Jiang Chen

Department of Laboratory Medicine, Zhejiang University School of Medicine

Affiliated withZhejiang University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway. Oncotarget\| PubMed ID: 26376616	2015
Adenoviral delivery of truncated MMP-8 fused with the hepatocyte growth factor mutant 1K1 ameliorates liver cirrhosis and promotes hepatocyte proliferation. Drug design, development and therapy\| PubMed ID: 26527860	2015
Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer. Drug design, development and therapy\| PubMed ID: 26719669	2016
Increasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals. Cell death & disease\| PubMed ID: 29022906	2017
Phosphorylated ERK is a potential prognostic biomarker for Sorafenib response in hepatocellular carcinoma. Cancer medicine\| PubMed ID: 29030911	2017
Ratiometric Mass Spectrometry for Cell Identification and Quantitation Using Intracellular "Dual-Biomarkers". Scientific reports\| PubMed ID: 29234137	2017
Laparoscopy-Assisted versus Open Hepatectomy for Live Liver Donor: Systematic Review and Meta-Analysis. Canadian journal of gastroenterology & hepatology\| PubMed ID: 29238704	2017
Role of probiotics in the treatment of minimal hepatic encephalopathy in patients with HBV-induced liver cirrhosis. The Journal of international medical research\| PubMed ID: 29806520	2018
Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition. Oxidative medicine and cellular longevity\| PubMed ID: 29861830	2018
Optogenetic Stimulation of GABAergic Neurons in the Globus Pallidus Produces Hyperkinesia. Frontiers in behavioral neuroscience\| PubMed ID: 30210317	2018
Metagenomic analysis of viral nucleic acid extraction methods in respiratory clinical samples. BMC genomics\| PubMed ID: 30359242	2018
Restriction of hepatitis B virus replication by c-Abl-induced proteasomal degradation of the viral polymerase. Science advances\| PubMed ID: 30775435	2019
Human mesenchymal stem cells promote tumor growth via MAPK pathway and metastasis by epithelial mesenchymal transition and integrin α5 in hepatocellular carcinoma. Cell death & disease\| PubMed ID: 31142737	2019
The role of natural killer cells in hepatocellular carcinoma development and treatment: A narrative review. Translational oncology\| PubMed ID: 31176993	2019
Author Correction: Human mesenchymal stem cells promote tumor growth via MAPK pathway and metastasis by epithelial mesenchymal transition and integrin α5 in hepatocellular carcinoma. Cell death & disease\| PubMed ID: 31221997	2019
Evaluation of the effects of three sulfa sweeteners on the lifespan and intestinal fat deposition in C. elegans. Food research international (Ottawa, Ont.)\| PubMed ID: 31229125	2019
Resequencing 545 ginkgo genomes across the world reveals the evolutionary history of the living fossil. Nature communications\| PubMed ID: 31519986	2019
Preoperative Serum Fibrinogen is Associated With Acute Kidney Injury after Cardiac Valve Replacement Surgery. Scientific reports\| PubMed ID: 32286477	2020
APEC: an accesson-based method for single-cell chromatin accessibility analysis. Genome biology\| PubMed ID: 32398051	2020
LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription. Theranostics\| PubMed ID: 32754282	2020
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm. Nature communications\| PubMed ID: 32764665	2020
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal transduction and targeted therapy\| PubMed ID: 33361760	2020
Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss. Cell discovery\| PubMed ID: 33390590	2021
Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma. Gut\| PubMed ID: 33431577	2022
Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes. Cell reports\| PubMed ID: 34587478	2021
Plasma ADAM-10 levels and functional outcome of acute primary basal ganglia hemorrhage. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 34852263	2022
Bortezomib-Encapsulated Dual Responsive Copolymeric Nanoparticles for Gallbladder Cancer Targeted Therapy. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 35068071	2022
Occurrence and exposure assessment of aflatoxins in Zhejiang province, China. Environmental toxicology and pharmacology\| PubMed ID: 35283284	2022
CRISPR-Cas9-based genome-wide screening identified novel targets for treating sorafenib-resistant hepatocellular carcinoma: a cross-talk between FGF21 and the NRF2 pathway. Science China. Life sciences\| PubMed ID: 35380342	2022
Gasdermin D-mediated pyroptosis suppresses liver regeneration after 70% partial hepatectomy. Hepatology communications\| PubMed ID: 35509206	2022
Genomic Profiling and Response to Immune Checkpoint Inhibition plus Tyrosine Kinase Inhibition in FH-Deficient Renal Cell Carcinoma. European urology\| PubMed ID: 35715365	2023
Editorial: The role of tumor microenvironment in primary liver cancer therapeutic resistance. Frontiers in oncology\| PubMed ID: 35965496	2022
Occurrence and Exposure Assessment of Deoxynivalenol and Its Acetylated Derivatives from Grains and Grain Products in Zhejiang Province, China (2017-2020). Toxins\| PubMed ID: 36136524	2022
Descriptive study of foodborne disease using disease monitoring data in Zhejiang Province, China, 2016-2020. BMC public health\| PubMed ID: 36171585	2022
STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment. Cancer cell international\| PubMed ID: 36224658	2022
Comparative analysis of the lung microbiota in patients with respiratory infections, tuberculosis, and lung cancer: A preliminary study. Frontiers in cellular and infection microbiology\| PubMed ID: 36389135	2022
Editorial: Chemotherapy in esophageal cancer. Frontiers in oncology\| PubMed ID: 36605431	2022
The Chinese Version of the Perceived Stress Questionnaire-13: Psychometric Properties and Measurement Invariance for Medical Students. Psychology research and behavior management\| PubMed ID: 36643733	2023
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution. Science advances\| PubMed ID: 36696508	2023
Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy. bioRxiv : the preprint server for biology\| PubMed ID: 36747853	2023
Depression and Anxiety Mediate the Association between Sleep Quality and Self-Rated Health in Healthcare Students. Behavioral sciences (Basel, Switzerland)\| PubMed ID: 36829311	2023
Technology Roadmap for Flexible Sensors. ACS nano\| PubMed ID: 36892156	2023
APP mediates tau uptake and its overexpression leads to the exacerbated tau pathology. Cellular and molecular life sciences : CMLS\| PubMed ID: 37071198	2023
Amyloid Precursor Protein: A Regulatory Hub in Alzheimer's Disease. Aging and disease\| PubMed ID: 37307834	2024
Nickle-cobalt alloy nanocrystals inhibit activation of inflammasomes. National science review\| PubMed ID: 37554586	2023
Quantitative Risk Assessment of Five Foodborne Viruses in Shellfish Based on Multiplex qPCR. Foods (Basel, Switzerland)\| PubMed ID: 37761170	2023
Validation of the Chinese version of the Rosenberg Self-Esteem Scale: evidence from a three-wave longitudinal study. BMC psychology\| PubMed ID: 37853499	2023
An Occurrence and Exposure Assessment of Paralytic Shellfish Toxins from Shellfish in Zhejiang Province, China. Toxins\| PubMed ID: 37999487	2023
Amyloid precursor protein facilitates SARS-CoV-2 virus entry into cells and enhances amyloid-β-associated pathology in APP/PS1 mouse model of Alzheimer's disease. Translational psychiatry\| PubMed ID: 38104129	2023
Measurement Properties and Optimal Cutoff Point of the WHO-5 Among Chinese Healthcare Students. Psychology research and behavior management\| PubMed ID: 38148776	2023
Increased A1 astrocyte activation-driven hippocampal neural network abnormality mediates delirium-like behavior in aged mice undergoing cardiac surgery. Aging cell\| PubMed ID: 38155547	2024
Sleep quality and subjective well-being in healthcare students: examining the role of anxiety and depression. Frontiers in public health\| PubMed ID: 38213643	2023
Editorial: The role of tumor microenvironment in the development, treatment and prognosis of hepatocellular carcinoma. Frontiers in pharmacology\| PubMed ID: 38239197	2023
Assessing psychometric properties and measurement invariance of the Sleep Quality Questionnaire among healthcare students. BMC psychology\| PubMed ID: 38243256	2024
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy. Cancer immunology research\| PubMed ID: 38260999	2024
Occurrence and Exposure Assessment of Nickel in Zhejiang Province, China. Toxics\| PubMed ID: 38535902	2024
Occurrence and Exposure Assessment of Lipophilic Shellfish Toxins in the Zhejiang Province, China. Marine drugs\| PubMed ID: 38921550	2024
Longitudinal measurement invariance and psychometric properties of the Patient Health Questionnaire-Four in China. BMC psychiatry\| PubMed ID: 39039478	2024
A longitudinal examination of the measurement properties and invariance of the Sleep Condition Indicator in Chinese healthcare students. BMC psychiatry\| PubMed ID: 39039484	2024
Psychometric properties of the ultra-brief self-report Patient Health Questionnaire-4 (PHQ-4) to assess anxiety and depression in Arabic-speaking adults. BMC psychiatry\| PubMed ID: 39080577	2024
Targeting USP11 regulation by a novel lithium-organic coordination compound improves neuropathologies and cognitive functions in Alzheimer transgenic mice. EMBO molecular medicine\| PubMed ID: 39394468	2024
Hippocampal Nogo66-NgR1 signaling activation restricts postsynaptic assembly in aged mice with postoperative neurocognitive disorders. Aging cell\| PubMed ID: 39412367	2025
Comparative analysis of methodologies for detecting extrachromosomal circular DNA. Nature communications\| PubMed ID: 39448595	2024
The pathogenic APP N-terminal Val225Ala mutation alters tau protein liquid-liquid phase separation and exacerbates synaptic damage. Molecular psychiatry\| PubMed ID: 39558004	2025
Expert consensus on peri-implant keratinized mucosa augmentation at second-stage surgery. International journal of oral science\| PubMed ID: 40537484	2025
Impact of virus-mediated bacterial interactions on acute gastroenteritis symptoms: A new scoring system for clinical assessment. Virulence\| PubMed ID: 40624808	2025
Natural products for intervertebral disc degeneration: mechanistic insights and therapeutic potentials. Frontiers in pharmacology\| PubMed ID: 40786036	2025
Early plasma cytokines associated with multi-drug resistant ventilator-associated pneumonia after neurosurgery: A retrospective cohort study. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases\| PubMed ID: 40945878	2025
Method Development and Sensitivity Optimization Paradigm for One-Step RPA-CRISPR/Cas12a Rapid Detection of the Hard-to-Amplify Gene . Environmental science & technology\| PubMed ID: 41642758	2026
Senescence-associated metabolic alterations aggravate calcific aortic valve disease. European heart journal\| PubMed ID: 41841768	2026