Christopher A. Koczor

Department of Pharmacology & Mitchell Cancer Institute, University of South Alabama

Affiliated withUniversity of South Alabama

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19513678	2009
Mitochondrial DNA damage initiates a cell cycle arrest by a Chk2-associated mechanism in mammalian cells. The Journal of biological chemistry\| PubMed ID: 19840931	2009
Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress. Nucleic acids research\| PubMed ID: 31287140	2019
NAD-mediated regulation of mammalian base excision repair. DNA repair\| PubMed ID: 33087267	2020
Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD/SIRT6 axis. Cell reports\| PubMed ID: 34731617	2021
NAD bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells. NAR cancer\| PubMed ID: 34806016	2021
Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase. Cancers\| PubMed ID: 35892832	2022
Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens. Cancers\| PubMed ID: 35954352	2022
Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 36515828	2023
Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility. DNA repair\| PubMed ID: 36702010	2023
A multi-scale map of protein assemblies in the DNA damage response. Cell systems\| PubMed ID: 37220749	2023
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage. bioRxiv : the preprint server for biology\| PubMed ID: 38234836	2023
Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity. DNA repair\| PubMed ID: 38897003	2024
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage. DNA repair\| PubMed ID: 40403420	2025
Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis. NAR cancer\| PubMed ID: 41480640	2025
Ubiquitylation of DNA polymerase β via atypical K27 chains signals a DNA damage response. Nucleic acids research\| PubMed ID: 41978267	2026