red-blood-cell-distribution-width-to-albumin-ratio-migraine

Red Blood Cell Distribution Width-to-Albumin Ratio and Migraine: Associations with Prevalence and All-Cause Mortality in a Population-Based Study

Migraine is a common primary neurovascular disorder&#160;associated with substantial morbidity and systemic inflammatory alterations. The red blood cell ...

Nanjing University

Sogatella furcifera (Horváth) is a migratory rice pest that periodically erupts across Asia, and early immigration is an important cause of its outbreak. The early immigration of S. furcifera into southern China shows evident annual fluctuations. In the spring of 2012, the huge size of the immigrant population and the large number of immigration peaks were at levels rarely seen prior to that year. However, little research has been done on the entire process of round-trip migration to clarify the development of the population, the long-distance migration and the final eruption. In this study, the light-trap data for S. furcifera in southern China and Vietnam in 2011-2016 were collected, and the trajectory modeling showed that the early immigrants to southern China came from the northern and central Vietnam, Laos, and northeastern Thailand. Analysis of the development of the population, the migration process and meteorological factors revealed the reasons for the huge size of the early immigration: 1) the expansion of the source area could be seen as a precondition; 2) the large size of the returned population in the last autumn and the warm temperature of southern Vietnam and Laos in the last winter increased the initial populations; 3) the sustained strong southwest winds were conducive to the northward migration of the population during the major immigration period in early May. Therefore, the large-scale immigration of S. furcifera to southern China in the spring of 2012 resulted from the combined effects of several factors involved in the process of round-trip migration.

Analysis of the Huge Immigration of Sogatella furcifera (Hemiptera: Delphacidae) to Southern China in the Spring of 2012.

Sevoflurane preconditioning (SPC) results in cerebral ischemic tolerance; however, the mechanism remains unclear. Promoting microglia/macrophages polarization from pro-inflammatory state to anti-inflammatory phenotype has been indicated as a potential treatment target against ischemic stroke. In this study, we aimed to assess the effect of SPC on microglia polarization after stroke and which signaling pathway was involved in this transition.

Sevoflurane preconditioning protects experimental ischemic stroke by enhancing anti-inflammatory microglia/macrophages phenotype polarization through GSK-3β/Nrf2 pathway.

The heavy metal zinc (Zn) is known to be transmitted in the food chain; however, the effect of Zn stress on beans and herbivorous insects is largely unclear. This study aimed to investigate the resistance of broad bean plants to Zn stress and the consequent changes in their physiological and biochemical metabolism by simulating heavy metal pollution in soil. Simultaneously, the effects of aphid progeny treated with different Zn concentrations on the expression of carbohydrate and related genes were analyzed. The results showed that Zn had no effect on the germination rate of broad beans, but other effects mainly manifested as follows. (1) Chlorophyll content decreased. (2) The total soluble sugar and Zn content in stems and leaves increased with increasing Zn content. (3) The proline content first increased and then decreased with increasing Zn content. (4) The height of the seedlings indicates that low concentrations promote growth and high concentrations inhibit growth. In addition, only the first-generation fecundity decreased significantly when aphids fed on heavy metal broad beans. Continuous high Zn levels increase the trehalose content of aphid F1 and F2, while F3 decreases. These results can not only provide a theoretical basis for exploring the impact of soil heavy metal pollution on ecosystems but also preliminarily evaluate the possibility of broad beans as a means of pollution remediation.

Regulation of  L. Response and Its Effect on  Reproduction under Zinc Stress.

Glutamine:fructose-6-phosphate aminotransferases (GFATs) and phosphofructokinase (PFKs) are the principal rate-limiting enzymes involved in hexosamine biosynthesis pathway (HBP) and glycolysis pathway, respectively. In this study, the  and  were knocked down through RNA interference (RNAi) in , the notorious brown planthopper (BPH), and the changes in energy metabolism were determined. Knockdown of either  or  substantially reduced gene expression related to trehalose, glucose, and glycogen metabolism pathways. Moreover, trehalose content rose significantly at 72 h after ds injection, and glycogen content increased significantly at 48 h after injection. Glucose content remained unchanged throughout the experiment. Conversely, ds injection did not significantly alter trehalose, but caused an extreme increase in glucose and glycogen content at 72 h after injection. The Knockdown of  or  significantly downregulated the genes in the glycolytic pathway, as well as caused a considerable and significant decrease in pyruvate kinase (PK) activity after 48 h and 72 h of inhibition. After ds injection, most of genes in TCA cycle pathway were upregulated, but after ds injection, they were downregulated. Correspondingly, ATP content substantially increased at 48 h after  knockdown but decreased to an extreme extent by 72 h. In contrast, ATP content decreased significantly after  was knocked down and returned. The results have suggested the knockdown of either  or  resulted in metabolism disorders in BPHs, highlighting the difference in the impact of those two enzyme genes on energy metabolism. Given their influence on BPHs energy metabolism, developing enzyme inhibitors or activators may provide a biological control for BPHs.

Roles of  and  genes in energy metabolism of brown planthopper, .

The aim of our meta-analysis was to systematically assess the enduring effectiveness and safety of high-frequency spinal stimulation (HF-SCS) in the management of chronic pain.

Long-Term Efficacy and Safety of High-Frequency Spinal Stimulation for Chronic Pain: A Meta-Analysis of Randomized Controlled Trials.

Ethylene Oxide (EO), a volatile organic compound, has garnered considerable attention for its potential impact on human health. Yet, the ramifications of EO exposure on the cognitive functionality of the elderly remain unclear. The aim of this study is to determine whether EO exposure in the elderly correlates with cognitive function. In this cross-sectional study, an analysis was conducted on 471 participants from the 2013 to 2014 United States National Health and Nutrition Examination Survey (NHANES). T1, T2, and T3 was used to represent the low, moderate, and high tertiles of log10-transformed HbEO levels, respectively. Weighted linear regression analysis, weighted logistic regression analysis, and restricted cubic spline models were employed to assess the association between HbEO and standardized z-scores of four cognitive tests. Firstly, analysis of variable characteristics across the different log10-transformed HbEO groups revealed that HbEO was higher in males, non-Hispanic whites, and smokers and that Z scores for Delayed Recall Test (DRT), Animal Fluency Test (AFT), and Digit Symbol Substitution Test (DSST) decreased as HbEO increased (p < 0.05). After adjusting for confounding factors, the log10-transformed HbEO levels were found to be negatively correlated with DRT-Z scores (T3 vs. T1 in Model 3: β (95% CI) = - 0.35 (- 0.54, - 0.15), p = 0.002, p for trend = 0.002). In addition, Stratified analyses showed that the four cognitive scores were negatively correlated with HbEO levels in those under 80 years of age. And men had worse AFT scores compared to women. Overall, the four Z-scores roughly trended downward as log10-transformed HbEO rose. Based on the findings of this research, EO exposure may be associated with adverse performance in the DRT among elderly individuals in the United States.

Article	Year
Analysis of the Huge Immigration of Sogatella furcifera (Hemiptera: Delphacidae) to Southern China in the Spring of 2012. Environmental entomology\| PubMed ID: 29165664	2018
Sevoflurane preconditioning protects experimental ischemic stroke by enhancing anti-inflammatory microglia/macrophages phenotype polarization through GSK-3β/Nrf2 pathway. CNS neuroscience & therapeutics\| PubMed ID: 34370899	2021
Regulation of L. Response and Its Effect on Reproduction under Zinc Stress. International journal of molecular sciences\| PubMed ID: 37298608	2023
Roles of and genes in energy metabolism of brown planthopper, . Frontiers in physiology\| PubMed ID: 37415905	2023
Long-Term Efficacy and Safety of High-Frequency Spinal Stimulation for Chronic Pain: A Meta-Analysis of Randomized Controlled Trials. The Clinical journal of pain\| PubMed ID: 38595082	2024
Association between ethylene oxide exposure and cognitive function in older adults from NHANES data. Scientific reports\| PubMed ID: 39875470	2025

Sisi Sun

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