individualized-periprocedural-management-congenital-dysfibrinogenemia

Individualized Periprocedural Management of Congenital Dysfibrinogenemia during Transvaginal Oocyte Retrieval: A Case Report

Congenital dysfibrinogenemia is a qualitative fibrinogen disorder with phenotypes ranging from isolated laboratory abnormalities to bleeding or ...

The Reproductive Hospital of Guangxi Zhuang Autonomous Region

This analysis aimed to compare the efficacy of oral contraceptive pill (OCP) pretreatment for gonadotropin-releasing hormone antagonist (GnRH-ant) protocol, especially for different responder women. The PubMed, EMBASE, and Chinese National Knowledge Infrastructure (CNKI) databases were searched for trials on with and without OCP pretreatment before stimulation with gonadotropins. The standardized mean differences (SMDs) or pooled risk ratios (RRs) with 95% confidence intervals (CIs) were used for statistical analysis. Fifteen studies with 5326  fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles were summarized. The clinical pregnancy rate, moderate or severe ovarian hyper-stimulation syndrome (OHSS) rate, and miscarriage rate was not found to be significantly different between patients with and those without OCP pretreatment, even after sensitivity analyses. In addition, there were still no statistically significant differences for the subgroups analyses of hyper-responders, poor responders, and normal responders. No significant differences were detected in the duration of ovarian stimulation, gonadotropin dose consumed, endometrial thickness on day of oocyte collection, or number of oocytes. This meta-analysis did not find an unequivocally beneficial effect of OCP pretreatment for different responder women with using a GnRH-ant protocol. The clinician should weigh the advantages and disadvantages of OCP pretreatment and guide the treatment scheduling considering the patient's own situation.

Effects of oral contraceptive for different responder women before GnRH antagonists: a systematic review and meta-analysis.

This study was conducted to understand the association between the AKT2 (AKT serine/threonine kinase 2) gene polymorphism (rs2304186) and PCOS.

Association between AKT2 gene polymorphism and polycystic ovary syndrome: a case-control study.

This study was performed to clarify the effects of angiotensin converting enzyme (ACE) I/D polymorphism on the risk of insulin resistance and polycystic ovary syndrome (PCOS).

Angiotensin Converting Enzyme (ACE) Gene I/D Polymorphism Is Significantly Associated with Insulin Resistance and Polycystic Ovary Syndrome: A Meta-Analysis.

To investigate maternal vitamin E (tocopherol) levels during pregnancy and maternal and neonatal health (MNH) outcomes by using meta-analysis and systematic review of literature.

Correlation of vitamin E level during pregnancy with maternal and neonatal health outcomes: a meta-analysis and systematic review.

This study was aimed to systematically evaluate the efficacy of artificial cycle-prepared frozen-thawed embryo transfer (FET) with or without gonadotrophin-releasing hormone agonist (GnRH-a) pretreatment for women with polycystic ovary syndrome (PCOS).

Article	Year
Effects of oral contraceptive for different responder women before GnRH antagonists: a systematic review and meta-analysis. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology\| PubMed ID: 33975507	2021
Association between AKT2 gene polymorphism and polycystic ovary syndrome: a case-control study. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology\| PubMed ID: 34044676	2021
Angiotensin Converting Enzyme (ACE) Gene I/D Polymorphism Is Significantly Associated with Insulin Resistance and Polycystic Ovary Syndrome: A Meta-Analysis. Gynecologic and obstetric investigation\| PubMed ID: 36966534	2023
Correlation of vitamin E level during pregnancy with maternal and neonatal health outcomes: a meta-analysis and systematic review. American journal of translational research\| PubMed ID: 37434831	2023
Pretreatment with or without GnRH-agonist before frozen-thawed embryo transfer in patients with PCOS: a systematic review and meta-analysis. Journal of ovarian research\| PubMed ID: 38907340	2024

Shujia Wang

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