubMed ID: 38255951	2024
Identification and Verification of Hub Mitochondrial Dysfunction Genes in Osteoarthritis Based on Bioinformatics Analysis. Journal of immunology research\| PubMed ID: 38292759	2024
Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration. Annals of the rheumatic diseases\| PubMed ID: 38325908	2024
Modulatory interactions of T-2 and deoxynivalenol mycotoxins on murine femoral development and osteological integrity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 38604577	2024
Activation of Notch Signaling Pathway is involved in Extracellular Matrix Degradation in human induced pluripotent stem cells chondrocytes induced by HT-2 toxin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 38734200	2024
HT-2 mycotoxin and selenium deficiency: Effects on Femur development and integrity in Young mice. Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 38768830	2024
Modulation of Ras signaling pathway by exosome miRNAs in T-2 toxin-induced chondrocyte injury. Toxicology\| PubMed ID: 38825033	2024
Combating coal-burning-borne endemic arsenism in Shaanxi Province, Northwest China: The impact of high-arsenic coal ban, improved cook-stoves, and health education. Journal of hazardous materials\| PubMed ID: 39126853	2024
The Impact of Selenium Deficiency and T-2 Toxin on Zip6 Expression in Kashin-Beck Disease. Biological trace element research\| PubMed ID: 39455492	2025
Sex differences in joint pain, limb function and quality of life among patients with Kashin-Beck disease in Northwest China. BMC musculoskeletal disorders\| PubMed ID: 41257713	2025