James S.O. McCullagh

Department of Chemistry, University of Oxford

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Carbon isotope analysis of bulk keratin and single amino acids from British and North American hair. Rapid communications in mass spectrometry : RCM\| PubMed ID: 16220499	2005
Analysis of amino acid 13C abundance from human and faunal bone collagen using liquid chromatography/isotope ratio mass spectrometry. Rapid communications in mass spectrometry : RCM\| PubMed ID: 16921562	2006
Mixed-mode chromatography/isotope ratio mass spectrometry. Rapid communications in mass spectrometry : RCM\| PubMed ID: 20162548	2010
Biophysical characterisation of fibulin-5 proteins associated with disease. Journal of molecular biology\| PubMed ID: 20599547	2010
Analysis of oligonucleotides by hydrophilic interaction liquid chromatography coupled to negative ion electrospray ionization mass spectrometry. Journal of chromatography. A\| PubMed ID: 21741051	2011
Liquid chromatography/isotope ratio mass spectrometry measurement of δ13C of amino acids in plant proteins. Rapid communications in mass spectrometry : RCM\| PubMed ID: 21953952	2011
Single amino acid radiocarbon dating of Upper Paleolithic modern humans. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22517758	2012
Variation of bone collagen amino acid δ13C values in archaeological humans and fauna with different dietary regimes: developing frameworks of dietary discrimination. American journal of physical anthropology\| PubMed ID: 22610935	2012
Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase. The Biochemical journal\| PubMed ID: 23092293	2013
Substrate selectivity analyses of factor inhibiting hypoxia-inducible factor. Angewandte Chemie (International ed. in English)\| PubMed ID: 23296631	2013
Comparing ion-pairing reagents and sample dissolution solvents for ion-pairing reversed-phase liquid chromatography/electrospray ionization mass spectrometry analysis of oligonucleotides. Rapid communications in mass spectrometry : RCM\| PubMed ID: 24395501	2014
Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1. Molecular cell\| PubMed ID: 24486019	2014
A cell-permeable ester derivative of the JmjC histone demethylase inhibitor IOX1. ChemMedChem\| PubMed ID: 24504543	2014
Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases. Nature communications\| PubMed ID: 24594748	2014
Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen. The Biochemical journal\| PubMed ID: 25120187	2014
Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor. The Journal of biological chemistry\| PubMed ID: 26112411	2015
The broad spectrum 2-oxoglutarate oxygenase inhibitor N-oxalylglycine is present in rhubarb and spinach leaves. Phytochemistry\| PubMed ID: 26196940	2015
A method for continuous and stable perfusion of tissue and single cell preparations with accurate concentrations of volatile anaesthetics. Journal of neuroscience methods\| PubMed ID: 26554517	2016
Variability in the carbon isotope composition of individual amino acids in plant proteins from different sources: 1 Leaves. Phytochemistry\| PubMed ID: 26948983	2016
Bioassay-guided isolation of cytotoxic flavonoids from aerial parts of Coronopus didymus. Journal of ethnopharmacology\| PubMed ID: 27989879	2016
Measurement of total phenolic content and antioxidant activity of aerial parts of medicinal plant Coronopus didymus. Asian Pacific journal of tropical medicine\| PubMed ID: 28942828	2017
A Structural Model of a P450-Ferredoxin Complex from Orientation-Selective Double Electron-Electron Resonance Spectroscopy. Journal of the American Chemical Society\| PubMed ID: 29266939	2018
Targeted and Untargeted Metabolic Profiling of Wild Grassland Plants identifies Antibiotic and Anthelmintic Compounds Targeting Pathogen Physiology, Metabolism and Reproduction. Scientific reports\| PubMed ID: 29374230	2018
A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR Spectroscopy. Metabolites\| PubMed ID: 30791611	2019
Metabolomics reveals diet-derived plant polyphenols accumulate in physiological bone. Scientific reports\| PubMed ID: 31142795	2019
Preparative HPLC Separation of Underivatized Amino Acids for Isotopic Analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31347111	2019
Limitations of Deuterium-Labelled Substrates for Quantifying NADPH Metabolism in Heterotrophic Cell Cultures. Metabolites\| PubMed ID: 31569392	2019
Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma. Cancers\| PubMed ID: 31795195	2019
Tibetan , an allele with loss-of-function properties. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32414920	2020
Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells. Communications biology\| PubMed ID: 32433536	2020
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications. Epigenetics\| PubMed ID: 32609604	2021
Interferon-stimulated gene products as regulators of central carbon metabolism. The FEBS journal\| PubMed ID: 33185982	2020
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation. Cell reports\| PubMed ID: 33979616	2021
A lipidomic view of SARS-CoV-2. Bioscience reports\| PubMed ID: 34313294	2021
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal. Nature communications\| PubMed ID: 34321462	2021
Roles of metal ions in the selective inhibition of oncogenic variants of isocitrate dehydrogenase 1. Communications biology\| PubMed ID: 34725432	2021
Isocitrate dehydrogenase gene variants in cancer and their clinical significance. Biochemical Society transactions\| PubMed ID: 34854890	2021
Metabolic adaptations in cancers expressing isocitrate dehydrogenase mutations. Cell reports. Medicine\| PubMed ID: 35028610	2021
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics. EBioMedicine\| PubMed ID: 35152152	2022
Species identification of silks by protein mass spectrometry reveals evidence of wild silk use in antiquity. Scientific reports\| PubMed ID: 35301348	2022
The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation. Physiological reports\| PubMed ID: 35614576	2022
Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation. Cell death & disease\| PubMed ID: 35764612	2022
Polyphenols: Bioavailability, Microbiome Interactions and Cellular Effects on Health in Humans and Animals. Pathogens (Basel, Switzerland)\| PubMed ID: 35890016	2022
Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nature communications\| PubMed ID: 35970853	2022
The influence of pesticides on the corrosion of a Roman bowl excavated in Kent, UK. Scientific reports\| PubMed ID: 36202853	2022
Unlocking the organic residues preserved in the corrosion from the Pewsey Hoard vessels. Scientific reports\| PubMed ID: 36494389	2022
Variants in reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science translational medicine\| PubMed ID: 36542696	2022
Density dependent regulation of inflammatory responses in macrophages. Frontiers in immunology\| PubMed ID: 36591218	2022
Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research. Analytical chemistry\| PubMed ID: 36625129	2023
Trehalose-6-phosphate signaling regulates lateral root formation in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 37748053	2023
-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells. Chemical science\| PubMed ID: 38020377	2023
Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response. Cancer & metabolism\| PubMed ID: 38350962	2024
Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism. Chemical science\| PubMed ID: 38362406	2024
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation. Nature cardiovascular research\| PubMed ID: 38500966	2023
Isolation, separation, identification, and quantification of bioactive methylated flavone regioisomers by UHPLC-MS/MS. Analytical science advances\| PubMed ID: 38715961	2021
Dietary fibre supplementation enhances radiotherapy tumour control and alleviates intestinal radiation toxicity. Microbiome\| PubMed ID: 38745230	2024
New analytical methods focusing on polar metabolite analysis in mass spectrometry and NMR-based metabolomics. Current opinion in chemical biology\| PubMed ID: 38772215	2024
Editorial overview: Recent advances in metabolomics. Current opinion in chemical biology\| PubMed ID: 38981158	2024
Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening. NPJ vaccines\| PubMed ID: 39198486	2024
Correction to: Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response. Cancer & metabolism\| PubMed ID: 39875986	2025
Integrating NMR and multi-LC-MS-based untargeted metabolomics for comprehensive analysis of blood serum samples. Analytica chimica acta\| PubMed ID: 40288864	2025
Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 40684250	2025
A Symbol of Immortality: Evidence of Honey in Bronze Jars Found in a Paestum Shrine Dating to 530-510 BCE. Journal of the American Chemical Society\| PubMed ID: 40736130	2025
Metabolomics using anion-exchange chromatography mass spectrometry for the analysis of cells, tissues and biofluids. Nature protocols\| PubMed ID: 40847241	2026
Formic Acid Pretreatment Enhances Untargeted Serum and Plasma Metabolomics. Analytical chemistry\| PubMed ID: 41056292	2025
Plasma -Glycan Profiling Enhances Diagnostic Precision in Multiple Sclerosis, AQP4-Ab NMOSD, and MOGAD. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 41100797	2025
Changes in the Metabolome of Different Tissues in Response to Streptozotocin Diabetes and Mildronate Exposure: A Metabolomic Assessment. Metabolites\| PubMed ID: 41590669	2026